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Solid+Phase+Extraction
Fournisseur:
Liebherr
Description:
High-volume freezers with forced air cooling. White steel exterior and stainless-steel interior. The intuitive user interfaces provide useful extended multi-functionality, e.g. a maintenance timer, and the LED interior lighting ensures good visibility of the contents of these large appliances. Advanced connectivity options to suit varying requirements for simplified data storage, temperature control and alarm signals.
Fournisseur:
Restek
Description:
These columns are based on a wide pore material designed for optimal large-molecule separations. Base-deactivated, wide-pore packing exhibits excellent peak shape for a wide range of compounds. Less retention in reversed phase assays than Viva C18 or Viva C8.
Fournisseur:
WTW
Description:
Ces électrodes de pH testées et éprouvées sont faciles à utiliser et offrent une haute qualité et une précision élevée.
Numéro de catalogue:
(80286-1G-F)
Fournisseur:
Merck
Description:
Organic Standard, 2,4,6-Tris(trifluoromethyl)-1,3,5-triazine, Type de conditionnement: Flacon verre pour solides
UOM:
1 * 1 g
Numéro de catalogue:
(PRSI33-311)
Fournisseur:
ProSci Inc.
Description:
This mAb recognises a 21 kDa protein, identified as the p21WAF1 tumor suppressor protein. This mAb is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdk s and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(ENZOADI905163100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
HGF/SF (Hepatocyte growth factor/Scatter factor) is a multifunctional heterodimeric polypeptide. It mediates the growth and scattering of various cell types, epithelial mesenchymal transition, the formation of tubules and lumens, and promotes angiogenesis. The ligand-receptor pair has also shown to be uniquely involved in most human solid tumors and to participate in tumor development, invasion, and metastasis.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(BNUM0433-50)
Fournisseur:
Biotium
Description:
The antibody recognizes the hidden determinant of β-2 microglobulin (i.e. binding to its determinant is available only when the chain is separated from the HLA heavy chain. β-2 microglobulin is a 12 kDa protein with a pI of 5.6. Serum β2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin's lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. β2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy).
UOM:
1 * 50 µl
Numéro de catalogue:
(BOSSBS-0362R-CY7)
Fournisseur:
Bioss
Description:
Protein A is a 40-60 kDa surface protein originally found in the cell wall of the bacteria Staphylococcus aureus (SPA). SPA binds proteins from many of mammalian species, most notably IgGs, and helps inhibit phagocytic engulfment and acts as an immunological disguise via this type of interaction, thus the bacteria will disrupts opsonization and phagocytosis. SPA is known to bind with Fc region of immunoglobulins preferentially through interaction with the VH3 variable region of the heavy chain. SPA has been shown to bind with high affinity to human IgG1 and IgG2 as well as mouse IgG2a and IgG2b, whereas bind with moderate affinity to human IgM, IgA and IgE as well as mouse IgG3 and IgG1. SPA is often produced in E. coli and is practically coupled to other molecules such as enzymes, biotin, radioactive iodine for use in immunology and other biological research. SPA is also immobilized onto solid supports such as agarose beads for total IgG purifying or interest protein or protein complex identifying in immunoprecipitation studies.
UOM:
1 * 100 µl
Fournisseur:
Thermo Fisher Scientific
Description:
These columns are designed for ion pairing reversed phase HPLC (IP-RPLC) analysis of aminoglycoside antibioticss, including drug purity characterisation and quantification, therapeutic drug monitoring and residual control testing in meat / poultry. The Acclaim™ AmG C18 stationary phase is based on a proprietary C18 bonding technology that provides extremely high stability towards acidic conditions.
Numéro de catalogue:
(PRSI79-654)
Fournisseur:
ProSci Inc.
Description:
Cyclin-dependent kinase activity is regulated by T-loop phosphorylation (Thr172 in the case of CDK4), by the abundance of their cyclin partners, and by association with CDK inhibitors of the Cip/Kip or INK family of proteins. The inactive ternary complex of CDK4/cyclin D and p27 Kip1/Cip1 requires extracellular mitogenic stimuli for the release and degradation of p27, which affects progression through the restriction point and pRb-dependent entry into S-phase. The active complex of CDK4/cyclin D targets the retinoblastoma protein for phosphorylation, allowing the release of E2F transcription factors that activate G1/S-phase gene expression. In HeLa cells, upon UV irradiation, upregulation of p16 INK4A association with CDK4/cyclin D3 leads to a G2 delay, implicating CDK4/cyclin D3 activity in progression through the G2-phase of the cell cycle.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI91-925)
Fournisseur:
ProSci Inc.
Description:
Alpha-1-acid glycoprotein 2 is a secreted protein that belongs to the calycin superfamily, lipocalin family.It is expressed by the liver and secreted in plasma. It appears to function in modulating the activity of the immune system during the acute-phase reaction. It functions as transport protein in the blood stream. It binds various hydrophobic ligands in the interior of its beta-barrel domain. It also binds synthetic drugs and influences their distribution and availability.
UOM:
1 * 50 µG
Fournisseur:
PerkinElmer
Description:
Elite-XLB capillary columns are specialty phase for GC/MS with exceptionally low bleed.
Fournisseur:
Avantor
Description:
ULTRAPURE BIOREAGENT—A line of high purity reagents tested for use in biotechnology applications, such as electrophoresis, and liquid chromatography. Where applicable, tests include DNase, RNase, Protease, heavy metals and insoluble matter.
Numéro de catalogue:
(HECH92284504050)
Fournisseur:
GLASWARENFABRIK KARL HECHT
Description:
AR®-Soda-lime glass.
UOM:
1 * 10 kg
Numéro de catalogue:
(PRSI28-611)
Fournisseur:
ProSci Inc.
Description:
Hmg20b is the component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, AOF2/LSD1, RCOR1/CoREST and PHF21A/BHC80. Hmg20b is required for correct progression through G2 phase of the cell cycle and entry into mitosis Hmg20b is also required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.
UOM:
1 * 50 µG
Numéro de catalogue:
(BOSSBS-11619R-A680)
Fournisseur:
Bioss
Description:
Members of the RTP (receptor transporter proteins) family have recently been discovered to influence bitter taste receptor expression in addition to inducing the expression of mammalian odorant receptors. RTP3 is a 232 amino acid single-pass type III membrane protein belonging to the TMEM7 family. Unlike other RTP proteins, RTP3 is not expressed in olfactory neurons but is expressed predominantly in liver. RTP3 is involved in the functional expression of bitter taste receptors and suppresses cell proliferation, and is also found in human circumvallate papillae and testis (regions where bitter taste receptors are expressed). The gene encoding RTP3 maps to human chromosome 3p21.31 within C3CER1 (chromosome 3 common eliminated region 1), which is frequently eliminated in chromosomal deletions of solid tumours.
UOM:
1 * 100 µl
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