Solid+Phase+Extraction
Numéro de catalogue:
(BOSSBS-4720R-CY3)
Fournisseur:
Bioss
Description:
Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13027R)
Fournisseur:
Bioss
Description:
Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5290R)
Fournisseur:
Bioss
Description:
Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.
UOM:
1 * 100 µl
Numéro de catalogue:
(ENZOALX380222MC25)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Inhibitor of protein kinase C (PKC) and cyclin-dependent kinases (CDKs) resulting in accumulation of cells in the G1 phase and induction of apoptosis. Enhances the cytotoxicity of other anticancer drugs, such as DNA-damaging agents and anti-metabolite drugs, through putative abrogation of G2 and/or S phase accumulation induced by these agents.
UOM:
1 * 0,25 mg
New Product
Numéro de catalogue:
(40064.)
Fournisseur:
Biotium
Description:
Cyanine 555-dUTP can be used to synthesise labeled DNA probes for in-situ hybridization, microarray or blotting techniques.
UOM:
1 * 25 Nmo
Numéro de catalogue:
(ENZOBMLGR2060100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Ah receptor ligand.
UOM:
1 * 1 EA
New Product
Fournisseur:
Sartorius
Description:
This phase separating paper is impregnated with stabilised silicon, thus rendering it hydrophobic and it retains water, but allows solvents to flow through. The flow stops automatically when the entire solvent has passed through, this eliminates the need to use separating funnels.
Numéro de catalogue:
(BOSSBS-5239R-CY5)
Fournisseur:
Bioss
Description:
This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Two alternatively spliced variants, which encode an identical protein, have been reported. Two families of cyclin dependent kinase inhibitors (CKIs) have been identified. The p21WAF1/Cip1 family inhibits all kinases involved in the G1/S transition. The p16INK4a family inhibits Cdk4 and Cdk6 specifically.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5239R-CY3)
Fournisseur:
Bioss
Description:
This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Two alternatively spliced variants, which encode an identical protein, have been reported. Two families of cyclin dependent kinase inhibitors (CKIs) have been identified. The p21WAF1/Cip1 family inhibits all kinases involved in the G1/S transition. The p16INK4a family inhibits Cdk4 and Cdk6 specifically.
UOM:
1 * 100 µl
Fournisseur:
Cayman Chemical
Description:
Gestrinone is a synthetic steroid used occasionally to treat endometriosis.
Numéro de catalogue:
(BOSSBS-5239R-A750)
Fournisseur:
Bioss
Description:
This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Two alternatively spliced variants, which encode an identical protein, have been reported. Two families of cyclin dependent kinase inhibitors (CKIs) have been identified. The p21WAF1/Cip1 family inhibits all kinases involved in the G1/S transition. The p16INK4a family inhibits Cdk4 and Cdk6 specifically.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5239R-FITC)
Fournisseur:
Bioss
Description:
This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Two alternatively spliced variants, which encode an identical protein, have been reported. Two families of cyclin dependent kinase inhibitors (CKIs) have been identified. The p21WAF1/Cip1 family inhibits all kinases involved in the G1/S transition. The p16INK4a family inhibits Cdk4 and Cdk6 specifically.
UOM:
1 * 100 µl
Numéro de catalogue:
(ENZOBMLEA1270025)
Fournisseur:
ENZO LIFE SCIENCES
Description:
GABAB receptor antagonist.
UOM:
1 * 25 mg
New Product
Numéro de catalogue:
(620-2663)
Fournisseur:
VWR Collection
Description:
Le thermomètre laser infrarouge Traceable® est simple à utiliser : allumer, pointer sur l’échantillon et lire le résultat en moins d’une seconde. L’unité offre une lecture en Fahrenheit et en Celsius sur n’importe quelle surface - solide, semi-solide et liquide. Les mesures non invasives, sans contact, le rendent idéal pour la préparation alimentaire, les sciences de la vie, le domaine pharmaceutique, les produits pétroliers, les salles blanches, le domaine électronique et les applications sur site. Le faisceau laser permet une observation parfaite de la cible.
UOM:
1 * 1 ST
Numéro de catalogue:
(ENZOALX550396M005)
Fournisseur:
ENZO LIFE SCIENCES
Description:
TRP channel agonist.
UOM:
1 * 5 mg
New Product
Numéro de catalogue:
(PERSAGBL-7027-0000)
Fournisseur:
PERSONNA MEDICAL
Description:
AccuForge Pop-Up Dispenser provides quick, easy blade access for high volume applications. Each disposable dispenser contains 100 blades constructed of .009" carbon with aluminum back steel and 3-facet edges for sharpness.
UOM:
1 * 100 ST
New Product
Appel de prix
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