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cell+culture+flasks
Numéro de catalogue:
(BOSSBS-11224R-HRP)
Fournisseur:
Bioss
Description:
DNA damage or incomplete replication of DNA results in the inhibition of cell cycle progression at the G1 to S or the G2 to M phase transition by conserved regulatory mechanisms known as cell cycle checkpoints. Checkpoint proteins include Rad17, which is involved in regulating cell cycle progression at the G1 checkpoint as well as Chk1, Chk2, Rad1, Rad9 and Hus1, which are involved in regulating cell cycle arrest at the G2 checkpoint. In response to DNA damage, ATM and ATR kinases are important for cell cycle checkpoint response signalling. ATR-interacting protein (ATRIP), also designated ATM and Rad3-related-interacting protein, is required for checkpoint signaling after DNA damage. It is also important for ATR expression, which regulates DNA replication and damage checkpoint responses. ATRIP is a ubiquitously expressed protein that can form heterodimers with ATR. After dimerization they bind the RPA complex and are recruited to single stranded DNA. ATRIP is a nuclear protein that may also play a role in protein stabilization.
UOM:
1 * 100 µl
Numéro de catalogue:
(ROCK200-526-N79)
Fournisseur:
Rockland Immunochemicals
Description:
Anti-CD11b is useful for Immunoprecipitation, immunochemistry, and Flow Cytometry using mouse spleen cells, or an appropriate cell type (where indicated).
UOM:
1 * 1 EA
Numéro de catalogue:
(BOSSBS-7526R-CY5.5)
Fournisseur:
Bioss
Description:
BTG1 belongs to the BTG family of proteins.FUNCTION: Anti-proliferative protein. Its expression is associated with the early G1 phase of the cell cycle. A chromosomal aberration involving BTG1 may be a cause of a form of B cell chronic lymphocytic leukemia; translocation t(8;12)(q24;q22) with MYC.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-4961R-A555)
Fournisseur:
Bioss
Description:
Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(ENZOBMLSE4130005)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Produced in insect cells.
UOM:
1 * 5 µG
New Product
Numéro de catalogue:
(ENZOBMLCT1040010)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Cell permeable and potent angiogenesis inhibitor from the family of withanolides. Inhibits endothelial cells (HUVEC) sprouting in vitro (IC50=12nM) and in vivo. Exhibits antitumor, anti-inflammatory, radiosensitizing, and immunosuppressive properties. Potently inhibits NF-κB activation by preventing the TNF-induced activation of IκB kinase β (IKKβ). Elicits IKKß hyperphosphorylation concomitant with inhibition of its kinase activity. Affects AP1 transcription and induces cell death. Alters cytoskeletal architecture by covalently binding annexin II and stimulating its basal F-actin cross-linking activity which inhibits the migratory and invasive capability of endothelial cells. Targets the intermediate filament protein vimentin. Displays neuronal regenerative properties. It induced significant regeneration of both axons and dendrites in an A β-induced axonal atrophy model.
UOM:
1 * 10 mg
New Product
Numéro de catalogue:
(BOSSBS-0061R-A647)
Fournisseur:
Bioss
Description:
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-10196R-HRP)
Fournisseur:
Bioss
Description:
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0061R-A750)
Fournisseur:
Bioss
Description:
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(ENZOALX306031M001)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Potent stimulator of NKT cells.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(BOSSBS-4819R-A750)
Fournisseur:
Bioss
Description:
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7508R-A350)
Fournisseur:
Bioss
Description:
Tmtsp is a novel marker gene for primitive hematopoietic cells and endothelial cells. Tmtsp gene is a newly identified cell-surface molecule with thrombospondin domain. Tmtsp antibody would serve as a valuable tool for the analysis of both embryonic and adult hematopoiesis, as well as for vascular biology.Cellular localization: Isoform 1: Membrane; Single-pass type I membrane protein, Isoform 2: Membrane; Single-pass type I membrane protein, Isoform 3: Secreted.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7508R-A750)
Fournisseur:
Bioss
Description:
Tmtsp is a novel marker gene for primitive hematopoietic cells and endothelial cells. Tmtsp gene is a newly identified cell-surface molecule with thrombospondin domain. Tmtsp antibody would serve as a valuable tool for the analysis of both embryonic and adult hematopoiesis, as well as for vascular biology.Cellular localisation: Isoform 1: Membrane; Single-pass type I membrane protein, Isoform 2: Membrane; Single-pass type I membrane protein, Isoform 3: Secreted.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7508R-HRP)
Fournisseur:
Bioss
Description:
Tmtsp is a novel marker gene for primitive hematopoietic cells and endothelial cells. Tmtsp gene is a newly identified cell-surface molecule with thrombospondin domain. Tmtsp antibody would serve as a valuable tool for the analysis of both embryonic and adult hematopoiesis, as well as for vascular biology.Cellular localization: Isoform 1: Membrane; Single-pass type I membrane protein, Isoform 2: Membrane; Single-pass type I membrane protein, Isoform 3: Secreted.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13546R-A488)
Fournisseur:
Bioss
Description:
Stress-activated component of a protein kinase signal transduction cascade. Regulates the JNK and p38 pathways. Pro-apoptotic. Role in regulation of S and G2 cell cycle checkpoint by direct phosphorylation of CHEK2. Isoform 1, but not isoform 2, causes cell shrinkage and disruption of actin stress fibers. Isoform 1 may have role in neoplastic cell transformation and cancer development. Isoform 1, but not isoform 2, phosphorylates histone H3 at 'Ser-28'.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-4212R-A555)
Fournisseur:
Bioss
Description:
Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses (By similarity).
UOM:
1 * 100 µl
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est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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