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Solid+Phase+Extraction
Numéro de catalogue:
(BOSSBS-9317R-CY5)
Fournisseur:
Bioss
Description:
Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6085R-HRP)
Fournisseur:
Bioss
Description:
Plays a role in the regulation of the circadian clock. Modulates the period length and phase of circadian gene expression and also regulates expression and interaction of the core clock components PER1/2 and CRY1/2. Seems to have an immune potentiation function.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6085R-A350)
Fournisseur:
Bioss
Description:
Plays a role in the regulation of the circadian clock. Modulates the period length and phase of circadian gene expression and also regulates expression and interaction of the core clock components PER1/2 and CRY1/2. Seems to have an immune potentiation function.
UOM:
1 * 100 µl
Fournisseur:
MACRON AVANTOR BRAND
Description:
Eau, ChromAR® pour la chromatographie en phase liquide, pour spectrophotométrie dans l'UV, Macron Fine Chemicals™
Fournisseur:
SORVALL
Description:
These bioprocessing centrifuges offer exceptional performance and large capacities up to 4 or 6 litres to meet the evolving application needs of production facilities. Ideal for bioprocessing and drug discovery.
Numéro de catalogue:
(6043-25)
Fournisseur:
MACRON AVANTOR BRAND
Description:
2,2,4-Triméthylpentane ≥99.5%, ChromAR® pour la chromatographie en phase liquide, pour spectrophotométrie dans l'UV, Macron Fine Chemicals™
UOM:
1 * 2,5 L
Numéro de catalogue:
(BOSSBS-0558R-A350)
Fournisseur:
Bioss
Description:
Epithelial membrane protein-1 (EMP-1) is a four pass transmembrane protein consisting of 160 amino acids. It is a member of a small family of epithelial membrane proteins. EMP-1 is very similar in structure to its close relative, Peripheral Myelin Protein 22 (PMP22). It is most predominantly expressed in tissues of the gastrointestinal tract but has also been found to be a junctional protein in the liver expressed along the intercellular border. EMP-1 directly interacts with the C-terminus of the P2X7 receptor and may be involved in membrane blebbing. EMP-1 may also be an important regulator in cell communication, signaling, and adhesion. When EMP-1 is overexpressed, cell proliferation is inhibited, S phase is arrested and G1 phase is prolonged in esophogeal cancer cells. EMP-1 may play a role in tumorigenesis and has been identified as a biomarker for gefitinib treatment resistance for patients with lung cancer.
UOM:
1 * 100 µl
Numéro de catalogue:
(ENZOADIKAMCC220E)
Fournisseur:
ENZO LIFE SCIENCES
Description:
DNA-topoisomerase II, also known as Topo II or Top 2, is a multifunctional nuclear enzyme required during DNA replication, chromosome disjunction at mitosis, and other DNA-related activities because of its ability to alter DNA supercoiling. In mammalian cells, Topo II consists of two isozymes, Topo II-alpha (170kDa) and Topo II-beta (180kDa) and expression and localization of each isoform are distinct and stage specific during the cell cycle. Topo II-beta is expressed constitutively throughout the cell cycle, whereas the expression of Topo II-alpha is cell cycle-regulated, peaking in G2 to M phase and declining to a minimal level at the end of M phase. DNA-topoisomerase II is the target of some of the most active drugs used in chemotherapy and has been shown to have a critical role in neural development.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(BOSSBS-8445R-CY3)
Fournisseur:
Bioss
Description:
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1360R-CY5.5)
Fournisseur:
Bioss
Description:
In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.
UOM:
1 * 100 µl
Fournisseur:
Whatman products (Cytiva)
Description:
Ces filtres à membrane en cellulose régénérée hydrophile sont des filtres à membrane en cellulose microporeuse produits sans agent mouillant. Le RC60 offre un faible niveau de substances extractibles et une grande compatibilité avec les milieux organiques et aqueux.
Fournisseur:
Thermo Fisher Scientific
Description:
Phosphorylation and dephosphorylation is a molecular on/off switch that regulates a number of key biological pathways within the cell, including signal transduction, cell division, and apoptosis. The Halt Phosphatase Inhibitor Cocktail preserves phosphorylation of proteins in cell lysates and tissue extracts.
Numéro de catalogue:
(BOSSBS-3091R-CY5.5)
Fournisseur:
Bioss
Description:
The cell division control protein cdc2, also known as cyclin dependent kinase 1 (Cdk1) or p34/cdk1, plays a key role in the control of the eukaryotic cell cycle, where it is required for entry into S phase and mitosis. Cdc2 exists as a complex with both cyclin A and cyclin B. The best characterized of these associations is the Cdc2 p34 cyclin B complex, which is required for the G2 to M phase transition. Activation of Cdc2 is controlled at several steps including cyclin binding and phosphorylation of threonine 161. However, the critical regulatory step in activating cdc2 during progression into mitosis appears to be dephosphorylation of Tyr15 and Tyr14. Phosphorylation at Tyr15 and inhibition of Cdc2 is carried out by WEE1 and MIK protein kinases while Tyr15 dephosphorylation and activation of Cdc2 is carried out by the cdc25 phosphatase. The isoform CDC2deltaT is found in breast cancer tissues. Furthermore, cdc2/Cdk1 is a key mediator of neuronal cell death in brain development and degeneration.
UOM:
1 * 100 µl
Numéro de catalogue:
(TB110)
Fournisseur:
G-Biosciences
Description:
Kingdom blot is prepared using total protein extracted from a variety of species, where whole species is not available the whole liver lysate is used. These blots can be used to identify similar proteins in other species, including human, chicken, frog, worm, Drosophila, yeast, Aspergillus, <i>E. coli</i>, Rhizobium and green algae.
UOM:
1 * 1 ST
Numéro de catalogue:
(181-0359)
Fournisseur:
EDWARDS HIGH VACUUM METTLER
Description:
Pump includes all of the components required for laboratory applications such as those found in wet chemistry and sample preparation. It allows for continuous running even in the presence of water and solvents and incorporates an integral fast acting inlet valve that holds the system under vacuum in case of a power failure. Ideal for use with rotary evaporators, centrifugal concentrators, vacuum ovens, distillation/extraction apparatus, fume hoods, glove boxes and vacuum filtration equipment.
UOM:
1 * 1 ST
Fournisseur:
DISCOVER ECHO
Description:
Ce microscope hybride « tout-en-un » peut être utilisé pour les méthodes d’observation droites et inversées.
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