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block+heaters+
Fournisseur:
OZ BIOSCIENCES
Description:
Helix-IN™ DNA transfection reagent opens up new possibilities for addressing issues of classical transfection technologies. Helix-IN™ is a patented Cationic Hydroxylated Amphiphilic Multi-block Polymer (CHAMP™ Technology). This novel bi-functional co-polymer is biocompatible, ionisable, pH responsive
Numéro de catalogue:
(PRSI76-374)
Fournisseur:
ProSci Inc.
Description:
The RM4-5 monoclonal antibody specifically reacts with mouse CD4, also known as L3T4, a 55 kDa differentiation antigen expressed by the majority of thymocytes, subpopulations of mature T cells (like major histocompatibility complex class II-restricted T lymphocytes), a subset of natural killer T cells, and on pluripotent hematopoietic stem cells. CD4 binds to the major histocompatibility complex class II (MHC class II) and enhances T lymphocyte development and mature T cells functions. In T lymphocytes, CD4 binds to the cytoplasmic tail of enzyme tyrosine kinase (p56lck).Binding of RM4-5 is blocked by the anti-mouse CD4 clone GK1.5.
UOM:
1 * 0,5 mg
New Product
Numéro de catalogue:
(PRSI2413)
Fournisseur:
ProSci Inc.
Description:
Aven Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Aven is a recently discovered protein that blocks apoptosis induced by Apaf-1 and caspase-9. It is thought that Aven functions by binding to Bcl-xL, an antiapoptotic member of the Bcl-2 family, and to Apaf-1, possibly interfering with the ability of Apaf-1 to self-associate, suggesting that Aven impedes Apaf-1-mediated caspase activation. Higher levels of Aven mRNA are seen in patients with acute leukemia than in control patients, suggesting that Aven may be useful as a prognostic indicator in leukemia patients.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI76-508)
Fournisseur:
ProSci Inc.
Description:
The PC61.5 antibody specifically reacts with mouse CD25, the 55 kDa low-affinity Interleukin-2 Receptor alpha chain (IL-2R alpha), expressed on early progenitors of T and B lineage, and on B and T cells. Together with CD122 (IL-2 Receptor beta) and CD 132 (IL-2 Receptor gamma c, the common gamma chain), CD25 forms high-affinity receptor complexes for IL-2. Resting B and T cells and natural killer cells do not express IL-2R alpha. Cd25 is also expressed on the dendritic cells, and it enhances lymphocyte differentiation and activation.The PC61.5 antibody block the binding of IL-2 to both high-affinity and low-affinity receptors.
UOM:
1 * 0,5 mg
New Product
Numéro de catalogue:
(PRSI7069)
Fournisseur:
ProSci Inc.
Description:
BATF Antibody: BATF is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events and blocks cellular transformation by Ras and Fos. BATF also is required for the differentiation of IL-17-producing T helper (TH17) cells, a CD4+ subset of T cells that coordinates the inflammatory response in host defense. In both T cells and B cells, BATF is required for the appropriate regulation of the class-switch recombination.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI90-381)
Fournisseur:
ProSci Inc.
Description:
CCL4, (C-C motif chemokine 4; macrophage inflammatory protein 1beta) is a chemokine secreted at sites of inflammation by activated leukocytes, lymphocytes, vascular endothelial cells and pulmonary smooth cells. CCL4 attracts a variety of immune cells to sites of microbial infection as well as to pathologic inflammation, such as allergic asthma and ischemic myocardium. Full-length and truncated CCL4 exert biological activity through the receptor CCR5. The truncated form of CCL4 interacts additionally with CCR1 and CCR2b. The ability of CCL4 to bind CCR5 inhibits the cellular entry of M-tropic HIV. Both CCL4 forms block HIV-1 infection of T cells by inducing the downregulation of CCR5.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-300)
Fournisseur:
ProSci Inc.
Description:
CD55 is a member of the RCA (regulators of complement activation) family. RCA proteins is characterized by the presence of four to 30 SCRs (short consensus repeats also called CCPs for control protein modules) in their plasmaexposed regions. CD55 containing four SCR modules is involved in the regulation of the complement cascade. CD55 is known to bind CD97 via the first SCR. It also binds physiologically generated C3 convertases with its second and third SCRs. Binding results in an accelerated “decay”, or dissociation of active C3 convertases, thus blocking the development of C’ attack complexes on nonforeign cells. It is known that viruses and bacteria also utilize multiple SCR sites for infection.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI33-401)
Fournisseur:
ProSci Inc.
Description:
Recognises an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3 (WS: IV & V). Its epitope localizes in the D2 extracellular domain and is resistant to neuraminidase and proteases. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signalling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This mAb inhibits primary mixed lymphocyte culture (mlC) but not secondary mlC, cytotoxicity or proliferation induced by mitogens. It blocks binding of NK1-L16 stimulated T cells to L cells expressing CD50. This mAb is excellent for staining of formalin/paraffin tissues.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-339)
Fournisseur:
ProSci Inc.
Description:
Recognises a protein of 210-220 kDa, which is identified as the complement receptor 1 (CR1)/CD35. This mAb does not block CR1 activity. It is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This mAb labels follicular dendritic cells and follicular dendritic cell sarcoma.
UOM:
1 * 1 EA
New Product
Fournisseur:
EPPENDORF
Description:
The Mastercycler® nexus brings the reliability and ease of use of an Eppendorf® cycler at a good price. Low energy consumption, easy extension to 3 units and a small footprint make the Mastercycler® nexus both cost effective and an efficient use of laboratory space. It can handle all kinds of PCR consumables, from low volume up to 0,5 ml PCR tubes. All common PCR plates fit and, if throughput becomes higher, it is possible to connect an additional one or two Mastercycler nexus eco units.
Numéro de catalogue:
(MDTC61-242-RG)
Fournisseur:
Corning
Description:
Le chlorhydrate (HCl) de tétracycline est un antibiotique qui inhibe la synthèse des protéines en se liant à la sous-unité ribosomale 30S, bloquant ainsi les interactions sur le site accepteur du complexe RBA-ribosome. C'est un membre de la famille d'antibiotiques des tétracyclines, une classe à large spectre qui inhibe par un mécanisme courant la croissance des organismes aérobies et anaérobies. Les congénères de la tétracycline sont obtenus de façon semi-synthétique à partir de la chlortétracycline produite par Staphylococcus aureofaciens. Sa résistance est conférée par le produit du gène TetR-Tn10 qui bloque la perméabilité de la paroi cellulaire. Le HCl de tétracycline est efficace contre les bactéries à Gram positif et à Gram négatif et est proposé sous forme de poudre.
UOM:
1 * 5 g
Numéro de catalogue:
(PRSI76-378)
Fournisseur:
ProSci Inc.
Description:
The RM4-5 monoclonal antibody specifically reacts with mouse CD4, also known as L3T4, a 55 kDa differentiation antigen expressed by the majority of thymocytes, subpopulations of mature T cells (like major histocompatibility complex class II-restricted T lymphocytes), a subset of natural killer T cells, and on pluripotent hematopoietic stem cells. CD4 binds to the major histocompatibility complex class II (MHC class II) and enhances T lymphocyte development and mature T cells functions. In T lymphocytes, CD4 binds to the cytoplasmic tail of enzyme tyrosine kinase (p56lck).Binding of RM4-5 is blocked by the anti-mouse CD4 clone GK1.5.
UOM:
1 * 0,025 mg
New Product
Numéro de catalogue:
(PRSI76-139)
Fournisseur:
ProSci Inc.
Description:
The M17/4 monoclonal antibody specifically reacts with mouse CD11a, a 180 kDa glycoprotein. CD11a is the integrin alpha L chain that forms with CD18 the heterodimer molecule Lymphocyte Function-associated Antigen-1 (LFA-1). LFA-1 is expressed on all leukocytes and is involved in intercellular adhesions. The M17/4 antibody blocks many of the LFA-1 mediated cell interaction and in vivo it prolongs allograft survival, inhibits the autoimmune response, and reduces graft versus host reactions.
UOM:
1 * 0,05 mg
New Product
Numéro de catalogue:
(PRSI76-574)
Fournisseur:
ProSci Inc.
Description:
The 2.4G2 monoclonal antibody specifically reacts with an epitope on the extracellular domain of the mouse CD16 (Fc gamma III) and CD 32 (Fc gamma II). CD16 and CD32 are low affinity receptors for the IgG Fc domain and are expressed by B lymphocytes, NK cells, kupffer cells, mast cells, monocytes, macrophages, granulocytes, immature thymocytes, neutrophils, and some activated mature T cells.The 2.4G2 antibody blocks the binding of immunoglobulins to CD16 and CD32, and possibly to Fc gamma I receptor.
UOM:
1 * 0,5 mg
New Product
Numéro de catalogue:
(PRSI76-519)
Fournisseur:
ProSci Inc.
Description:
The PC61.5 antibody specifically reacts with mouse CD25, the 55 kDa low-affinity Interleukin-2 Receptor alpha chain (IL-2R alpha), expressed on early progenitors of T and B lineage, and on B and T cells. Together with CD122 (IL-2 Receptor beta) and CD 132 (IL-2 Receptor gamma c, the common gamma chain), CD25 forms high-affinity receptor complexes for IL-2. Resting B and T cells and natural killer cells do not express IL-2R alpha. Cd25 is also expressed on the dendritic cells, and it enhances lymphocyte differentiation and activation.The PC61.5 antibody block the binding of IL-2 to both high-affinity and low-affinity receptors.
UOM:
1 * 0,1 mg
New Product
Numéro de catalogue:
(PRSI76-514)
Fournisseur:
ProSci Inc.
Description:
The PC61.5 antibody specifically reacts with mouse CD25, the 55 kDa low-affinity Interleukin-2 Receptor alpha chain (IL-2R alpha), expressed on early progenitors of T and B lineage, and on B and T cells. Together with CD122 (IL-2 Receptor beta) and CD 132 (IL-2 Receptor gamma c, the common gamma chain), CD25 forms high-affinity receptor complexes for IL-2. Resting B and T cells and natural killer cells do not express IL-2R alpha. Cd25 is also expressed on the dendritic cells, and it enhances lymphocyte differentiation and activation.The PC61.5 antibody block the binding of IL-2 to both high-affinity and low-affinity receptors.
UOM:
1 * 0,025 mg
New Product
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est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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