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Fournisseur:  Bioss
Description:   Orosomucoid 2 is a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however Orosomucoid 2 appears to function in modulating the activity of the immune system during the acute-phase reaction.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-2969R-A647)

Fournisseur:  Bioss
Description:   E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. Interferes with histone deacetylation mediated by HDAC1 and HDAC2, leading to activation of transcription (By similarity).
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-4184R-CY3)

Fournisseur:  Bioss
Description:   p107 is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   p107 is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-5981R-CY3)

Fournisseur:  Bioss
Description:   p107 is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene.
UOM:  1 * 100 µl
Fournisseur:  Cole-Parmer
Description:   Allows liquids with different boiling points to be heated and or stirred next to each other.

Fournisseur:  Avantor
Description:   This column consists of a highly efficient sulphonated polystyrene resin supplied in the calcium form. It provides excellent separations using only water as the mobile phase.
UOM:  1 * 1 ST
Numéro de catalogue: (BOSSBS-0660R-CY5)

Fournisseur:  Bioss
Description:   Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.
UOM:  1 * 100 µl
Fournisseur:  Cole-Parmer
Description:   Allow liquids with different boiling points to be heated next to each other.
Fournisseur:  VWR Chemicals
Description:   N,N-Diméthylacétamide 99.99-100.00%, PESTINORM® en phase gazeuse Headspace
UOM:  1 * 1 L
Numéro de catalogue: (VERND1069103)

Fournisseur:  Saint Gobain Life Sciences
Description:   Ultra-pure, virgin PTFE boiling stones promote gentle, efficient boiling and help prevent overheating, even of highly volatile liquids. Ideal for continous extraction methods. Stones minimise 'bumping' during reflux and distillation.
UOM:  1 * 450 g

Fournisseur:  Whatman products (Cytiva)
Description:   Recommended for microbiological culturing and sample preparation, these cellulose nitrate membrane filters offer very narrow pore size distribution and low levels of extractables.
UOM:  1 * 100 ST

Fournisseur:  Rockland Immunochemicals
Description:   Anti-Retinoid X Receptor gamma antibody is suitable for use in Western Blotting to detect a single band at approximately 48 kDa corresponding to the RXR-gamma isotype in the appropriate cell lysate or extract.
UOM:  1 * 100 µl
Numéro de catalogue: (ROCK209-406-B92)

Fournisseur:  Rockland Immunochemicals
Description:   This purified antibody has been tested for use in ELISA and western blotting. By western blot a band approximately 15 kDa in size corresponding to human IL-3 Protein is expected in the appropriate cell lysate or extract.
UOM:  1 * 1 EA
Numéro de catalogue: (BOSSBS-6769R-A555)

Fournisseur:  Bioss
Description:   Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome.
UOM:  1 * 100 µl
Numéro de catalogue: (EDVOS-10)

Fournisseur:  EDVOTEK
Description:   Avec cette activité de laboratoire, les étudiants ont la possibilité de voir à quoi ressemble réellement de l'ADN chromosomique et d'explorer les procédures d'extraction de l'ADN.
UOM:  1 * 1 ST
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