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Single-use+Temperature+Sensor
Numéro de catalogue:
(PRSI28-828)
Fournisseur:
ProSci Inc.
Description:
TRIM21 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM21 is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus.This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI92-708)
Fournisseur:
ProSci Inc.
Description:
T-Cell Surface Glycoprotein CD3 epsilon Chain (CD3 epsilon ) is a single-pass type I membrane protein. CD3 epsilon contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3 epsilon is a polypeptide encoded by the CD3E gene on chromosome 11 in humans. The T cell receptor-CD3 complex (TCR/CD3 complex) is involved in T-cell development and several intracellular signal-transduction pathways. This complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors. The T cell receptor-CD3 complex is unique in having ten cytoplasmic immunoreceptor tyrosine-based activation motifs (ITAMs). TCR/CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
UOM:
1 * 50 µG
Numéro de catalogue:
(444-0938)
Fournisseur:
GRANT INSTRUMENTS
Description:
Agitateur thermoshake compact avec vitesse et températures variables. Cet agitateur chauffant et refroidissant offre des fonctions de chauffage et de mélange simultanées ou indépendantes. Cette unité est idéale pour l'extraction de l'ADN/ARN, la préparation d'échantillons, les réactions enzymatiques et l'extraction de métabolites de matériaux cellulaires.
UOM:
1 * 1 ST
Numéro de catalogue:
(PRSI92-245)
Fournisseur:
ProSci Inc.
Description:
EGF is a single-pass type I membrane protein,containing 8 LDL-receptor class B repeats and 9 EGF-like domains. EGF results in cellular proliferation, differentiation, and survival.EGF is a low-molecular-weight polypeptide first purified from the mouse submandibular gland, but since then found in many human tissues including submandibular gland, parotid gland. Salivary EGF, which seems also regulated by dietary inorganic iodine, also plays an important physiological role in the maintenance of oro-esophageal and gastric tissue integrity. The biological effects of salivary EGF include healing of oral and gastroesophageal ulcers, inhibition of gastric acid secretion, stimulation of DNA synthesis as well as mucosal protection from intraluminal injurious factors such as gastric acid, bile acids, pepsin, and trypsin and to physical, chemical and bacterial agents.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-960)
Fournisseur:
ProSci Inc.
Description:
Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN- gamma by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PDCD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. PDCD1 has been suggested to be involved in lymphocyte clonal selection and peripheral tolerance, and thus contributes to the prevention of autoimmune diseases. As a cell surface molecule, PDCD1 regulates the adaptive immune response. Engagement of PD-1 by its ligands PD-L1 or PD-L2 transduces a signal that inhibits T-cell proliferation, cytokine production, and cytolytic function.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-510)
Fournisseur:
ProSci Inc.
Description:
B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain. BTLA expression is induced during activation of T cells, and BTLA remains expressed on Th1 cells but not Th2 cells. Like PD1 and CTLA4, BTLA interacts with a B7 homolog, B7H4. However, unlike PD-1 and CTLA-4, BTLA displays T-Cell inhibition via interaction with tumor necrosis family receptors (TNF-R), not just the B7 family of cell surface receptors. BTLA is a lymphocyte inhibitory receptor that inhibits lymphocytes during immune response. BTLA also is a ligand for tumor necrosis factor (receptor) superfamily, member 14 (TNFRSF14), also known as herpes virus entry mediator (HVEM). BTLA-HVEM complexes negatively regulate T-cell immune responses.
UOM:
1 * 50 µG
Fournisseur:
ELTEN
Description:
Sporty ladies safety shoes made from nubuck leather combined with mesh inserts, skin-friendly textile lining, a full padded bellows tongue, collar padding, heel loop, and a dual-density rubber/EVA jo_SPORTY sole (oil, fuel and chemical resistant, temperature resistant from approx. -20 and +200 °C).
Fournisseur:
iST Scientific Ltd
Description:
Pierceable, peelable barrier foil for PCR and sample storage.
Numéro de catalogue:
(KART1540)
Fournisseur:
KARTELL
Description:
PFA, translucent.
UOM:
1 * 1 ST
Fournisseur:
Thermo Fisher Scientific
Description:
Refroidisseurs pour paillasse –20 °C.
PC, bleu. Section inférieure remplie d'un gel non toxique, avec poignée. 471-0000/471-0001 : permet de maintenir une température inférieure à –15 °C pendant une durée pouvant aller jusqu'à 2 heures. Seize inserts inclus pour la conversion d'orifices de 1,5 ml afin d'accepter des tubes de 0,5 ou 0,2 ml.
Numéro de catalogue:
(129-0265)
Fournisseur:
FHP VILEDA SCS
Description:
Pour les applications sèches ou mouillées. Alternative au balai dans des endroits où les poils sont interdits, par ex. pour les sols et les murs en milieu médical. Le MultiSqueegee associe trois composants : un rail en aluminium, une raclette en caoutchouc élastomère (lavable à 70 °C) et un connecteur de manche en PP universel. La raclette en caoutchouc, remplaçable, est dotée d'un bord affiné unique qui entraîne le liquide et la poussière la plus fine en un seul geste.
UOM:
1 * 1 ST
Fournisseur:
SI Analytics
Description:
Pour les petits volumes d'échantillon pour les applications pharmaceutiques et les sciences de la vie.
Fournisseur:
KARTELL
Description:
μAir™ technology ensures high precision, exceeding ISO 8655 standards, by minimizing dead air space between the piston and liquid in the tip. This technology reduces the air compression and allows the user to achieve greater precision during laboratory practices.
Fournisseur:
KARTELL
Description:
μAir™ technology ensures high precision, exceeding ISO 8655 standards, by minimising dead air space between the piston and liquid in the tip. This technology reduces the air compression and allows the user to achieve greater precision during laboratory practices.
Numéro de catalogue:
(PRSI55-073)
Fournisseur:
ProSci Inc.
Description:
Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the d subunit of the Fo complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. In addition, three pseudogenes are located on chromosomes 9, 12 and 15.
UOM:
1 * 400 µl
New Product
Fournisseur:
LEICA MICROSYSTEMS
Description:
Stereo microscopes for electronics and medical device manufacturing industries. The intuitive A60 F and A60 S stereo microscopes fulfil what you need - high sample throughput, optimum visibility of product details and components, and easy processing of subassemblies.
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