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Single-use+Temperature+Sensor
Numéro de catalogue:
(BOSSBS-9233R-A350)
Fournisseur:
Bioss
Description:
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF180 (ring finger protein 180), also known as Rines, is a 592 single-pass membrane protein that contains a single RING-type zinc finger. Expressed as three alternatively spliced isoforms, RNF180 is well conserved among vertebrates. RNF180 is expressed in brain, kidney, testis and uterus and localizes to the endoplasmic reticulum. RNF180 is an E3 ubiquitin ligase involved in the ubiquitin-proteasome pathway. RNF180 is encoded by a gene located on human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm, or of chromosome 5 altogether, is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-4757R-FITC)
Fournisseur:
Bioss
Description:
Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF. Binds ribosome presumably to drive ribosome nuclear export. Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids. Acts as a chaperonin for the core histones H3, H2B and H4. Stimulates APEX1 endonuclease activity on apurinic/apyrimidinic (AP) double-stranded DNA but inhibits APEX1 endonuclease activity on AP single-stranded RNA. May exert a control of APEX1 endonuclease activity within nucleoli devoted to repair AP on rDNA and the removal of oxidized rRNA molecules. In concert with BRCA2, regulates centrosome duplication. Regulates centriole duplication: phosphorylation by PLK2 is able to trigger centriole replication. Negatively regulates the activation of EIF2AK2/PKR and suppresses apoptosis through inhibition of EIF2AK2/PKR autophosphorylation.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-4757R-A350)
Fournisseur:
Bioss
Description:
Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF. Binds ribosome presumably to drive ribosome nuclear export. Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids. Acts as a chaperonin for the core histones H3, H2B and H4. Stimulates APEX1 endonuclease activity on apurinic/apyrimidinic (AP) double-stranded DNA but inhibits APEX1 endonuclease activity on AP single-stranded RNA. May exert a control of APEX1 endonuclease activity within nucleoli devoted to repair AP on rDNA and the removal of oxidized rRNA molecules. In concert with BRCA2, regulates centrosome duplication. Regulates centriole duplication: phosphorylation by PLK2 is able to trigger centriole replication. Negatively regulates the activation of EIF2AK2/PKR and suppresses apoptosis through inhibition of EIF2AK2/PKR autophosphorylation.
UOM:
1 * 100 µl
Fournisseur:
KINEMATICA
Description:
REACTRON® laboratory systems consist of process vessels (single and multiple wall, standard and customer-specific designs), stirring systems for macro-mixing with anchor stirrer), POLYTRON®/MEGATRON® homogenisers and mixing systems for crushing and micro-mixing, pipework, process controls and accessories, in alignment with the customer, product and process.
Numéro de catalogue:
(90031.)
Fournisseur:
Biotium
Description:
Amine-reactive form of single isomer carboxyrhodamine 110. For certain applications, the dye is preferred over the corresponding 6-carboxyfluorescein because of its exceptional photostability and fluorescence insensitivity to pH change (4-9).
UOM:
1 * 5 mg
Numéro de catalogue:
(BOSSBS-2977R-CY5)
Fournisseur:
Bioss
Description:
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2977R-CY3)
Fournisseur:
Bioss
Description:
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins.
UOM:
1 * 100 µl
Fournisseur:
Avantor Fluid Handling
Description:
Designed with maintenance-free high-accuracy motor and a graphical interface—makes setup and operation easier than ever!
Numéro de catalogue:
(90095.)
Fournisseur:
Biotium
Description:
5-SFX (full name: 6-(Fluorescein-5-carboxamido)hexanoic acid, succinimidyl ester, single isomer) has a 6-atom aminohexanoyl spacer group that separates the fluorescein dye and the amine-reactive group.
UOM:
1 * 5 mg
Numéro de catalogue:
(BERTD05717.20EA)
Fournisseur:
Bertin Instruments
Description:
<B>Optimiser la dissociation des tissus:</B> Le Kit de Dissociation Multi-Tissus Precellys développé par Bertin Technologies est une solution innovante et brevetée conçue pour l'obtention de cellules uniques viables à partir d'échantillons biologiques à des fins de recherche. Il permet l'obtention de cellules uniques de haute qualité à partir de tissus complexes tels que la rate, le foie, le poumon, le cœur et le thymus de souris et ouvre la voie à l'analyse de cellules uniques en aval, telle que la cytométrie de flux ou la NGS.
UOM:
1 * 1 KIT
New Product
Fournisseur:
VWR Collection
Description:
Sonde à oxygène dissous, VWR®, Câble de 4 m
Numéro de catalogue:
(BOSSBS-7719R-CY7)
Fournisseur:
Bioss
Description:
DNA helicase involved in cellular proliferation. Possesses DNA-dependent ATPase and helicase activities. This helicase translocates on single-stranded DNA in the 5' to 3' direction in the presence of ATP and, to a lesser extent, dATP. Its unwinding activity requires a 5'-single-stranded region for helicase loading, since flush-ended duplex structures do not support unwinding. The helicase activity is capable of displacing duplex regions up to 100 bp, which can be extended to 500 bp by RPA or the cohesion establishment factor, the Ctf18-RFC (replication factor C) complex activities. Stimulates the flap endonuclease activity of FEN1. Required for normal sister chromatid cohesion. Required for recruitement of bovine papillomavirus type 1 regulatory protein E2 to mitotic chrmosomes and for viral genome maintenance. Required for maintaining the chromosome segregation and is essential for embryonic development and the prevention of aneuploidy. May function during either S, G2, or M phase of the cell cycle. Binds to both single- and double-stranded DNA.Tissue specificity: Highly expressed in spleen, B-cells, thymus, testis, ovary, small intestine, and pancreas. Very low expression seen in the brain. Expressed in dividing cells and/or cells undergoing high levels of recombination. No expression is seen in cells signaled to terminally differentiate. Expressed in keratinocyte growth factor-stimulated cells but not in serum, EGF and IL1-beta-treated keratinocytes.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7719R-A647)
Fournisseur:
Bioss
Description:
DNA helicase involved in cellular proliferation. Possesses DNA-dependent ATPase and helicase activities. This helicase translocates on single-stranded DNA in the 5' to 3' direction in the presence of ATP and, to a lesser extent, dATP. Its unwinding activity requires a 5'-single-stranded region for helicase loading, since flush-ended duplex structures do not support unwinding. The helicase activity is capable of displacing duplex regions up to 100 bp, which can be extended to 500 bp by RPA or the cohesion establishment factor, the Ctf18-RFC (replication factor C) complex activities. Stimulates the flap endonuclease activity of FEN1. Required for normal sister chromatid cohesion. Required for recruitement of bovine papillomavirus type 1 regulatory protein E2 to mitotic chrmosomes and for viral genome maintenance. Required for maintaining the chromosome segregation and is essential for embryonic development and the prevention of aneuploidy. May function during either S, G2, or M phase of the cell cycle. Binds to both single- and double-stranded DNA.Tissue specificity: Highly expressed in spleen, B-cells, thymus, testis, ovary, small intestine, and pancreas. Very low expression seen in the brain. Expressed in dividing cells and/or cells undergoing high levels of recombination. No expression is seen in cells signaled to terminally differentiate. Expressed in keratinocyte growth factor-stimulated cells but not in serum, EGF and IL1-beta-treated keratinocytes.
UOM:
1 * 100 µl
Fournisseur:
CENTURION SAFETY PRODUCTS
Description:
Ces protections contre les basses températures s'utilisent depuis l'automne et jusqu'au plus froid de l'hiver.
Numéro de catalogue:
(70356-1ML-F)
Fournisseur:
Merck
Description:
Calcium Ionophore IV - Cocktail for membranes, Selectophore™ matériau pour capteur d'ions, Supelco®
UOM:
1 * 1 mL
Numéro de catalogue:
(BOSSBS-1545R-A647)
Fournisseur:
Bioss
Description:
Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodelling and degradation, in cell migration and many other physiopathological events. Plays a direct role in facilitating neuronal migration.
UOM:
1 * 100 µl
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est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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