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Fournisseur:  AAT BIOQUEST INC
Description:   Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength.
UOM:  1 * 5 mg
New Product
Numéro de catalogue: (PRSI91-818)

Fournisseur:  ProSci Inc.
Description:   IL10RB is a single- pass type I membrane protein and contains two fibronectin type-III domains. It is an accessory chain which is essential for the active interleukin 10 receptor complex. Coexpression of IL10RB and IL10RA proteins has been shown to be required for IL10-induced signal transduction. Defects in IL10RB are the cause of inflammatory bowel disease type 25 (IBD25) which is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology.
UOM:  1 * 50 µG
Numéro de catalogue: (ICNA097740005)

Fournisseur:  MP Biomedicals
Description:   Film de scellage pour microplaques, Film thermique (96/384 puits), Feuille individuelle/tapis/strip, Plate sealer
UOM:  1 * 100 ST
Fournisseur:  Thermo Fisher Scientific
Description:   The UpCell™ surface is a temperature-responsive cell culture surface that enables harvesting of cells with high viability and intact surface proteins for culture passaging, single-cell analyses and cell transplantation research. The UpCell™ surface enables harvesting of cell sheets and creation of 3D tissue models held together by normal cell junctions and extracellular matrix deposited by the cells.
Numéro de catalogue: (PRSI79-803)

Fournisseur:  ProSci Inc.
Description:   Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates the cleavage of 5'-ssDNA. Negatively regulates sister chromatid exchange (SCE).
UOM:  1 * 1 EA
Numéro de catalogue: (BOSSBS-5221R-A488)

Fournisseur:  Bioss
Description:   This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified. [provided by RefSeq, May 2009].
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified. [provided by RefSeq, May 2009].
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-8444R-A555)

Fournisseur:  Bioss
Description:   This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified. [provided by RefSeq, May 2009].
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-8444R-A647)

Fournisseur:  Bioss
Description:   This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified. [provided by RefSeq, May 2009].
UOM:  1 * 100 µl
Fournisseur:  Corning
Description:   Ces boîtes sont dédiées au transfert des échantillons entre les laboratoires ou sur le terrain.
Numéro de catalogue: (BSBTPB9018)

Fournisseur:  BosterBio
Description:   Polyclonal antibody for CD54/ICAM1 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Mouse. CD54/ICAM1 information: Molecular Weight: 58844 MW; Subcellular Localization: Membrane; Single-pass type I membrane protein; Tissue Specificity: Expressed at low level on a subpopulation of lymphocytes, macrophages, and endothelial cells, but is strongly induced on these cells, and on fibroblasts and epithelial cells.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI56-822)

Fournisseur:  ProSci Inc.
Description:   Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils. [provided by RefSeq].
UOM:  1 * 400 µl
New Product
Numéro de catalogue: (PRSI7417)

Fournisseur:  ProSci Inc.
Description:   La Crosse Virus Nucleocapsid Antibody: La Crosse virus (LCV) is a single-stranded RNA virus that can cause encephalitis in humans and is transmitted predominantly by mosquitoes. It is often mistaken for herpes simplex encephalitis. During human infections, LCV initially presents as a nonspecific summertime illness with fever, headache, nausea, vomiting and lethargy. Death occurs in less than 1% of clinical cases.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI92-469)

Fournisseur:  ProSci Inc.
Description:   V-set and transmembrane domain-containing protein 1 is a single-pass membrane protein. VSTM1 Contains 1 Ig-like V-type domain, in humans is encoded by the VSTM1 gene. It expressed on myeloid (neutrophils, eosinophils and monocytes) but not on lymphoid cells. It behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17). Inhibitory immune receptor involved in the regulation of phagocytes.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI92-241)

Fournisseur:  ProSci Inc.
Description:   SWSAP1 is a nucleus ATPase protein, interacts with ZSWIM7 and forms a functional complex. The complexs involved in homologous recombination repair and stabilises each other. SWS1AP1 also interacts with RAD51, RAD51B, RAD51C, RAD51D and XRCC3. It involves in homologous recombination repair. ATPase is preferentially stimulated by single-stranded DNA and is involved in homologous recombination repair (HRR). SWSAP1 has a DNA-binding activity which is independent of its ATPase activity.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI91-370)

Fournisseur:  ProSci Inc.
Description:   CD83 antigen is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. CD83 is expressed by activated lymphocytes, Langerhans cells and interdigitating reticulum cells. It contains one Ig-like V-type (immunoglobulin-like) domain. , the soluble CD83 has the opposite effect and has an immune inhibitory capacity. Due to its immune inhibitory function, CD83 may play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation.
UOM:  1 * 50 µG
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