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ULTRA+RESI-ANALYZED
Fournisseur:
VWR Collection
Description:
Kit de dégivrage, Pour: Congélateur ULT VWR 352
Fournisseur:
VWR Collection
Description:
VWR® ULT Eco Premium Les congélateurs sont conçus pour un stockage sûr et fiable des échantillons sensibles. Ils se caractérisent par une commande ergonomique et une faible consommation d'énergie.
Fournisseur:
VWR Collection
Description:
Ces pH-mètres économiques, robustes et étanches sont fournis dans des kits complets prêts à l'emploi qui intègrent une mallette de transport robuste, une électrode et un capteur de température avec différentes longueurs de câble et tampons.
Numéro de catalogue:
(BOSSBS-10235R-A647)
Fournisseur:
Bioss
Description:
Pokemon, the POK erythroid myeloid ontogenic factor, not only regulates the expression of many genes, but also plays an important role in cell tumorigenesis. To investigate the molecular mechanism regulating expression of the Pokemon gene in humans, its 5'-upstream region was cloned and analyzed. Transient analysis revealed that the Pokemon promoter is constitutive. Deletion analysis and a DNA decoy assay indicated that the NEG-U and NEG-D elements were involved in negative regulation of the Pokemon promoter, whereas the POS-D element was mainly responsible for its strong activity. Electrophoretic mobility shift assays suggested that the NEG-U, NEG-D and POS-D elements were specifically bound by the nuclear extract from A549 cells in vitro. Mutation analysis demonstrated that cooperation of the NEG-U and NEG-D elements led to negative regulation of the Pokemon promoter. Moreover, the NEG-U and NEG-D elements needed to be an appropriate distance apart in the Pokemon promoter in order to cooperate. Taken together, our results elucidate the mechanism underlying the regulation of Pokemon gene transcription, and also define a novel regulatory sequence that may be used to decrease expression of the Pokemon gene in cancer gene therapy.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-10235R-A350)
Fournisseur:
Bioss
Description:
Pokemon, the POK erythroid myeloid ontogenic factor, not only regulates the expression of many genes, but also plays an important role in cell tumorigenesis. To investigate the molecular mechanism regulating expression of the Pokemon gene in humans, its 5'-upstream region was cloned and analyzed. Transient analysis revealed that the Pokemon promoter is constitutive. Deletion analysis and a DNA decoy assay indicated that the NEG-U and NEG-D elements were involved in negative regulation of the Pokemon promoter, whereas the POS-D element was mainly responsible for its strong activity. Electrophoretic mobility shift assays suggested that the NEG-U, NEG-D and POS-D elements were specifically bound by the nuclear extract from A549 cells in vitro. Mutation analysis demonstrated that cooperation of the NEG-U and NEG-D elements led to negative regulation of the Pokemon promoter. Moreover, the NEG-U and NEG-D elements needed to be an appropriate distance apart in the Pokemon promoter in order to cooperate. Taken together, our results elucidate the mechanism underlying the regulation of Pokemon gene transcription, and also define a novel regulatory sequence that may be used to decrease expression of the Pokemon gene in cancer gene therapy.
UOM:
1 * 100 µl
Fournisseur:
WTW
Description:
Integratable adapters for connecting Multi IDS meters with conventional pH/ORP/ISE electrodes.
Numéro de catalogue:
(171-2709)
Fournisseur:
VWR Collection
Description:
Cartouche de déminéralisation FLODEM à usage unique, VWR®
UOM:
1 * 1 ST
Numéro de catalogue:
(BOSSBS-10235R-CY5)
Fournisseur:
Bioss
Description:
Pokemon, the POK erythroid myeloid ontogenic factor, not only regulates the expression of many genes, but also plays an important role in cell tumorigenesis. To investigate the molecular mechanism regulating expression of the Pokemon gene in humans, its 5'-upstream region was cloned and analyzed. Transient analysis revealed that the Pokemon promoter is constitutive. Deletion analysis and a DNA decoy assay indicated that the NEG-U and NEG-D elements were involved in negative regulation of the Pokemon promoter, whereas the POS-D element was mainly responsible for its strong activity. Electrophoretic mobility shift assays suggested that the NEG-U, NEG-D and POS-D elements were specifically bound by the nuclear extract from A549 cells in vitro. Mutation analysis demonstrated that cooperation of the NEG-U and NEG-D elements led to negative regulation of the Pokemon promoter. Moreover, the NEG-U and NEG-D elements needed to be an appropriate distance apart in the Pokemon promoter in order to cooperate. Taken together, our results elucidate the mechanism underlying the regulation of Pokemon gene transcription, and also define a novel regulatory sequence that may be used to decrease expression of the Pokemon gene in cancer gene therapy.
UOM:
1 * 100 µl
Fournisseur:
VWR Collection
Description:
Ce système de purification d’eau performant, muni d’une interface intuitive, est destiné aux laboratoires; à partir d’eau osmosée (technologie RO), d’eau distillée ou déionisée, il génère de l’eau ultra pure de type I. La qualité de l’eau ultra pure ainsi produite remplit, voire dépasse les exigences respectives des normes CLSI et CAP en matière d’eau de type I.
Numéro de catalogue:
(39771.KT)
Fournisseur:
Thermo Scientific
Description:
This pocket size pH meter is supplied with a rugged, epoxy-body pH electrode.
UOM:
1 * 1 ST
Numéro de catalogue:
(BOSSBS-8042R-CY3)
Fournisseur:
Bioss
Description:
The Major facilitator superfamily consists of presumed carbohydrate transporters with 10-12 membrane-spanning domains. Belonging to the facilitator superfamily, HIAT1 is a 490 amino acid multi-pass membrane protein that may function as a sugar transporter and is expressed in adult and embryonic brain. The HIAT1 gene was first observed while analyzing for active genes in neonatal mouse hippocampus. The gene encoding HIAT1 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. Stickler syndrome, Parkinsons, schizophrenia, familial adenomatous polyposis, Gaucher disease and Usher syndrome are also associated with chromosome 1.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8042R-CY5.5)
Fournisseur:
Bioss
Description:
The Major facilitator superfamily consists of presumed carbohydrate transporters with 10-12 membrane-spanning domains. Belonging to the facilitator superfamily, HIAT1 is a 490 amino acid multi-pass membrane protein that may function as a sugar transporter and is expressed in adult and embryonic brain. The HIAT1 gene was first observed while analyzing for active genes in neonatal mouse hippocampus. The gene encoding HIAT1 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. Stickler syndrome, Parkinsons, schizophrenia, familial adenomatous polyposis, Gaucher disease and Usher syndrome are also associated with chromosome 1.
UOM:
1 * 100 µl
Numéro de catalogue:
(665-0480)
Fournisseur:
VWR Collection
Description:
Ce testeur est un instrument de type stylo pratique pour mesurer les paramètres de qualité de l'eau suivants : pH, conductivité, TDS, salinité et température.
UOM:
1 * 1 ST
Numéro de catalogue:
(662-2351)
Fournisseur:
VWR Collection
Description:
Ces pH-mètres économiques, robustes et étanches sont fournis en kits complets, prêts à l'emploi, composés d'une mallette de transport robuste, d'une électrode et d'une sonde de température avec différentes longueurs de câbles et des tampons.
UOM:
1 * 1 ST
Fournisseur:
VWR Collection
Description:
Our VWR® laboratory-grade water purification systems feature an inspiring, application-oriented design. Perform your workflows faster and more reliably, simplifying your daily lab work while ensuring cost-efficient operation over the long term. All instruments offer flexible solutions as they can be adapted to your requirements and integrated into your laboratory environment.
Numéro de catalogue:
(0944-1L)
Fournisseur:
VWR Chemicals
Description:
Alcool isoamylique ≥99%, Qualité ultra pure
UOM:
1 * 1 L
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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'
est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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Les produits marqués de ce symbole ne seront bientôt plus disponibles - vente jusqu'à épuisement de stock. Des alternatives peuvent être disponibles en recherchant le code article VWR indiqué ci-dessus. Si vous avez besoin d'une assistance supplémentaire, veuillez contacter notre Service Clientèle au 016 385 011.
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