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Protéines et Peptides
Numéro de catalogue:
(PRSI90-475)
Fournisseur:
ProSci Inc.
Description:
Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma, and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts numerous effects on various hematopoietic cell types. On B cells, IL-4 promotes immunoglobulin class switching to IgE and IgG1 isotypes and upregulates MHC class II and CD23 expression. IL-4 promotes survival, growth, and differentiation of both T and B lymphocytes, mast cells and endothelial cells. In addition, IL-4 inhibits the production of TNF, IL-1, and IL-6 by macrophages.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-489)
Fournisseur:
ProSci Inc.
Description:
Interleukin-7 (IL-7), is a hematopoietic growth factor and a member of the IL-7/IL-9 family. IL-7 stimulates the proliferation of lymphoid progenitors and is secreted by stromal cells in the bone marrow and thymus. IL-7 is also important for proliferation during certain stages of B cell maturation. IL-7 and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. It is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRbeta) during early T cell development. IL-7 can be produced locally by intestinal epithelial and epithelial goblet cells and may serve as a regulatory factor for intestinal mucosal lymphocytes.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3151P)
Fournisseur:
ProSci Inc.
Description:
PHAP I peptide is used for blocking the activity of PHAP I antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3145P)
Fournisseur:
ProSci Inc.
Description:
PHAP I peptide is used for blocking the activity of PHAP I antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3139P)
Fournisseur:
ProSci Inc.
Description:
TLR4 peptide is used for blocking the activity of TLR4 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3171P)
Fournisseur:
ProSci Inc.
Description:
PARC peptide is used for blocking activity of PARC antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-405)
Fournisseur:
ProSci Inc.
Description:
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3 (CEACAM3) belongs to the immunoglobulin superfamily and CEA family. CEACAM3 was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. CEACAM3 mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. In addition, it is associated with the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-239)
Fournisseur:
ProSci Inc.
Description:
Protein SCO1 Homolog, Mitochondrial (SCO1) is a member of the SCO1/2 family. SCO1 has a homodimer structure. SCO1 is located in mitochondrion and is highly expressed in muscle, heart, and brain. It is characterized by high rates of Oxidative Phosphorylation (OxPhos). SCO1 is thought to play a important role in cellular copper homeostasis, mitochondrial redox signaling and insertion of copper into the active site of COX. The defects of SCO1 can result in Mitochondrial Complex IV Deficiency (MT-C4D). A disorder of the mitochondrial respiratory chain has heterogeneous clinical manifestations, ranging from isolated myopathy to severe multisystem disease affecting several tissues and organs.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4345P)
Fournisseur:
ProSci Inc.
Description:
CDNF peptide is used for blocking the activity of CDNF antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-383)
Fournisseur:
ProSci Inc.
Description:
CCL5, also known as RANTES (Regulated upon Activation Normal T cell Expressed and Secreted), is an 8kDa β-chemokine that plays a primary role in the inflammatory immune response by means of its ability to attract and activate leukocytes. Human and mouse RANTES exhibit cross-species activity on human and mouse cells. CCL5 is secreted by many cell types at inflammatory sites and it exerts a wide range of activities through the receptors CCR1, CCR3, CCR4 and CCR5. In humans, CCR5 binding to CCL5 inhibits the infectivity of R5 (M-tropic) but not X4 (T-tropic) strains of HIV-1. The deposition of CCL5 on activated vascular endothelial cells is crucial for monocyte adhesion to damaged vasculature, but CCL5 oligomerisation is not required for the extravasation of adherent leukocytes. CCL5 is upregulated in breast cancer and promotes tumour progression through the attraction of proinflammatory macrophages in addition to its actions on tumour cells, stromal cells and the vasculature.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5869P)
Fournisseur:
ProSci Inc.
Description:
AFP peptide is used for blocking the activity of AFP antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5857P)
Fournisseur:
ProSci Inc.
Description:
ATP11B peptide is used for blocking the activity of ATP11B antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5795P)
Fournisseur:
ProSci Inc.
Description:
ATG3 peptide is used for blocking the activity of ATG3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5805P)
Fournisseur:
ProSci Inc.
Description:
IFITM1 peptide is used for blocking the activity of IFTIM1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5799P)
Fournisseur:
ProSci Inc.
Description:
ATG13 peptide is used for blocking the activity of ATG13 antibody.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI91-515)
Fournisseur:
ProSci Inc.
Description:
CMRF35-Like Molecule 9 (CD300LG) is a single-pass type I membrane protein which belongs to the CD300 family. CD300LG has one Ig-like V-type domain which mediates binding to lymphocyte. CD300LG is highly expressed in heart, skeletal muscle and placenta. CD300LG acts as a receptor which may mediate L-selectin-dependent lymphocyte rollings. CD300LG also binds SELL in a calcium dependent manner and lymphocyte. CD300LG may play a important role in molecular traffic across the capillary endothelium.
UOM:
1 * 50 µG
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