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Single-use+Pressure+Sensor
Fournisseur:
EPPENDORF
Description:
La robuste pipette Reference® 2 succède à la pipette Reference®. Elle dispose d'un nouveau design, d'un poids réduit et d'un bouton unique de fonctionnement.
Numéro de catalogue:
(PRSI33-896)
Fournisseur:
ProSci Inc.
Description:
CD45RO is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. CD45RO contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. It has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. It also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. [RefSeq].
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI92-694)
Fournisseur:
ProSci Inc.
Description:
Tumour necrosis factor receptor superfamily member 9(TNFRSF9), also known as CD137 and 4-1BB, is an inducible T cell surface protein belonging to the tumour necrosis factor receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. CD137 is expressed by mesenchymal cells, including endothelial cells, chondrocytes, and cells of the central nervous system. CD137 is also broadly expressed by cells of the human immune system, is broadly expressed by cells of the human immune system, including activated CD8+ and CD4+ T cells, activated natural killer (NK) cells, follicular dendritic cells (FDCs) and monocytes. CD137 has diverse roles in the immune response, the one key function is to promote the survival of both T cells and dendritic cells by binding the cognate ligand CD137L (4-1BBL).
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI33-399)
Fournisseur:
ProSci Inc.
Description:
Recognises an 85-115 kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM1 also binds to CD43 and to Plasmodium falciparum infected RBCs and may also be related to progression and metastasis of tumors.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-097)
Fournisseur:
ProSci Inc.
Description:
This antibody recognises a single chain, transmembrane, heavily glycosylated protein of 90 to 120 kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi’s sarcoma, but shows low specificity.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI79-410)
Fournisseur:
ProSci Inc.
Description:
Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI91-764)
Fournisseur:
ProSci Inc.
Description:
Activin Receptor Type-1B (ACVR1B) is a single-pass type I membrane protein that belongs to the protein kinase superfamily. ACVR1B contains one GS domain and one protein kinase domain and is expressed in many tissues, most strongly in kidney, pancreas, brain, lung, and liver. ACVR1B acts as a transducer of activin or activin like ligands signals. Activin binds to either ACVR2A or ACVR2B and then forms a complex with ACVR1B, ACVR2A or ACVR2B activating ACVR1B through phosphorylation of its regulatory GS domain. They go on to recruit the R-SMADs, SMAD2 and SMAD3. ACVR1B also transducers signals of nodal, GDF-1, and Vg1. Mutations in ACVR1B are associated with pituitary tumors.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI33-067)
Fournisseur:
ProSci Inc.
Description:
This antibody recognises a single protein of 33-34 kDa, identified as the Prostate specific antigen. This PSA antibody is highly specific and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. Prostate specific antigen is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign hyperplasia.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI91-790)
Fournisseur:
ProSci Inc.
Description:
Interleukin-20 Receptor Subunit alpha (IL20RA) is a single-pass type I membrane protein that is a member of the type II cytokine receptor family. IL20RA is synthetized a 553 amino acid glycoprotein precursor containing a 29 amino acid signal peptide, a 221 amino acid extracellular domain with two fibronectin type-III domains, a 24 amino acid transmembrane region, and a 279 amino acid intracellular domain. IL20RA is widely expressed with highest levels found in skin and testis and high levels in brain. IL20RA forms a heterodimer with IL20RB, and the complex serves as a receptor for IL19, IL20 and IL24. IL20RA also forms a heterodimer with the unique and specific receptor IL10RB and functions as the receptor for IL26.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-904)
Fournisseur:
ProSci Inc.
Description:
TNFRSF10B is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces apoptosis signal. The adapter molecule FADD recruits caspase-8 to the activated receptor and is required for the apoptosis mediated by TNFRSF10B. TNFRSF10B is expressed in a number of cell types, and to particularly high levels in lymphocytes and spleen. This single-pass transmembrane protein contains two cysteine-rich repeat units in its extracellular region, followed by a transmembrane segment and a cytoplasmic tail containing a typical “death domain”. TNFRSF10B expression is regulated by the tumor suppressor p53. It is also indicated that the activation of NF-kappa-B can be promoted by TNFRSF10B.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-537)
Fournisseur:
ProSci Inc.
Description:
Interleukin-20 Receptor Subunit alpha (IL20RA) is a single-pass type I membrane protein that is a member of the type II cytokine receptor family. IL20RA is synthetized a 553 amino acid glycoprotein precursor containing a 29 amino acid signal peptide, a 221 amino acid extracellular domain with two fibronectin type-III domains, a 24 amino acid transmembrane region, and a 279 amino acid intracellular domain. IL20RA is widely expressed with highest levels found in skin and testis and high levels in brain. IL20RA forms a heterodimer with IL20RB, and the complex serves as a receptor for IL19, IL20 and IL24. IL20RA also forms a heterodimer with the unique and specific receptor IL10RB and functions as the receptor for IL26.
UOM:
1 * 50 µG
Fournisseur:
HUBER
Description:
De nombreuses applications dépendent d'une source de refroidissement fiable. Les refroidisseurs à circulation de la gamme Unichiller® offrent une solution idéale pour un refroidissement écologique et économique en laboratoire et en milieu industriel. Vous pouvez choisir parmi plus de 50 modèles refroidis par air ou par eau, avec des puissances de refroidissement allant de 0,3 à 50 kW. Une gestion efficace de l'énergie permet de réduire les coûts d'exploitation et l'utilisation d'eau douce. Les refroidisseurs à circulation Huber sont une solution permettant d'économiser les ressources et d'obtenir un retour sur investissement rapide.
Fournisseur:
HAMILTON BONADUZ
Description:
Sensor cable, K8/DIN (for sensors with K8 connector), length 1 m, Pour: Hamilton pH Electrodes
Fournisseur:
iST Scientific Ltd
Description:
Film perméable aux gaz, transparent et perforé. Idéal pour les cultures bactériennes et les cultures de cellules eucaryotes.
Fournisseur:
Corning
Description:
Pipette pack, Axygen® Axypet™, Volume variable, Kit de démarrage Axypet 1, avec une pipette AP-20, AP-200 & AP-1000 et des portoirs supplémentaires pour embouts de pipette Axygen
Numéro de catalogue:
(662-1536)
Fournisseur:
Thermo Orion
Description:
Automatic Temperature Compensation (ATC) probes for fast, accurate measurements in the lab or field.
UOM:
1 * 1 ST
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est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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