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Solid+Phase+Extraction
Numéro de catalogue:
(BOSSBS-3092R-A750)
Fournisseur:
Bioss
Description:
Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1, Bcl-xL/BCL2L1, BRCA2, CALD1, CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CSNK2 proteins/CKII, FZR1/CDH1, CDK7, CEBPB, CHAMP1, DMD/dystrophin, EEF1 proteins/EF-1, EZH2, KIF11/EG5, EGFR, FANCG, FOS, GFAP, GOLGA2/GM130, GRASP1, UBE2A/hHR6A, HIST1H1 proteins/histone H1, HMGA1, HIVEP3/KRC, LMNA, LMNB, LMNC, LBR, LATS1, MAP1B, MAP4, MARCKS, MCM2, MCM4, MKLP1, MYB, NEFH, NFIC, NPC/nuclear pore complex, PITPNM1/NIR2, NPM1, NCL, NUCKS1, NPM1/numatrin, ORC1, PRKAR2A, EEF1E1/p18, EIF3F/p47, p53/TP53, NONO/p54NRB, PAPOLA, PLEC/plectin, RB1, UL40/R2, RAB4A, RAP1GAP, RCC1, RPS6KB1/S6K1, KHDRBS1/SAM68, ESPL1, SKI, BIRC5/survivin, STIP1, TEX14, beta-tubulins, MAPT/TAU, NEDD1, VIM/vimentin, TK1, FOXO1, RUNX1/AML1, SIRT2 and RUNX2. CDK1/CDC2-cyclin-B controls pronuclear union in interphase fertilized eggs. Essential for early stages of embryonic development. During G2 and early mitosis, CDC25A/B/C-mediated dephosphorylation activates CDK1/cyclin complexes which phosphorylate several substrates that trigger at least centrosome separation, Golgi dynamics, nuclear envelope breakdown and chromosome condensation. Once chromosomes are condensed and aligned at the metaphase plate, CDK1 activity is switched off by WEE1- and PKMYT1-mediated phosphorylation to allow sister chromatid separation, chromosome decondensation, reformation of the nuclear envelope and cytokinesis. Inactivated by PKR/EIF2AK2- and WEE1-mediated phosphorylation upon DNA damage to stop cell cycle and genome replication at the G2 checkpoint thus facilitating DNA repair.
UOM:
1 * 100 µl
Numéro de catalogue:
(PRSI26-457)
Fournisseur:
ProSci Inc.
Description:
UGT2A3 is a single-pass type I membrane proteinPotential. It belongs to the UDP-glycosyltransferase family. UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.
UOM:
1 * 50 µG
Fournisseur:
Thermo Scientific
Description:
Vert brillant, pur, haute pureté colorant biologique
Numéro de catalogue:
(PRSI33-313)
Fournisseur:
ProSci Inc.
Description:
This mAb recognises a 21 kDa protein, identified as the p21WAF1 tumor suppressor protein. This mAb is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdk s and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-312)
Fournisseur:
ProSci Inc.
Description:
This mAb recognises a 21 kDa protein, identified as the p21WAF1 tumor suppressor protein. This mAb is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdk s and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).
UOM:
1 * 1 EA
New Product
Fournisseur:
VARIAN
Description:
Select mineral oil provides the shortest analysis time is required with a stabilized, non-polar bonded phase specifically for fast mineral oil analysis.
Fournisseur:
MICROSOLV TECH CORP
Description:
Cogent Amide™ has an amide functional group bonded to the silica-hydride surface direct silicon-carbon bonds. Since the ligand is attached to the surface with direct silicon carbon bonds the bonded phase does not hydrolyze in acidic conditions. Also, it does not make a strong association with acetone.
Numéro de catalogue:
(BOSSBS-0902R-A647)
Fournisseur:
Bioss
Description:
Indole-3-acetic acid, also known as IAA, is a heterocyclic compound that is an phytohormones called auxins. This colourless solid is probably the most important plant auxin. The molecule is derived from indole, containing a carboxymethyl group (acetic acid). IAA has many different effects, as all auxins do, such as inducing cell elongation and cell division with all subsequent results for plant growth and development. There are less expensive and metabolically stable synthetic auxin analogs on the market for use in horticulture, such as indole-3-butyric acid (IBA) and 1-naphthaleneacetic acid (NAA).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0902R-CY5)
Fournisseur:
Bioss
Description:
Indole-3-acetic acid, also known as IAA, is a heterocyclic compound that is an phytohormones called auxins. This colourless solid is probably the most important plant auxin. The molecule is derived from indole, containing a carboxymethyl group (acetic acid). IAA has many different effects, as all auxins do, such as inducing cell elongation and cell division with all subsequent results for plant growth and development. There are less expensive and metabolically stable synthetic auxin analogs on the market for use in horticulture, such as indole-3-butyric acid (IBA) and 1-naphthaleneacetic acid (NAA).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0902R-CY3)
Fournisseur:
Bioss
Description:
Indole-3-acetic acid, also known as IAA, is a heterocyclic compound that is an phytohormones called auxins. This colourless solid is probably the most important plant auxin. The molecule is derived from indole, containing a carboxymethyl group (acetic acid). IAA has many different effects, as all auxins do, such as inducing cell elongation and cell division with all subsequent results for plant growth and development. There are less expensive and metabolically stable synthetic auxin analogs on the market for use in horticulture, such as indole-3-butyric acid (IBA) and 1-naphthaleneacetic acid (NAA).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0902R-A555)
Fournisseur:
Bioss
Description:
Indole-3-acetic acid, also known as IAA, is a heterocyclic compound that is an phytohormones called auxins. This colourless solid is probably the most important plant auxin. The molecule is derived from indole, containing a carboxymethyl group (acetic acid). IAA has many different effects, as all auxins do, such as inducing cell elongation and cell division with all subsequent results for plant growth and development. There are less expensive and metabolically stable synthetic auxin analogs on the market for use in horticulture, such as indole-3-butyric acid (IBA) and 1-naphthaleneacetic acid (NAA).
UOM:
1 * 100 µl
Fournisseur:
Resonac
Description:
Efficacité presque deux fois plus élevée qu'avec les phases inverses polymères traditionnelles.
Fournisseur:
Restek
Description:
Rxi®-5Sil MS stationary phase incorporates phenyl groups in the polymer backbone. This improves thermal stability, reduces bleed, and makes the phase less prone to oxidation. These columns are ideal for GC-MS applications requiring high sensitivity, including use in ion trap systems.
Fournisseur:
Restek
Description:
Ultra IBD is a polar-embedded column that acts as a strong hydrogen bonder and may be the most versatile column available today. It is compatible with 100% aqueous mobile phases and can be used under reversed-phase or HILIC conditions to retain very polar, ionic compounds in highly organic mobile phases.
Numéro de catalogue:
(PRSI79-247)
Fournisseur:
ProSci Inc.
Description:
The protein encoded by Cyclin B1 is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI34-199)
Fournisseur:
ProSci Inc.
Description:
It reacts with Bromodeoxyuridine (BrdU) in single stranded DNA (produced by partial denaturation of double stranded DNA), BrdU coupled to a protein carrier, as well as free BrdU. BrdU is a thymidine analog, incorporated into cell nuclei during DNA synthesis prior to mitosis. Antibody to BrdU is helpful in detecting S-phase cells, providing useful information on the aggressiveness of tumors.
UOM:
1 * 1 EA
New Product
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