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Fournisseur:  DWK Life Sciences
Description:   DURAN®, borosilicate glass 3.3, clear.
Fournisseur:  DWK Life Sciences
Description:   DURAN®, borosilicate glass 3.3, clear.
Fournisseur:  WTW ONLINE
Description:   Méthode optique par fluorescence pour une précision et une résolution de mesure supérieures à celles des méthodes électrochimiques. La membrane intelligente dotée de la technologie IQMC permet de calibrer chaque membrane et d'y fixer de façon permanente les données stockées sur une puce.
Fournisseur:  UPCHURCH SCIENTIFIC
Description:   Ces vannes d'arrêt permettent d'arrêter rapidement un écoulement. Les corps sont fabriqués à partir de PEEK ou bien d'ETFE et les deux versions comportent un rotor en PCTFE, ce qui les rend résistants aux substances chimiques. Il a été montré que le colorant bleu utilisé dans les valves de certaines configurations n'était pas entraîné dans les solvants de HPLC habituels.

Fournisseur:  ProSci Inc.
Description:   PAX-8 is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical thyroid adenomas. PAX-8 is expressed in the thyroid (and associated carcinomas), non-ciliated mucosal cells of the fallopian tubes, and simple ovarian inclusion cysts, but not normal ovarian surface epithelial cells. PAX-8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX-8 expression is reported in renal tubules as well as renal cell carcinoma, nephroblastoma, and seminoma. PAX-8 antibody may be used as an additional immunohistochemical marker for renal epithelial tumors.
UOM:  1 * 1 EA
New Product
Fournisseur:  Heidolph Instruments GmbH & Co.KG
Description:   Transforme un agitateur magnétique en une station de travail pour des expériences multiples, améliorez la productivité de votre laboratoire; utilisez un simple agitateur à plaque chauffante pour réaliser des expériences multiples. Pour les expériences simples de chauffage/agitation ou les applications plus complexes telles que la synthèse, les concentrations, les extractions et les distillations. Prend en charge une large gamme d'instruments de laboratoire en verre standard tels que les flacons, les tubes à essai, les béchers et les flacons à fond rond. Une gamme d'inserts est disponible pour les petits flacons ou les flacons à fond rond de 250 ml.
Numéro de catalogue: (PRSI33-748)

Fournisseur:  ProSci Inc.
Description:   Recognises a protein of ~140 kDa, identified as N-Cadherin (NCAD), also known as CDH2 and CD325. CDH2 is a member of the Cadherin superfamily, and consists of five extracellular repeats, a transmembrane domain and a cytoplasmic domain. CDH2 deficient mice die at day 10 of gestation and embryos display major heart defects and malformed neural tubes and somites. Consistent with this, the protein has been implicated in several aspects of cardiac development including the precardiac mesoderm, establishment of left-right symmetry and cardiac looping morphogenesis. Furthermore, it is normally involved in inducing cell cycle arrest and its expression is frequently deregulated in cancer cells. Studies have linked N-cadherin to cancer metastasis by showing the aggressive tumor cells had preferentially turned on N-cadherin as opposed to E- or P-cadherin.
UOM:  1 * 1 EA
New Product
Fournisseur:  HAMILTON BONADUZ
Description:   Ces électrodes sont adaptées aux équipements KNICK® Portamess®. La tête de l'électrode crée un joint hermétique avec le tube de sockage Portamess®.
Numéro de catalogue: (PRSI4297)

Fournisseur:  ProSci Inc.
Description:   PTK7 Antibody: Protein-tyrosine kinases (PTKs) play important roles in regulating cell proliferation and differentiation during development. One member of the PTK family, PTK7, has been suggested to regulate the planar cell polarity (PCP) pathway in vertebrates and may play a role in neural convergent extension and neural tube closure. PTK7 has also been implicated in the development of cancer. Loss of PTK7 expression was seen in several melanoma cell lines and biopsies. Conversely, high-throughput analysis of acute myeloid leukemia samples showed an increased level of PTK7 expression compared to normal bone marrow and purified CD34+ cells. Multiple isoforms of PTK7 are known to exist.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI4299)

Fournisseur:  ProSci Inc.
Description:   PTK7 Antibody: Protein-tyrosine kinases (PTKs) play important roles in regulating cell proliferation and differentiation during development. One member of the PTK family, PTK7, has been suggested to regulate the planar cell polarity (PCP) pathway in vertebrates and may play a role in neural convergent extension and neural tube closure. PTK7 has also been implicated in the development of cancer. Loss of PTK7 expression was seen in several melanoma cell lines and biopsies. Conversely, high-throughput analysis of acute myeloid leukemia samples showed an increased level of PTK7 expression compared to normal bone marrow and purified CD34+ cells. Multiple isoforms of PTK7 are known to exist.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI92-644)

Fournisseur:  ProSci Inc.
Description:   Mesothelin is a cell surface glycoprotein whose expression is limited to mesothelial cells of the serosa (pleura, pericardium, and peritoneum) and epithelial cells of the trachea, tonsils, fallopian tube, and kidneys. Mesothelin plays an important role in cell survival, proliferation, migration, invasion, tumor progression, and resistance to chemotherapy. The overexpression of mesothelin can activate NF-κB and signal transducer and activator of transcription 3 (Stat3), inhibit apoptotic signaling and TNF- alpha-induced apoptosis, and accelerate the G1–S transition. Mesothelin is also found overexpressed in various cancers, including malignant mesothelioma, pancreatic or ovarian carcinoma, sarcomas and in some gastrointestinal or pulmonary carcinomas. As a result of its limited expression in normal tissues, mesothelin has been reported as an ideal tumor-associated marker for the development of targeted therapy.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI29-969)

Fournisseur:  ProSci Inc.
Description:   SHH is a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE). It is also thought that mutations in its gene or in its signalling pathway may be responsible for VACTERL syndrome, which is characterized by vertebral defects, anal atresia, tracheoesophageal fistula with esophageal atresia, radial and renal dysplasia, cardiac anomalies, and limb abnormalities.This gene, which is expressed only during embryogenesis, encodes a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Of three human proteins showing sequence and functional similarity to the sonic hedgehog protein of Drosophila, this protein is the most similar. The protein is made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the developing embryo. Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE), a disorder in which the developing forebrain fails to correctly separate into right and left hemispheres. HPE is manifested by facial deformities. In addition, it is thought that mutations in this gene or in its signalling pathway may be responsible for VACTERL syndrome, which is characterized by vertebral defects, anal atresia, tracheoesophageal fistula with esophageal atresia, radial and renal dysplasia, cardiac anomalies, and limb abnormalities.
UOM:  1 * 50 µG
Fournisseur:  LABCONCO
Description:   All RapidVap® Vertex™ Dry Block evaporators require a Block (not included). Blocks of solid aluminum include stainless steel handles to lift the block in and out of the evaporator. A 0,21" (0,5 cm) diameter port in the upper left hand corner of the block is provided for insertion of the temperature probe to monitor upper block temperature.
Numéro de catalogue: (HYPE9055-022)

Fournisseur:  Thermo Fisher Scientific
Description:   Sample loop, for 9010, 9725 and 9725i injectors, PEEK, 20 µl, Pour tuyau Ø int.: 0,25 mm
UOM:  1 * 1 ST
Fournisseur:  Lenz Laborglas GmbH & CO.KG
Description:   Connectors, made of PBT, red with integrated silicone (VMQ)-PTFE sealing.
Fournisseur:  VARIAN
Description:   La colonne CP-Sil PONA CB fournit une analyse précise des paraffines, oléfines, naphtalènes et substances aromatiques dans les mélanges d'hydrocarbures complexes.
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