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Protéines et Peptides
Numéro de catalogue:
(PRSI1139P)
Fournisseur:
ProSci Inc.
Description:
DR4 peptide is used for blocking the activity of DR4 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-157)
Fournisseur:
ProSci Inc.
Description:
Thioredoxin-Dependent Peroxide Reductase Mitochondrial (PRDX3) is an enzyme that belongs to the AhpC/TSA family. Human and mouse PRDX3 genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Human PRDX3 protein has an antioxidant function and is localised in the mitochondrion. PRDX3 is involved in redox regulation of the cell. PRDX3 protects radical-sensitive enzymes from oxidative damage by a radical-generating system. It acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-164)
Fournisseur:
ProSci Inc.
Description:
Ubiquitin-Conjugating Enzyme E2 Z (ZUBE2Z) is a member of the E2 ubiquitin-conjugating enzyme family. ZUBE2Z is widely expressed in many tissues, with high expression found in the placenta, pancreas, spleen, and testis. It is ubiquitinates proteins that catalyze the covalent attachment of ubiquitin to other proteins. It has shown that ZUBE2Z participate in signalling pathways, and may be involved in apoptosis regulation.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7105P)
Fournisseur:
ProSci Inc.
Description:
TDRG1 Peptide is used for blocking the activity of TDRG1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5401P)
Fournisseur:
ProSci Inc.
Description:
SKA1 peptide is used for blocking the activity of SKA1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5395P)
Fournisseur:
ProSci Inc.
Description:
Prosapip1 peptide is used for blocking the activity of Prosapip1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5407P)
Fournisseur:
ProSci Inc.
Description:
RWDD3 peptide is used for blocking the activity of RWDD3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-316)
Fournisseur:
ProSci Inc.
Description:
The CD70 is a cytokine that belongs to the tumour necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-522)
Fournisseur:
ProSci Inc.
Description:
Mouse Interleukin 36 beta (IL-36B)is a member of the IL-1 family of proteins. It is a cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signalling pathways in target cells linked to a pro-inflammatory response. IL-36B is synthesised in several cells including resting and activated monocytes, and B cells. The receptor for IL-36 beta is thought to be a combination of IL-1 Rrp2 and IL-1 RAcP. Interleukin 36 beta is one part of the IL-36 signalling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP. Interleukin 36 beta are involved in a number of fundamental biological processes such as stimulating production of interleukin-6 and interleukin-8 in synovial fibrobasts, articular chondrocytes and mature adipocytes, inducing expression of a number of antimicrobial peptides including beta-defensin 4 and beta-defensin 103 as well as a number of matrix metalloproteases , inducing the production of proinflammatory cytokines in bone marrow-derived dendritic cells (BMDCs), including IL-12, Il-1 beta, IL-6, TNF-alpha and IL-23, and activating p38 MAPK phosphorylation in BMDCs.Moreover, interleukin 36 beta may be involved in skin inflammatory response by acting on keratinocytes, dendritic cells, and indirectly on T cells to drive tissue infiltration, cell maturation and cell proliferation. It plays an important role in dendritic cell maturation by stimulating the surface expression of CD80, CD86 and MHC class II and inducing the production of IFN-gamma, IL-4 and IL-17 by T helper 1 (Th1) cells, cultured CD4+ T cells and splenocytes.
UOM:
1 * 50 µG
Fournisseur:
SEQENS
Description:
SEQENS IVD manufactures Bovine Serum Albumin (BSA) derived from plasma, collected from healthy animals of French origin. This product is obtained by 'Heat Shock' method, which ensures higher purity and preserves BSA intrinsic properties.
Fournisseur:
SEQENS
Description:
SEQENS IVD manufactures Bovine Serum Albumin (BSA) derived from plasma, collected from healthy animals of French origin. This product is obtained by 'Heat Shock' method, which ensures higher purity and preserves BSA intrinsic properties.
Numéro de catalogue:
(PRSI91-321)
Fournisseur:
ProSci Inc.
Description:
Fibronectin Leucine Rich Transmembrane Protein 1 (FLRT1) is a member of the Fibronectin Leucine Rich Transmembrane protein (FLRT) family. There are three fibronectin leucine-rich repeat transmembrane (FLRT) proteins: FLRT1, FLRT2 and FLRT3, all contain 10 leucine-rich repeats (LRR), a type III fibronectin (FN) domain, followed by the transmembrane region, and a short cytoplasmic tail. FLRT proteins have dual properties as regulators of cell adhesion and potentiators of fibroblast growth factor (FGF) mediated signalling. The fibronectin domain of all three FLRTs can bind FGF receptors. This binding is thought to regulate FGF signaling during development. The LRR domains are responsible for both the localization of FLRTs in areas of cell contact and homotypic cell association. FLRT1 is expressed at brain compartmental boundaries. FLRT1 is a target for tyrosine phosphorylation mediated by FGFR1 and implicate a non-receptor Src family kinase (SFK).
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-282)
Fournisseur:
ProSci Inc.
Description:
Activin proteins that belong to the transforming growth factor-beta (TGF- beta ) superfamily, exert their biological actions by binding to heteromeric receptor complexes of type I and type II serine/threonine kinase receptors. On ligand binding, type I and II receptors form a stable complex, resulting in phosphorylation of type I receptors by type II receptors with constitutive kinase activity, and subsequently initiates the activation of downstream molecules including the endogenous Smads. ActRIIB, also known as ActRIIB, is a type II receptor containing an extracellular domain (ECD), a transmembrane segment, and a cytoplasmic region that includes the kinase domain. ActRIIB is a receptor for activin A, activin B and inhibin A. Multiple ActRIIB isoforms can also be generated, which bind activin isoforms with different affinities.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-280)
Fournisseur:
ProSci Inc.
Description:
There exists two types of tryptophanyl tRNA synthetases, the cytoplasmic form called WARS, the mitochondrial form called WARS2. WARS catalyzes the aminoacylation of tRNA (trp) with tryptophan and is induced by interferon. WARS regulates ERK, Akt, eNOS activation pathway, which are related with angiogenesis, cytoskelatal reorganization and shear stess-reponsive gene expression.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-292)
Fournisseur:
ProSci Inc.
Description:
Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain and a PTB-signaling motif in cytoplasmic domain. CD200R1 and CD200 associate via their respective N-terminal Ig-like domains. CD200R1 is restricted primarily to mast cells, basophils, macrophages, and dendritic cells. It propagates inhibitory signals despite its lacking a cytoplasmic ITIM (immunoreceptor tyrosinebased inhibitory motif). The receptor-substrate interaction may function as a myeloid downregulatory signal.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI2345P)
Fournisseur:
ProSci Inc.
Description:
TP1 peptide is used for blocking the activity of TP1 antibody.
UOM:
1 * 50 µG
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