Single-use+Pressure+Sensor
Numéro de catalogue:
(613-5041)
Fournisseur:
SOCOREX ISBA
Description:
Filtre de protection, en PE, Pour: VWR SP 100
UOM:
1 * 100 ST
Numéro de catalogue:
(BOSSBS-3686R-CY3)
Fournisseur:
Bioss
Description:
Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF1B. Hydroxylated HIFs are then targeted for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Under hypoxic conditions, the hydroxylation reaction is attenuated allowing HIFs to escape degradation resulting in their translocation to the nucleus, heterodimerization with HIF1B, and increased expression of hypoxy-inducible genes. EGLN1 is the most important isozyme under normoxia and, through regulating the stability of HIF1, involved in various hypoxia-influenced processes such as angiogenesis in retinal and cardiac functionality. Target proteins are preferencially recognized via a LXXLAP motif.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3686R-CY7)
Fournisseur:
Bioss
Description:
Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF1B. Hydroxylated HIFs are then targeted for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Under hypoxic conditions, the hydroxylation reaction is attenuated allowing HIFs to escape degradation resulting in their translocation to the nucleus, heterodimerization with HIF1B, and increased expression of hypoxy-inducible genes. EGLN1 is the most important isozyme under normoxia and, through regulating the stability of HIF1, involved in various hypoxia-influenced processes such as angiogenesis in retinal and cardiac functionality. Target proteins are preferencially recognized via a LXXLAP motif.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3686R-FITC)
Fournisseur:
Bioss
Description:
Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF1B. Hydroxylated HIFs are then targeted for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Under hypoxic conditions, the hydroxylation reaction is attenuated allowing HIFs to escape degradation resulting in their translocation to the nucleus, heterodimerization with HIF1B, and increased expression of hypoxy-inducible genes. EGLN1 is the most important isozyme under normoxia and, through regulating the stability of HIF1, involved in various hypoxia-influenced processes such as angiogenesis in retinal and cardiac functionality. Target proteins are preferencially recognized via a LXXLAP motif.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9022R-CY7)
Fournisseur:
Bioss
Description:
IQCG is a 443 amino acid protein containing one IQ domain. Widely distributed in nature, the IQ domain forms an amphiphilic seven-turn α-helix capable of binding calmodulin in a Ca2+-independent manner. The level of intracellular calcium is tightly regulated in all eukaryotic cells. A modest increase in this level can result in a myriad of physiological responses, most of which are mediated by calmodulin (CaM), the universal calcium sensor. In acute T-lymphoid/myeloid leukemia, IQCG forms a complex with Nup98, an O-linked glycoprotein and a component of the nuclear pore complex. NUP98-IQCG complex bind co-activators and/or co-repressors, which suggest a role in transcriptional regulation.Nup98-IQCG complex inhibits 32Dcl3 cell apoptosis induced by Arabinofuranosylcytosine (Ara-C) and partially blocks granulocyte differentiation induced by G-CSF. IQCG exists as two isoforms due to alternatively splicing events.
UOM:
1 * 100 µl
Numéro de catalogue:
(PRSI30-829)
Fournisseur:
ProSci Inc.
Description:
C20orf141 is a single-pass membrane protein. The exact function of C20orf141 remains unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(MICRSMC6-30B)
Fournisseur:
MICRONOVA
Description:
Les mops sont constitués d'un système de nettoyage plat recouvert de polyester, qui peut être lavé ou autoclavé. Les mops se fixent à l'aide d'adaptateur en acier sur un manche universel.
UOM:
1 * 100 ST
Fournisseur:
Brand
Description:
Adaptateur de micropipette pour le testeur d'étanchéité (4 canaux)
Numéro de catalogue:
(PRSI91-824)
Fournisseur:
ProSci Inc.
Description:
Semaphorin-4B is a single-pass type I membrane protein. SEMA4B is a member of the semaphorin family. The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domain, one PSI domain and one Sema domain. Human SEMA4B is expressed in neurons. SEMA4B inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. SEMA4B negatively regulates basophil-mediated Th2 and humoral memory responses.
UOM:
1 * 50 µG
Fournisseur:
VWR Collection
Description:
The ILCO 180 Premium offers optimal growth conditions for cell cultures and meets demanding requirements for best possible cell growth and maximum sample safety. This CO₂ incubator comes with a built-in, drift-free infrared CO₂ sensor that can be sterilised. Reliable decontamination is provided by the standard-compliant 180 °C hot air sterilisation routine which completely eliminates contaminants and ensures the inner chamber is completely sterilised. This model has an intuitive menu and user friendly software, also USB port for data download to USB stick and for uploading programs. It can be connected to Ethernet or Wi-Fi networks for remote control from any computer, and users can receive notifications about alarms/events via e-mail.
Fournisseur:
Thermo Scientific
Description:
16 rotors pour tubes de 0,2 ml (simples ou 2×8 barrettes) pour microcentrifugeuse mySPIN™ 6
Fournisseur:
Restek
Description:
Sampling bags are cost-effective air sampling device for high level VOC and permanent gases. It features a PP combo valve with hose connection to fit 4,76 mm ID tubing and syringe port with replaceable septum. A single eyelet provides handling convenience.
Numéro de catalogue:
(129-1078)
Fournisseur:
FHP VILEDA SCS
Description:
Dans les environnements contrôlés, les chambres doivent être maintenues parfaitement propres, saines et fiables. Leur propreté doit être irréprochable, et les surfaces doivent être exemptes de particules, de bactéries et de toute contamination. MicroControl est le mop réutilisable haut de gamme conçu et fabriqué par Vileda Professional. Il garantit des performances de nettoyage continues de l'ordre du micron. MicroControl est l'outil indispensable au nettoyage des sols, murs et plafonds.
UOM:
1 * 1 ST
Numéro de catalogue:
(PRSI92-138)
Fournisseur:
ProSci Inc.
Description:
CST Complex Subunit STN1 (OBFC1) is a 368 amino acid protein that contains one OB DNA-binding domain. It is a member of the STN1 family. OBFC1 is component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.
UOM:
1 * 50 µG
Fournisseur:
CLIMATRONIX BVBA
Description:
La chambre de culture tissulaire série CTX-WK a été spécialement conçue pour la culture tissulaire, les tests de germination, la phase de floraison et autres possibilités de recherche. Tous les programmes nécessaires peuvent être mis en œuvre en utilisant le contrôleur PID, qui est convivial et simple à programmer. Simulation jour/nuit grâce à la minuterie programmable sur 24 heures. Les procédés de refroidissement et de déshumidification sont extrêmement rapides grâce au compresseur haute-performance. L'humidificateur à ultrasons HQ garantit également une humidification optimale sans chauffer la pièce. Un capteur d'humidité capacitif garantit une mesure parfaite. L'élément chauffant intégré à l'évaporateur chauffe la zone de test.
Numéro de catalogue:
(BOSSBS-2927R-A680)
Fournisseur:
Bioss
Description:
OXSR1 is a serine/threonine kinase which regulates downstream kinases in response to environmental stress such as osmotic stresses, notably sorbitol and, to a lesser extent, NaCl. OXSR1 phosphorylated thr84 within the N-terminal regulatory domain of PAK1. Replacement of thr84 with gln reduced activation of PAK1 by an active form of the small G protein CDC42, suggesting that phosphorylation by OXSR1 modulates the G protein sensitivity of PAK. OXSR1 interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT. OXSR1 may have a role in regulating the actin cytoskeleton.
UOM:
1 * 100 µl
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