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Numéro de catalogue:
(BOSSBS-6796R-CY3)
Fournisseur:
Bioss
Description:
Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair. Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1. May act as a CEBPB coactivator in the white adipose tissue to control the expression of a subset of CEBPB downstream target genes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH. When overexpressed in preadipocytes, induces apoptosis or increases cell susceptibility to apoptosis induced by serum deprivation or TGFB treatment. As mature adipocytes, that express high CIDEC levels, are quite resistant to apoptotic stimuli, the physiological significance of its role in apoptosis is unclear. May play a role in the modulation of the response to osmotic stress by preventing NFAT5 to translocate into the nucleus and activate its target genes expression.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7685R-A647)
Fournisseur:
Bioss
Description:
Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide. Isoform 2: has weaker endopeptidase activity compared to isoform 1.
UOM:
1 * 100 µl
Fournisseur:
Bohlender
Description:
Green screw cap, made of PP, for GL 45 threaded bottles and distributor body made of PP.
Numéro de catalogue:
(28-9864-41)
Fournisseur:
Cytiva
Description:
MagRack Maxi is a magnetic rack for small-scale protein purification and sample enrichment with magnetic beads used for sample volumes up to 50 ml.
UOM:
1 * 1 ST
Numéro de catalogue:
(BOSSBS-2189R-HRP)
Fournisseur:
Bioss
Description:
Uromodulin: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure providing the water barrier permeability. May serve as a receptor for binding and endocytosis for cytokines (IL-1, IL-2) and TNF. Facilitates neutrophil migration across renal epithelial (By similarity). Uromodulin, secreted form: Secreted into urine after proteolytically cleaveage. Into the urine, may contribute to colloid osmotic pressure, retards passage of positively charged electrolytes, prevents urinary tract infection and modulates formation of supersaturated salts and their crystals.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1707R-A750)
Fournisseur:
Bioss
Description:
Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. Angiotensin-2: acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesise and secrete aldosterone. Angiotensin-3: stimulates aldosterone release. Angiotensin 1-7: is a ligand for the G-protein coupled receptor MAS1. Has vasodilator and antidiuretic effects. Has an antithrombotic effect that involves MAS1-mediated release of nitric oxide from platelets.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2960R-CY5.5)
Fournisseur:
Bioss
Description:
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8601R-CY3)
Fournisseur:
Bioss
Description:
NHE-3 are integral membrane proteins that are expressed in most mammalian tissues, where they regulate intracellular pH and cell volume. NHEs mediate the transport of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) ions. While NHE-1 is ubiquitously expressed, the NHE isoforms 2-8 have distinct tissue- and cell type-dependent expression and inhibitory characteristics. NHE-3 localizes to the apical membrane of renal proximal tubules where it is responsible for most of the sodium transport and fluid reabsorption. NHE-3 translocates to internal pools where it mediates natriuresis when blood pressure increases abruptly. NHE-3 is also expressed in the stomach and functions to protect the mucosa by secreting protons that diffuse into the mucous cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BELAF188460000)
Fournisseur:
Bel-Art Products, a Part of SP
Description:
Polycarbonate body and clear polycarbonate lid, non-toxic gel-filled.
UOM:
1 * 1 ST
Fournisseur:
ENTEGRIS INC
Description:
Ces filtres sont compatibles avec les gaz haute pureté ainsi que les applications générales relatives à l'azote et CDA. Disponibles avec des niveaux de performances Bronze et Silver, ils sont spécifiquement conçus pour des applications de pression à haut débit et faible pression différentielle. Ils offrent une protection optimale en éliminant tout contaminant susceptible de détériorer la qualité des processus.
Fournisseur:
Thermo Fisher Scientific
Description:
Transport and universal containers have passed the 95 kPa test described in UN packaging instructions 602/650 for transport of infectious substances and diagnostic specimens (except 391-8326). Universal containers are maximum RCF tested (RCF=Relative Centrifugal Force). Caps designed to avoid droplets adhering to the surface giving reduced risk of aerosols.
Numéro de catalogue:
(BOSSBS-12927R-A647)
Fournisseur:
Bioss
Description:
Cytochrome P450 proteins are heme-thiolate monooxygenases that mediate NADPH-dependent electron transport and function to oxidize a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Specifically, Cytochrome P450s are responsible for metabolizing arachidonic acid to hydroxyeicosatetraenoic acid (a regulator of blood pressure) and epoxyeicosatrienoic acid (a molecule involved in signaling events). CYP20A1 (cytochrome P450, family 20, subfamily A, polypeptide 1), also known as CYP-M, is a 462 amino acid single-pass membrane protein that belongs to the cytochrome P450 family. CYP20A1 is thought to carry its own oxygen as it lacks a conserved I-helix motif and one amino acid of its conserved heme binding site.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12927R-FITC)
Fournisseur:
Bioss
Description:
Cytochrome P450 proteins are heme-thiolate monooxygenases that mediate NADPH-dependent electron transport and function to oxidize a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Specifically, Cytochrome P450s are responsible for metabolizing arachidonic acid to hydroxyeicosatetraenoic acid (a regulator of blood pressure) and epoxyeicosatrienoic acid (a molecule involved in signaling events). CYP20A1 (cytochrome P450, family 20, subfamily A, polypeptide 1), also known as CYP-M, is a 462 amino acid single-pass membrane protein that belongs to the cytochrome P450 family. CYP20A1 is thought to carry its own oxygen as it lacks a conserved I-helix motif and one amino acid of its conserved heme binding site.
UOM:
1 * 100 µl
Numéro de catalogue:
(BELAF308880010)
Fournisseur:
Bel-Art Products, a Part of SP
Description:
PVDF, translucent
UOM:
1 * 1 ST
Fournisseur:
EPPENDORF
Description:
Cool samples safely and efficiently using the Eppendorf® IsoTherm-System. Choose between IsoPacks for 0 °C and –21 °C and use the IsoRack for centrifuging, transporting, or storing, ensuring constant temperature maintenance throughout your workflow.
Fournisseur:
Cytiva (Formerly Pall Lab)
Description:
Membranes en nylon 6,6 pour la filtration des fluides pour l'industrie pharmaceutique, biotechnologique, électronique, agroalimentaire, et pour les applications analytiques. Ces membranes sont très résistantes aux contraintes mécaniques, chimiques et thermiques. Elles s'utilisent dans les deux sens, sont intrinsèquement hydrophiles, présentent des débits élevés, de faibles chutes de pression et très peu de substances extractibles. Le cas échéant, elles se stérilisent à la vapeur sans altération du débit ou du seuil de rétention.
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