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Solid+Phase+Extraction
Fournisseur:
FISCHER LABORTECHNIK GMBH
Description:
DURAN®, verre borosilicaté.
Numéro de catalogue:
(BOSSBS-0362R-CY5)
Fournisseur:
Bioss
Description:
Protein A is a 40-60 kDa surface protein originally found in the cell wall of the bacteria Staphylococcus aureus (SPA). SPA binds proteins from many of mammalian species, most notably IgGs, and helps inhibit phagocytic engulfment and acts as an immunological disguise via this type of interaction, thus the bacteria will disrupts opsonization and phagocytosis. SPA is known to bind with Fc region of immunoglobulins preferentially through interaction with the VH3 variable region of the heavy chain. SPA has been shown to bind with high affinity to human IgG1 and IgG2 as well as mouse IgG2a and IgG2b, whereas bind with moderate affinity to human IgM, IgA and IgE as well as mouse IgG3 and IgG1. SPA is often produced in E. coli and is practically coupled to other molecules such as enzymes, biotin, radioactive iodine for use in immunology and other biological research. SPA is also immobilized onto solid supports such as agarose beads for total IgG purifying or interest protein or protein complex identifying in immunoprecipitation studies.
UOM:
1 * 100 µl
Numéro de catalogue:
(PRSI80-039)
Fournisseur:
ProSci Inc.
Description:
Progesterone receptors (PRs) are nuclear hormone receptors of the NR3C class, which also includes mineralocorticoid,glucocorticoid and androgen receptors. They exist as homodimers coupled to Hsp90 or HMGB proteins, which are shed upon activation. The major signaling pathway used by progesterone receptors is via direct DNA binding and transcriptional regulation of target genes. They can also signal by binding to other proteins, mainly with transcription factors such as NF-kappaB, AP-1 or STAT. Progesterone receptors are found in the female reproductive tract, mammary glands, brain and pituitary gland and receptor expression is induced by estrogen. Well established functions of progesterone receptors include ovulation, implantation, mammary gland development and maintenance of pregnancy. In addition,progesterone, signaling through the progesterone receptor, increases the ventilatory response of the respiratory centers to carbon dioxide and decreases arterial and alveolar PCO2 in the luteal phase of the menstrual cycle and during pregnancy. The human gene encoding the progesterone receptor has been localized to 11q22.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI96-471)
Fournisseur:
ProSci Inc.
Description:
Interleukin 6 receptor (IL6R) is also known as CD126 (Cluster of Differentiation 126) , is a potent pleiotropic cytokine that regulates cell growth and differentiation of various tissues, and is known particularly for its role in the immune response and acute phase reactions. IL6R is a protein complex consisting of a IL-6 receptor subunit (IL6R) and interleukin 6 signal transducer Glycoprotein 130. IL6R also denotes the human gene encoding this subunit. Alternatively spliced transcript variants encoding distinct isoforms have been reported. IL6R subunit also shared by many other cytokines. The soluble form of IL6R arises from proteolytic cleavage of membrane-bound IL6Rα, and acts agonistically by making the IL6 ligand accessible to the signal transducer gp130. Dysregulated production of IL6 and IL6R are implicated in the pathogenesis of several inflammatory diseases and malignancies such as multiple myeloma, rheumatoid arthritis, or osteoporosis, and it has been reported that a humanised anti-IL6R monoclonal antibody is a promising agent applicable to the therapeutic approach for IL6 driven diseases. Interleukin-6 receptor has been shown to interact with Interleukin 6 and Ciliary neurotrophic factor.
UOM:
1 * 50 µG
Fournisseur:
Resonac
Description:
These columns are used to separate by combination of ligand exchange and HILIC modes and can analyse sugars without removing sodium salts in the sample.
Numéro de catalogue:
(PRSI79-526)
Fournisseur:
ProSci Inc.
Description:
Progesterone receptors (PRs) are nuclear hormone receptors of the NR3C class, which also includes mineralocorticoid, glucocorticoid and androgen receptors. They exist as homodimers coupled to Hsp90 or HMGB proteins, which are shed upon activation. The major signaling pathway used by progesterone receptors is via direct DNA binding and transcriptional regulation of target genes. They can also signal by binding to other proteins, mainly with transcription factors such as NF-κB, AP-1 or STAT. Progesterone receptors are found in the female reproductive tract, mammary glands, brain and pituitary gland and receptor expression is induced by estrogen. Well established functions of progesterone receptors include ovulation, implantation, mammary gland development and maintenance of pregnancy. In addition, progesterone, signaling through the progesterone receptor, increases the ventilatory response of the respiratory centers to carbon dioxide and decreases arterial and alveolar PCO2 in the luteal phase of the menstrual cycle and during pregnancy. The human gene encoding the progesterone receptor has been localized to 11q22.
UOM:
1 * 1 EA
Fournisseur:
Sampling Systems
Description:
Les tiges d'éjection des échantillons sont conçues pour faciliter le prélèvement des échantillons.
Numéro de catalogue:
(PRSI25-921)
Fournisseur:
ProSci Inc.
Description:
Organelles of the secretory and endocytic pathways are distinguished by their luminal acidity, which is generated by the activity of an electrogenic vacuolar-type hydrogen ATPase. Progressive acidification of vesicles in the endocytic pathway is essential for the redistribution and degradation of internalized membrane proteins, such as ligand receptor complexes and fluid-phase solutes. It may play an important role in maintaining cation homeostasis and function of the trans-Golgi network.Organelles of the secretory and endocytic pathways are distinguished by their luminal acidity, which is generated by the activity of an electrogenic vacuolar-type hydrogen ATPase. Progressive acidification of vesicles in the endocytic pathway is essential for the redistribution and degradation of internalized membrane proteins, such as ligand receptor complexes and fluid-phase solutes. This gene is expressed predominantly in the trans-Golgi network, and mediates the influx of sodium or potassium in exchange for hydrogen. It may thus play an important role in maintaining cation homeostasis and function of the trans-Golgi network. This gene is part of a gene cluster on chromosome Xp11.23.Organelles of the secretory and endocytic pathways are distinguished by their luminal acidity, which is generated by the activity of an electrogenic vacuolar-type hydrogen ATPase. Progressive acidification of vesicles in the endocytic pathway is essential for the redistribution and degradation of internalized membrane proteins, such as ligand receptor complexes and fluid-phase solutes. This gene is expressed predominantly in the trans-Golgi network, and mediates the influx of sodium or potassium in exchange for hydrogen. It may thus play an important role in maintaining cation homeostasis and function of the trans-Golgi network. This gene is part of a gene cluster on chromosome Xp11.23.
UOM:
1 * 50 µG
Fournisseur:
Thermo Fisher Scientific
Description:
Designed for both liquid and vapor phase storage, the Thermo Scientific™ CryoExtra™ series features automated temperature monitoring and microprocessor-based LN2 level control, providing peace-of-mind for valuable samples.
Numéro de catalogue:
(KAVA271070000)
Fournisseur:
Kavalier
Description:
Borosilicate glass 3.3.
UOM:
1 * 15,6 kg
Fournisseur:
Agilent
Description:
InfinityLab Poroshell 120 HILIC chemistries combine innovative particle technology and bonded phases to improve retention and peak shape for polar analytes. This enables quick and efficient separations of challenging, highly charged polar compounds, and achieves superior analytical sensitivity in MS mode using MS-friendly eluents.
Numéro de catalogue:
(PRSI27-078)
Fournisseur:
ProSci Inc.
Description:
SPDYA regulates the G1/S phase transition of the cell cycle by binding and activating CDC2, CDK2 and CDKN1B/KIP1. SPDYA can activate CDK2 without promoting CDK2 phosphorylation. SPDYA mediates cell survival during the DNA damage process through activation of CDK2.
UOM:
1 * 50 µG
Numéro de catalogue:
(HONC53463-6X1L)
Fournisseur:
Honeywell Chemicals
Description:
Honeywell Chromasolv™ GC-headspace solvents:
UOM:
1 * 6 L
Fournisseur:
Restek
Description:
Ultra amino columns are made of high-purity, spherical shaped type-B silica that minimises activity and creates high-density bonding. These columns are designed for selective and reliable HPLC applications. Aminopropylsilane provides reproducible retention and efficiency for normal-phase or HILIC analysis of simple sugars.
Fournisseur:
VWR Collection
Description:
Ces incubateurs réfrigérés à convection forcée sont dôtés d'une cuve interne en acier inoxydable, la carcasse extérieure est en acier avec finition poudrée. Le modèle IL 68R a une porte extérieure vitrée, les modèles IL 150R/250R une porte extérieure pleine et une porte interne en verre. Toutes les versions comportent un éclairage interne LED, un port d'accès de 30 mm, une horloge et une minuterie, une prise électrique interne, une mémoire interne (qui enregistre jusqu'à 2046 données) et une interface USB (à l'arrière) pour le téléchargement de données vers un PC.
Fournisseur:
Merck
Description:
Grâce au degré élevé de transmissions des UV, au faible taux de particules, au taux faible d'acidité et d'alcalinité et au faible niveau de résidus d'évaporation, les solvants LiChrosolv® sont parfaitement adaptés aux séparations reproductibles. Dans la mesure où les séparations sont normalement effectuées dans des conditions de gradient dans les HPLC analytiques, nous vous proposons des solvants de « qualité gradient », ainsi que des solvants de « qualité isocratique ». Cela vous permet de minimiser l'effet de gradient des solvants utilisés.
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