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Numéro de catalogue: (BOSSBS-2789R-A680)

Fournisseur:  Bioss
Description:   Involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. Also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. Inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. Inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP1 and prevents the conformational rearrangement of TAP induced by peptide binding. Inhibited by human adenovirus E3-19K glycoprotein, which binds the TAP complex and acts as a tapasin inhibitor, preventing MHC class I/TAP association. Expression of TAP1 is down-regulated by human Epstein-Barr virus vIL-1 protein, thereby affecting the transport of peptides into the endoplasmic reticulum and subsequent peptide loading by MHC class I molecules.
UOM:  1 * 100 µl
Fournisseur:  ENZO LIFE SCIENCES
Description:   Blocks lipid peroxidation
UOM:  1 * 100 mg
New Product

Fournisseur:  Bioss
Description:   After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-1049R-A750)

Fournisseur:  Bioss
Description:   After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-0792R-A680)

Fournisseur:  Bioss
Description:   Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-0792R-A647)

Fournisseur:  Bioss
Description:   Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-8191R-A750)

Fournisseur:  Bioss
Description:   Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-6625R)

Fournisseur:  Bioss
Description:   Insig2 is highly similar to the protein product encoded by gene Insig1. Both Insig1 protein and Insig2 protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-0792R-CY7)

Fournisseur:  Bioss
Description:   Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
UOM:  1 * 100 µl
Numéro de catalogue: (NOVUNB300-511)

Fournisseur:  Novus Biologicals
Description:   The CFTR Antibody (CF3) from Novus Biologicals is a mouse monoclonal antibody to CFTR. This antibody reacts with human, mouse, rat, chicken. The CFTR Antibody (CF3) has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Blocking/Neutralising.
UOM:  1 * 100 µl
New Product
Numéro de catalogue: (BOSSBS-0792R-A350)

Fournisseur:  Bioss
Description:   Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-0792R-A750)

Fournisseur:  Bioss
Description:   Tumor suppressor. It blocks the growth, invasion and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-1346R-CY5.5)

Fournisseur:  Bioss
Description:   Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth (By similarity). Overexpression of HYAL1 suppressed the growth rate of colon carcinoma cell tumors in an experimental model.
UOM:  1 * 100 µl
Fournisseur:  Cayman Chemical
Description:   Lamotrigine is an inhibitor of voltage-gated sodium channels (Na<sub>v</sub>), blocking human Na<sub>v</sub>1,2, Na<sub>v</sub>1,5, and Na<sub>v</sub>1,8 with IC<sub>50</sub> values of 10, 62, and 96 μM, respectively.
Numéro de catalogue: (BOSSBS-0492R-CY3)

Fournisseur:  Bioss
Description:   Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. May play a role in leukemogenesis. Plays a role in negative feedback control pathway for adenylyl cyclase signaling. Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein.
UOM:  1 * 100 µl
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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'call est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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