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block+heaters+
Numéro de catalogue:
(BOSSBS-8191R-A350)
Fournisseur:
Bioss
Description:
Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1049R-A647)
Fournisseur:
Bioss
Description:
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1049R-A555)
Fournisseur:
Bioss
Description:
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0792R-FITC)
Fournisseur:
Bioss
Description:
Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
UOM:
1 * 100 µl
Numéro de catalogue:
(ENZOBMLEI1180010)
Fournisseur:
ENZO LIFE SCIENCES
Description:
A potent and specific substrate analog PLA2 inhibitor (IC50=6.2 µM-porcine pancreatic PLA2). It inhibits human recombinant sPLA2 (IC50=13.7 µM) selectively over cPLA2. At 1 µM it completely blocked the myogenic response in perfused dog renal arcuate arteries.
UOM:
1 * 10 mg
New Product
Numéro de catalogue:
(BOSSBS-1235R-A680)
Fournisseur:
Bioss
Description:
May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth (By similarity). Overexpression of HYAL1 suppressed the growth rate of colon carcinoma cell tumors in an experimental model.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1235R-A350)
Fournisseur:
Bioss
Description:
May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth (By similarity). Overexpression of HYAL1 suppressed the growth rate of colon carcinoma cell tumors in an experimental model.
UOM:
1 * 100 µl
Numéro de catalogue:
(ENZOBMLEI3600005)
Fournisseur:
ENZO LIFE SCIENCES
Description:
PD-98059 is a potent and selective inhibitor of MAP kinase kinase (MEK). It selectively blocks the activation of MEK thereby inhibiting the phosphorylation and the activation of MAP kinase. PD-98059 is cell permeable. In PC12 pheochromocytoma cells, it completely blocked the increase in MAP kinase activity produced by NGF, IC50=2µM. Enhances self-renewal of embryonic stem cells PD-98059 is an invaluable tool to help elucidate the role of the MAPK cascade in a variety of biological systems. Inhibits cell growth and proliferation in acute myelogenous leukemia cell lines by causing cell arrest.
UOM:
1 * 5 mg
New Product
Numéro de catalogue:
(ENZOBMLEI3130500)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Ikarugamycin inhibits the uptake of oxidized low-density lipoprotein in mouse macrophages. It blocks PMA and Nef-mediated cell surface CD4 down-regulation. Ikarugamycin is emerging as a general inhibitor of clathrin-coated pit-mediated endocytosis and appears to be a useful agent for studying the process of endocytosis.
UOM:
1 * 500 µG
New Product
Numéro de catalogue:
(BOSSBS-1346R-CY5)
Fournisseur:
Bioss
Description:
Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-14082R-A680)
Fournisseur:
Bioss
Description:
Essential factor involved in transcription-coupled nucleotide excision repair which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation. It recruits the CSA complex (DCX(ERCC8) complex), nucleotide excision repair proteins and EP300 to the at sites of RNA polymerase II-blocking lesions.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0792R-HRP)
Fournisseur:
Bioss
Description:
Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
UOM:
1 * 100 µl
Fournisseur:
Biotium
Description:
CF® Dye alkynes react with azide groups via copper-catalysed bioorthogonal cycloaddition. Can be used to fluorescently detect or label azide groups on target molecules. CF® Dye alkynes can also be used as building blocks to form fluorescent polymers.
Numéro de catalogue:
(BOSSBS-5161R-CY7)
Fournisseur:
Bioss
Description:
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
UOM:
1 * 100 µl
Fournisseur:
ENZO LIFE SCIENCES
Description:
Selective prostaglandin E₂ receptor (EP₁) antagonist. Useful at concentrations up to 10 µM, at which point it starts to block PGD₂ and TXA₂ receptors.
Numéro de catalogue:
(BOSSBS-0738R-A750)
Fournisseur:
Bioss
Description:
Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
UOM:
1 * 100 µl
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est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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