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Single-use+Pressure+Sensor
Numéro de catalogue:
(BOSSBS-6582R-A680)
Fournisseur:
Bioss
Description:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesises mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template. At the start of transcription, a single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol II. A bridging helix emanates from RPB1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol II by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition. During transcription elongation, Pol II moves on the template as the transcript elongates. Elongation is influenced by the phosphorylation status of the C-terminal domain (CTD) of Pol II largest subunit (RPB1), which serves as a platform for assembly of factors that regulate transcription initiation, elongation, termination and mRNA processing. Acts as a RNA-dependent RNA polymerase when associated with small delta antigen of Hepatitis delta virus, acting both as a replicate and transcriptase for the viral RNA circular genome.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6582R-A750)
Fournisseur:
Bioss
Description:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesises mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template. At the start of transcription, a single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol II. A bridging helix emanates from RPB1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol II by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition. During transcription elongation, Pol II moves on the template as the transcript elongates. Elongation is influenced by the phosphorylation status of the C-terminal domain (CTD) of Pol II largest subunit (RPB1), which serves as a platform for assembly of factors that regulate transcription initiation, elongation, termination and mRNA processing. Acts as a RNA-dependent RNA polymerase when associated with small delta antigen of Hepatitis delta virus, acting both as a replicate and transcriptase for the viral RNA circular genome.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6581R-A680)
Fournisseur:
Bioss
Description:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesises mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template. At the start of transcription, a single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol II. A bridging helix emanates from RPB1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol II by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition. During transcription elongation, Pol II moves on the template as the transcript elongates. Elongation is influenced by the phosphorylation status of the C-terminal domain (CTD) of Pol II largest subunit (RPB1), which serves as a platform for assembly of factors that regulate transcription initiation, elongation, termination and mRNA processing. Acts as a RNA-dependent RNA polymerase when associated with small delta antigen of Hepatitis delta virus, acting both as a replicate and transcriptase for the viral RNA circular genome.
UOM:
1 * 100 µl
Fournisseur:
Poulten & Graf
Description:
Sterile single use needles made of non corroding steel.
Numéro de catalogue:
(BOSSBS-0225M-HRP)
Fournisseur:
Bioss
Description:
Keyhole limpet hemocyanin is an extremely large, heterogeneous glycosylated protein consisting of subunits with a molecular weight of 350,000 and 390,000 in aggregates with molecular weights of 4,500,000-13,000,000. Each domain of a KLH subunit contains two copper atoms that together bind a single oxygen molecule (O2). When oxygen is bound to hemocyanin, the molecule takes on a distinctive transparent, opalescent blue color. The KLH protein is potently immunogenic yet safe in humans and is therefore highly prized as a vaccine carrier protein. The large and highly glycosylated KLH protein cannot be reproduced synthetically. It is available only as a purified biological product from the Keyhole Limpet Megathura crenulata.Keyhole limpet hemocyanin (KLH) is used extensively as a carrier protein in the production of for research, biotechnology and therapeutic applications. Haptens are substances with a low molecular weight such as peptides, small proteins and drug molecules that are generally not immunogenic and require the aid of a carrier protein to stimulate a response from the immune system in the form of antibody production.[2] KLH is the most widely employed carrier proteins for this purpose. KLH is an effective carrier protein for several reasons. Its large size and numerous epitopes generate a substantial immune response, and abundance of lysine residues for coupling haptens, allows a high hapten:carrier protein ratio increasing the likelihood of generating hapten-specific . In addition, because KLH is derived from the limpet, a gastropod, it is phylogenetically distant from mammalian proteins, thus reducing false positives in immunologically based research techniques in mammalian model organisms.KLH may also be a challenging molecule to work with because of its propensity to aggregate and precipitate. Aggregates remain immunogenic, but limit the ability to conjugate haptens and are difficult to manipulate in the laboratory.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0225M-A488)
Fournisseur:
Bioss
Description:
Keyhole limpet hemocyanin is an extremely large, heterogeneous glycosylated protein consisting of subunits with a molecular weight of 350,000 and 390,000 in aggregates with molecular weights of 4,500,000-13,000,000. Each domain of a KLH subunit contains two copper atoms that together bind a single oxygen molecule (O2). When oxygen is bound to hemocyanin, the molecule takes on a distinctive transparent, opalescent blue color. The KLH protein is potently immunogenic yet safe in humans and is therefore highly prized as a vaccine carrier protein. The large and highly glycosylated KLH protein cannot be reproduced synthetically. It is available only as a purified biological product from the Keyhole Limpet Megathura crenulata.Keyhole limpet hemocyanin (KLH) is used extensively as a carrier protein in the production of for research, biotechnology and therapeutic applications. Haptens are substances with a low molecular weight such as peptides, small proteins and drug molecules that are generally not immunogenic and require the aid of a carrier protein to stimulate a response from the immune system in the form of antibody production.[2] KLH is the most widely employed carrier proteins for this purpose. KLH is an effective carrier protein for several reasons. Its large size and numerous epitopes generate a substantial immune response, and abundance of lysine residues for coupling haptens, allows a high hapten:carrier protein ratio increasing the likelihood of generating hapten-specific . In addition, because KLH is derived from the limpet, a gastropod, it is phylogenetically distant from mammalian proteins, thus reducing false positives in immunologically based research techniques in mammalian model organisms.KLH may also be a challenging molecule to work with because of its propensity to aggregate and precipitate. Aggregates remain immunogenic, but limit the ability to conjugate haptens and are difficult to manipulate in the laboratory.
UOM:
1 * 100 µl
Fournisseur:
OMEGA BIO-TEK
Description:
Le kit d'isolement E.Z.N.A.® HP Total RNA propose une méthode simple et rapide pour l'isolement de l'ARN à partir d'une petite quantité de cellules eucaryotes cultivées ou de tissus. Ce kit permet le traitement unique ou simultané de plusieurs échantillons en moins de 40 minutes. Normalement, 1×10<sup>7</sup> cellules eucaryotes ou 25 à 30 mg de tissu peuvent être utilisés en une seule expérience. Il est inutile de procéder à des extractions au phénol/chloroforme, à des étapes longues telles que l'ultracentrifugation en gradient de CsCl ou la précipitation à l'isopropanol ou LiCl. L'ARN purifié à l'aide de la méthode E.Z.N.A.® HP Total RNA est prêt à l'emploi pour des applications telles que la RT-PCR, la RT-qPCR, le transfert de Northern, la purification d'ARN poly A+ (ARNm), la protection des nucléases et la traduction <i>in vitro</i>.
Fournisseur:
BUCHI
Description:
Vapor temperature sensor. incl. cap nut, seal GL14, measures the vapor temperature inside the system, for Rotavapor® R-300 (for use with the Interface I-300 / I-300 Pro)
Fournisseur:
MEMMERT
Description:
Ce stérilisateur est conforme à toutes les normes et réglementations appropriées sur les produits médicaux. Il garantit la fiabilité des séquences de programme, indépendamment de la charge et du volume de la cuve. La validation de ce stérilisateur à air chaud est possible à tout moment, notamment grâce à la fonction SetpointWAIT. Cette fonction garantit que le programme ne se poursuit que lorsque la température de consigne a été atteinte. Le maintien précis du délai de stérilisation et, par conséquent, l'élimination totale des micro-organismes les plus résistants sont donc garantis en permanence, quels que soient la charge à stériliser et le volume de la cuve. Cette fonction peut également s'utiliser avec des capteurs de température Pt100 supplémentaires et librement positionnables. Dans ce cas, la stérilisation commence uniquement lorsque la température de consigne a été atteinte à tous les points de mesure, à savoir, dans la charge. Pour l'application spéciale de dépyrogénisation, le stérilisateur à air chaud est parfaitement idéal.
Numéro de catalogue:
(620-2829)
Fournisseur:
tempmate
Description:
Pre-programmed. Outstanding single-use temperature and humidity logger for reliable cold chain monitoring. Integrated USB port and PDF and CSV generating software on-board.
UOM:
1 * 20 ST
Numéro de catalogue:
(DRAE6811535)
Fournisseur:
Dräger
Description:
Accessoires pour systèmes de détection de gaz, Pour: For use with the X-am 5000/5600 instruments, XXS OV-A sensor, for use with the X-am 5000/5600 instruments
UOM:
1 * 1 ST
Fournisseur:
Cole Parmer
Description:
Produces cold distilled water for immediate use.
Numéro de catalogue:
(620-2831)
Fournisseur:
tempmate
Description:
Outstanding single-use temperature and humidity logger for reliable cold chain monitoring. Integrated USB port and PDF and CSV generating software on-board.
UOM:
1 * 20 ST
Fournisseur:
Heidolph Instruments GmbH & Co.KG
Description:
Modèles PD 5001 et PD 5006 pour un usage universel. Les pompes péristaltiques sont idéales pour le transport et le dosage de solutions agressives, abrasives ou corrosives, mais également de milieux stériles à faible pression. Le milieu n'entre en contact qu'avec le tuyau, ce qui évite toute contamination. Conviennent au transport de milieux hautement visqueux, jusqu'à 10 000 mPas. Pompes auto-amorçantes, sans joint ni valve. Utilisables dans l'industrie agro-alimentaire pour la filtration et la séparation, dans l'épuration de l'eau, en biotechnologie et pour toutes applications en laboratoire. Possibilité de transport sous pression et sous vide. Moteurs sans entretien pour une longue durée de vie.
Fournisseur:
Corning
Description:
These single-use bags can be connected to tubing via tube welding or by using the pre-assembled multipurpose connectors.
Numéro de catalogue:
(AATB21505)
Fournisseur:
AAT BIOQUEST INC
Description:
Despite the importance of H₂O₂ to human health and disease, the molecular mechanisms of its production, accumulation, trafficking, and function are insufficiently understood due to the lack of sensitive and specific H₂O₂ sensors that can be used in live cells.
UOM:
1 * 1 mg
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