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capillary+tubes+fittings
Numéro de catalogue:
(PRSI4557)
Fournisseur:
ProSci Inc.
Description:
Ambra1 Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. Beclin-1, a principal regulator of autophagosome formation, is in turn regulated by Ambra1. Ambra1 associates with Beclin-1 through a region near its center as determined by yeast two-hybrid assay. Null mutations in this gene in mice resulted in embryonic lethality with severe neural tube defects associated with autophagy impairment, accumulation of ubiquitinated proteins, unbalanced cell proliferation and excessive apoptotic death. Furthermore, down-regulation of Ambra1 in cultured cells though RNA interference decreased the level of rapamycin- and nutrient starvation-induced autophagy. Multiple isoforms of Ambra1 are known to exist.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI33-765)
Fournisseur:
ProSci Inc.
Description:
PAX-8 is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical thyroid adenomas. PAX-8 is expressed in the thyroid (and associated carcinomas), non-ciliated mucosal cells of the fallopian tubes, and simple ovarian inclusion cysts, but not normal ovarian surface epithelial cells. PAX-8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX-8 expression is reported in renal tubules as well as renal cell carcinoma, nephroblastoma, and seminoma. PAX-8 antibody may be used as an additional immunohistochemical marker for renal epithelial tumors.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-748)
Fournisseur:
ProSci Inc.
Description:
Recognises a protein of ~140 kDa, identified as N-Cadherin (NCAD), also known as CDH2 and CD325. CDH2 is a member of the Cadherin superfamily, and consists of five extracellular repeats, a transmembrane domain and a cytoplasmic domain. CDH2 deficient mice die at day 10 of gestation and embryos display major heart defects and malformed neural tubes and somites. Consistent with this, the protein has been implicated in several aspects of cardiac development including the precardiac mesoderm, establishment of left-right symmetry and cardiac looping morphogenesis. Furthermore, it is normally involved in inducing cell cycle arrest and its expression is frequently deregulated in cancer cells. Studies have linked N-cadherin to cancer metastasis by showing the aggressive tumor cells had preferentially turned on N-cadherin as opposed to E- or P-cadherin.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(KART0094400)
Fournisseur:
KARTELL
Description:
These tips are made of high quality, 100% pure, virgin PP. Made in the highest quality moulds, these tips can be used whenever the work demands a higher standard.
UOM:
1 * 10.000 ST
Numéro de catalogue:
(PRSI4297)
Fournisseur:
ProSci Inc.
Description:
PTK7 Antibody: Protein-tyrosine kinases (PTKs) play important roles in regulating cell proliferation and differentiation during development. One member of the PTK family, PTK7, has been suggested to regulate the planar cell polarity (PCP) pathway in vertebrates and may play a role in neural convergent extension and neural tube closure. PTK7 has also been implicated in the development of cancer. Loss of PTK7 expression was seen in several melanoma cell lines and biopsies. Conversely, high-throughput analysis of acute myeloid leukemia samples showed an increased level of PTK7 expression compared to normal bone marrow and purified CD34+ cells. Multiple isoforms of PTK7 are known to exist.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI4299)
Fournisseur:
ProSci Inc.
Description:
PTK7 Antibody: Protein-tyrosine kinases (PTKs) play important roles in regulating cell proliferation and differentiation during development. One member of the PTK family, PTK7, has been suggested to regulate the planar cell polarity (PCP) pathway in vertebrates and may play a role in neural convergent extension and neural tube closure. PTK7 has also been implicated in the development of cancer. Loss of PTK7 expression was seen in several melanoma cell lines and biopsies. Conversely, high-throughput analysis of acute myeloid leukemia samples showed an increased level of PTK7 expression compared to normal bone marrow and purified CD34+ cells. Multiple isoforms of PTK7 are known to exist.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI92-644)
Fournisseur:
ProSci Inc.
Description:
Mesothelin is a cell surface glycoprotein whose expression is limited to mesothelial cells of the serosa (pleura, pericardium, and peritoneum) and epithelial cells of the trachea, tonsils, fallopian tube, and kidneys. Mesothelin plays an important role in cell survival, proliferation, migration, invasion, tumor progression, and resistance to chemotherapy. The overexpression of mesothelin can activate NF-κB and signal transducer and activator of transcription 3 (Stat3), inhibit apoptotic signaling and TNF- alpha-induced apoptosis, and accelerate the G1–S transition. Mesothelin is also found overexpressed in various cancers, including malignant mesothelioma, pancreatic or ovarian carcinoma, sarcomas and in some gastrointestinal or pulmonary carcinomas. As a result of its limited expression in normal tissues, mesothelin has been reported as an ideal tumor-associated marker for the development of targeted therapy.
UOM:
1 * 50 µG
Numéro de catalogue:
(444-9296)
Fournisseur:
Edmund Bühler GmbH
Description:
Plateau universel KS perforé (430×300 mm), Pour: Portoirs pour tubes à essai ou pinces pour flacons Erlenmeyer et autres récipients**
UOM:
1 * 1 ST
Numéro de catalogue:
(PRSI49-594)
Fournisseur:
ProSci Inc.
Description:
SLIT-1 (also known as KIAA0813, MEGF4, multiple epidermal growth factor-like domains 4 and Slit homolog 1 protein) is a Slit protein. This protein is a ligand for the Roundabout (Robo) receptors and acts as guidance cues in axonal migration/navigation during neural development, at the ventral midline of the neural tube. Slit1 and Slit2 are essential for midline guidance in the forebrain by acting as repulsive signals preventing inappropriate midline crossing by axons projecting from the olfactory bulb. Each SLIT gene encodes a putative secreted protein, which contains conserved protein-protein interaction domains including leucine-rich repeats and epidermal growth factor-like motifs, similar to those of the Drosophila protein. In situ hybridization studies indicated that the rat SLIT-1 mRNA was specifically expressed in the neurons of fetal and adult forebrains. This data suggests that the SLIT genes form an evolutionarily conserved group in vertebrates and invertebrates, and that the mammalian SLIT proteins may participate in the formation and maintenance of the nervous and endocrine systems by protein-protein interactions. Alternative splicing isoforms have been identified for Slit1 protein.
UOM:
1 * 50 µG
Fournisseur:
HEATHROW
Description:
True North® freezer boxes (cryoboxes) were designed with sustainability in mind and are made from a specially formulated corrugated or thin film polypropylene.
Numéro de catalogue:
(HYPE9055-022)
Fournisseur:
Thermo Fisher Scientific
Description:
Sample loop, for 9010, 9725 and 9725i injectors, PEEK, 20 µl, Pour tuyau Ø int.: 0,25 mm
UOM:
1 * 1 ST
Numéro de catalogue:
(391-8326)
Fournisseur:
Thermo Fisher Scientific
Description:
Transport and universal containers have passed the 95 kPa test described in UN packaging instructions 602/650 for transport of infectious substances and diagnostic specimens (except 391-8326). Universal containers are maximum RCF tested (RCF=Relative Centrifugal Force). Caps designed to avoid droplets adhering to the surface giving reduced risk of aerosols.
UOM:
1 * 400 ST
Numéro de catalogue:
(115-0261)
Fournisseur:
BERKSHIRE
Description:
Fabriqués en fils continus 100% polyester tricoté. Tricotés en forme tubulaire et soudés aux deux bords ouverts pour une propreté optimale. Lavés en salle blanche ISO classe 4 (classe 10).
UOM:
1 * 250 ST
Numéro de catalogue:
(510-1997)
Fournisseur:
Retsch GmbH
Description:
Fonds collecteurs avec tube d'écoulement, acier inoxydable, Ø: 400 mm, Hauteur: 70 mm
UOM:
1 * 1 ST
Numéro de catalogue:
(516-0156)
Fournisseur:
Sartorius
Description:
Les filtres à centrifuger Vivaclear sont des filtres unidirectionnels pour une clarification/une filtration rapides et fiables d'échantillons biologiques et biotechnologiques dans une plage de 100 à 500 µl. Ils peuvent être utilisés dans des rotors à angle fixe pour des tubes de 2,2 ml.
UOM:
1 * 100 ST
Fournisseur:
KGW (KARLSRUHER GLASTECHN.)
Description:
Borosilicate glass.
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est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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