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Platinum-Cured+Silicone+Precision+Pump+Tubing
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Platinum-Cured+Silicone+Precision+Pump+Tubing
Numéro de catalogue:
(PRSI25-955)
Fournisseur:
ProSci Inc.
Description:
ATP2B3 gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. ATP2B3 is the plasma membrane calcium ATPase isoform 3.The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 3. Alternatively spliced transcript variants encoding different isoforms have been identified.
UOM:
1 * 50 µG
Fournisseur:
GRANT INSTRUMENTS
Description:
Bain-marie avec agitation, Test tube, Portoir pour tubes à essai, Pour tubes Ø: 13 mm, Nb de places: 44
Numéro de catalogue:
(FSCI91117-10)
Fournisseur:
FINE SCIENCE TOOLS
Description:
Pinces, Pinces de précision, Acier inoxydable, Curved, Pointes: Fine, 100 mm
UOM:
1 * 1 ST
 Il s'agit d'un élément MarketSource. Des frais supplémentaires peuvent s'appliquer.
Numéro de catalogue:
(FSCI91115-10)
Fournisseur:
FINE SCIENCE TOOLS
Description:
Pinces, Pinces de précision, Acier inoxydable, Straight, Pointes: Fine, 110 mm
UOM:
1 * 1 ST
Il s'agit d'un élément MarketSource. Des frais supplémentaires peuvent s'appliquer.
Numéro de catalogue:
(BOSSBS-7048R-FITC)
Fournisseur:
Bioss
Description:
Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalization and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7048R-A350)
Fournisseur:
Bioss
Description:
Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalization and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7048R-CY3)
Fournisseur:
Bioss
Description:
Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalization and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.
UOM:
1 * 100 µl
Numéro de catalogue:
(PRTWPA54BKR)
Fournisseur:
Portwest
Description:
Strong and durable precision engineered aluminium shell torch, uses new CREE technology which is up to 10 times brighter than current L.E.D bulbs.
UOM:
1 * 1 ST
Numéro de catalogue:
(SIMELD5950)
Fournisseur:
Industrial Physics
Description:
Equipment developed to measure the resistivity of paints, varnishes and liquids in a fast and precise way. Indispensable for the correct functioning of electrostatic paint installations.
UOM:
1 * 1 ST
Fournisseur:
Spectrum Laboratories
Description:
Designed for gentle tangential flow filtration of small volumes ranging from 1 to 100 ml. MicroKros® modules are typically operated by a peristaltic pump, these devices also offer the unique advantage of manual operation for quick and convenient separations for small volumes.
Numéro de catalogue:
(FSCI11254-20)
Fournisseur:
FINE SCIENCE TOOLS
Description:
Pinces, Pinces de précision, Auteur: Dumont, Inox, Straight, Pointes: Fine, 110 mm
UOM:
1 * 1 ST
Il s'agit d'un élément MarketSource. Des frais supplémentaires peuvent s'appliquer.
Fournisseur:
HONEYWELL SAFETY
Description:
These Gunn cut gloves made of mixed grain leather provide good mechanical resistance.
Fournisseur:
Thermo Fisher Scientific
Description:
Adaptés à une utilisation avec des microplaques PCR 96 puits, ainsi qu'avec des barrettes de tubes standard et profil bas.
Numéro de catalogue:
(662-0940)
Fournisseur:
VWR Collection
Description:
Les doubles affichages affichent les lux ou les pieds-bougies, ou le pourcentage de différence par rapport à un point de référence, et la source de lumière sélectionnée (lumière du jour, tungstène, fluorescente ou mercure). Le luxmètre Traceable® peut être connecté à un ordinateur ou à un enregistreur de données pour surveiller et conserver les résultats. Pour garantir la précision, un certificat Traceable® avec numéro de série individuel est fourni par un laboratoire d’étalonnage certifié ISO/CEI 17025 et accrédité par A2LA. Cela certifie la traçabilité conformément aux normes du NIST (National Institute of Standards and Technology).
UOM:
1 * 1 ST
Fournisseur:
AESCULAP AG & CO
Description:
These stainless steel rulers are designed for precise measurements.
Numéro de catalogue:
(620-1975)
Fournisseur:
VWR Collection
Description:
Thermomètre digital avec sonde de 500 mm en acier inoxydable, étanche, extra-longue, avec câble (2,5 m)
UOM:
1 * 1 ST
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est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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