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Solid+Phase+Extraction
Fournisseur:
MACHEREY-NAGEL
Description:
Nonpolar GC phase with ultra-low bleeding.
Fournisseur:
CHIRAL TECHNOLOGIES
Description:
When a material is in a state that the temperature and the pressure exceed the critical point, it becomes a supercritical fluid. In this phase, the density of gas and liquid becomes the same.
Numéro de catalogue:
(PRSI91-575)
Fournisseur:
ProSci Inc.
Description:
Mouse Leukemia inhibitory factor（lif）is a secreted protein which belongs to the LIF/OSM family.LIF has been implicated in a many physiological processes including development, hematopoiesis, bone metabolism, and inflammation. it has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.
UOM:
1 * 50 µG
Fournisseur:
Merck
Description:
With their high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level, LiChrosolv® solvents are ideal for reproducible separations. Since separations are normally carried out under gradient conditions in analytical HPLC, we offer solvents in 'gradient grade' as well as 'isocratic grade'. This minimises the gradient effect of the solvent involved.
Fournisseur:
Cayman Chemical
Description:
1-Methoxy-5-methylphenazinium (methyl sulphate) is a photochemically stable mediator of electron transport between NADPH and various electron acceptors such as tetrazolium dyes. It can be used to visualise NAD-linked dehydrogenase activities.
Numéro de catalogue:
(TCIAA5106-1G)
Fournisseur:
TCI
Description:
Vert brillant réactif d'association ionique pour analyse spectrophotométrique
UOM:
1 * 1 g
Fournisseur:
EPPENDORF
Description:
Eppendorf ep Dualfilter T.I.P.S.® SealMax® Racks provide advanced self-sealing pipette tips in 'PCR clean and Sterile' grade, featuring unique two-phase filters for unparalleled protection against contamination in sensitive lab applications.
Numéro de catalogue:
(BOSSBS-3848R-FITC)
Fournisseur:
Bioss
Description:
Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture. Depending on its association with other signal transducers, can regulate different processes. Together with SOS1 and ABI1, forms a trimeric complex that participates in transduction of signals from Ras to Rac by activating the Rac-specific guanine nucleotide exchange factor (GEF) activity. Acts as a direct regulator of actin dynamics by binding actin filaments and has both barbed-end actin filament capping and actin bundling activities depending on the context. Displays barbed-end actin capping activity when associated with ABI1, thereby regulating actin-based motility process: capping activity is auto-inhibited and inhibition is relieved upon ABI1 interaction. Also shows actin bundling activity when associated with BAIAP2, enhancing BAIAP2-dependent membrane extensions and promoting filopodial protrusions. Involved in the regulation of processes such as axonal filopodia growth, stereocilia length, dendritic cell migration and cancer cell migration and invasion. Acts as a regulator of axonal filopodia formation in neurons: in the absence of neurotrophic factors, negatively regulates axonal filopodia formation via actin-capping activity. In contrast, it is phosphorylated in the presence of BDNF leading to inhibition of its actin-capping activity and stimulation of filopodia formation. Component of a complex with DFNB31 and MYO15A that localizes at stereocilia tips and is required for elongation of the stereocilia actin core. Indirectly involved in cell cycle progression; its degradation following ubiquitination being required during G2 phase to promote cell shape changes.
UOM:
1 * 100 µl
Fournisseur:
Thermo Fisher Scientific
Description:
Hypersil™ MOS and MOS-2 columns have a monolayer coverage of C8 alkyl chain chemically bonded onto the silica surface for a reproducible and efficient stationary phase. The MOS-2 is endcapped. Both C8 phases exhibit similar selectivity to ODS, but are less retentive. This can often provide reduced time for analyses, particularly for strongly hydrophobic analytes.
Numéro de catalogue:
(D1065-5MG)
Fournisseur:
SIGMA-ALDRICH MICROSCOPY
Description:
4-(2-[6-(Dioctylamino)-2-naphthalenyl]ethenyl)-1-(3-sulfopropyl)pyridinium inner salt. ≥95% (HPLC), solid (Di-8-ANEPPS)
UOM:
1 * 5 mg
Numéro de catalogue:
(ENZOADI905165100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
HGF/SF (Hepatocyte growth factor/Scatter factor) is a multifunctional heterodimeric polypeptide. It mediates the growth and scattering of various cell types, epithelial mesenchymal transition, the formation of tubules and lumens, and promotes angiogenesis. The ligand-receptor pair has also shown to be uniquely involved in most human solid tumors and to participate in tumor development, invasion, and metastasis.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI79-559)
Fournisseur:
ProSci Inc.
Description:
Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.
UOM:
1 * 1 EA
Numéro de catalogue:
(PIER48895)
Fournisseur:
Thermo Fisher Scientific
Description:
Marfey's Reagent (FDAA or 1-fluoro-2-4-dinitrophenyl-5-L-alanine amide) reacts with primary amines to enable the quick and easy separation and quantitation of optical isomers of amino acids by reverse-phase chromatography.
UOM:
1 * 50 mg
Numéro de catalogue:
(701-0234)
Fournisseur:
VELP SCIENTIFIC
Description:
L'unité de filtration LCR 6 assure la filtration et la phase de lavage finale requise par la méthode enzymatique pour la détermination de fibres alimentaires.
UOM:
1 * 1 ST
Numéro de catalogue:
(BOSSBS-6960R-A680)
Fournisseur:
Bioss
Description:
Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends. The chromatin structure plays an essential role in the V(D)J recombination reactions and the presence of histone H3 trimethylated at 'Lys-4' (H3K4me3) stimulates both the nicking and haipinning steps. The RAG complex also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B lymphocytes. The introduction of DNA breaks by the RAG complex on one immunoglobulin allele induces ATM-dependent repositioning of the other allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. In addition to its endonuclease activity, RAG1 also acts as a E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H3. Histone H3 monoubiquitination is required for the joining step of V(D)J recombination.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6941R-A350)
Fournisseur:
Bioss
Description:
Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends. The chromatin structure plays an essential role in the V(D)J recombination reactions and the presence of histone H3 trimethylated at 'Lys-4' (H3K4me3) stimulates both the nicking and haipinning steps. The RAG complex also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B lymphocytes. The introduction of DNA breaks by the RAG complex on one immunoglobulin allele induces ATM-dependent repositioning of the other allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. In addition to its endonuclease activity, RAG1 also acts as a E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H3. Histone H3 monoubiquitination is required for the joining step of V(D)J recombination.
UOM:
1 * 100 µl
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