Protéines et Peptides
Numéro de catalogue:
(PRSI5123P)
Fournisseur:
ProSci Inc.
Description:
ZBED3 peptide is used for blocking the activity of ZBED3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4269P)
Fournisseur:
ProSci Inc.
Description:
Carabin peptide is used for blocking the activity of Carabin antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4275P)
Fournisseur:
ProSci Inc.
Description:
MORF4 peptide is used for blocking the activity of MORF4 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5795P)
Fournisseur:
ProSci Inc.
Description:
ATG3 peptide is used for blocking the activity of ATG3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5805P)
Fournisseur:
ProSci Inc.
Description:
IFITM1 peptide is used for blocking the activity of IFTIM1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5799P)
Fournisseur:
ProSci Inc.
Description:
ATG13 peptide is used for blocking the activity of ATG13 antibody.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI90-398)
Fournisseur:
ProSci Inc.
Description:
CD68 is a single-pass type I membrane protein which belongs to the LAMP family. CD68 is highly expressed by blood monocytes and tissue macrophages. It is also expressed in lymphocytes, fibroblasts and endothelial cells and in many tumour cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites. CD68 plays a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It is a commonly used marker for macrophages. However, a number of studies have shown that CD68 antibodies react with other hematopoietic and non-hematopoietic cell types, suggesting that CD68 may not be a macrophage-specific antigen. CD68 binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI91-608)
Fournisseur:
ProSci Inc.
Description:
Parathyroid hormone 1 receptor(PTH1R) is a multi-pass membrane protein. The protein is expressed in high levels in bone and kidney and regulates calcium ionhomeostasis through activation of adenylate cyclase and phospholipase C. In bone, it is expressed on the surface of osteoblasts. When the receptor is activated through PTH binding, osteoblasts express RANKL (Receptor Activator of Nuclear Factor kB Ligand), which binds to RANK (Receptor Activator of Nuclear Factor kB) on osteoclasts. This turns on osteoclasts to ultimately increase the resorption rate.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-609)
Fournisseur:
ProSci Inc.
Description:
Low affinity immunoglobulin gamma Fc region receptor II (CD32B) is a single-pass type I membrane protein and contains 2 Ig-like C2-type (immunoglobulin-like) domains. The inhibitory CD32B is expressed on B cells and myeloid dendritic cells. Ligation of CD32B on B cells downregulates antibody production and may, in some circumstances, promote apoptosis. Co-ligation of CD32B on dendritic cells inhibits maturation and blocks cell activation. CD32B may also be a target formonoclonal antibody therapy for malignancies.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-251)
Fournisseur:
ProSci Inc.
Description:
DCN1-Like Protein 1 is a protein containing 1 DCUN1 domain and 1 UBA-like domain. DCN1-Like Protein 1 contains part of an E3 Ubiquitin Ligase Complex for Neddylation. It is required for Neddylation of Cullin components of E3 Cullin-RING Ubiquitin Ligase complexes. It enhances the rate of Cullins Neddylation. DCN1-Like Protein 1 recruits the NEDD8-charged E2 Enzyme to the Cullin component. DCUN1D1 is involved in the release of inhibitory effects of CAND1 on the Cullin-RING Ligase E3 complex assembly and activity. It acts also as an oncogene facilitating malignant transformation and carcinogenic progression.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-573)
Fournisseur:
ProSci Inc.
Description:
Dickkopf-related protein 1(DKK-1), is a member of the dickkopf family. DKK1 secreted proteins with two cysteine-rich domains separated by a linker region. It antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-574)
Fournisseur:
ProSci Inc.
Description:
Tumor necrosis factor receptor superfamily member 1A (Tnfrsf1a) is a member of the tumor necrosis factor receptor superfamily. Tnfrsf1a is one of the major receptors for the tumor necrosis factor-alpha. It can activate the transcription factor NF-κB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the human genetic disorder called tumor necrosis factor associated periodic syndrome (TRAPS) or periodic fever syndrome
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-621)
Fournisseur:
ProSci Inc.
Description:
FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family.The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. They act on several cell types to regulate diverse physiologic functions including angiogenesis, cell growth, pattern formation, embryonic development, metabolic regulation, cell migration, neurotrophic effects, and tissue repair. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-606)
Fournisseur:
ProSci Inc.
Description:
Brother of CDO is a protein that in humans is encoded by the BOC gene. CDON and BOC are cell surface receptors of the immunoglobulin (Ig)/fibronectin type III repeat family involved in myogenic differentiation. CDON and BOC are coexpressed during development, form complexes with each other in a cis fashion, and are related to each other in their ectodomains, but each has a unique long cytoplasmic tail.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4781P)
Fournisseur:
ProSci Inc.
Description:
IL-34 peptide is used for blocking the activity of IL-34 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6303P)
Fournisseur:
ProSci Inc.
Description:
SPT1 peptide is used for blocking the activity of SPT1 antibody.
UOM:
1 * 50 µG
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