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Protéines et Peptides
Numéro de catalogue:
(PRSI6927P)
Fournisseur:
ProSci Inc.
Description:
RAB21 peptide is used for blocking the activity of RAB21 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5199P)
Fournisseur:
ProSci Inc.
Description:
MC4R peptide is used for blocking the activity of MC4R antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6941P)
Fournisseur:
ProSci Inc.
Description:
FAM193B peptide is used for blocking the activity of FAM193B antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-187)
Fournisseur:
ProSci Inc.
Description:
Annexin A6 (ANAX6) belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Annexin A6 is a secreted protein and locates on the cell surface. Annexin A6 contains 8 annexin repeats separated by linking sequences of variable lengths. A pair of annexin repeats may form one binding site for calcium and phospholipid. ANXA6 is involved in the regulation of the release of Ca2+ from intracellular stores and may be associated with CD21. In addition, ANXA6 has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-548)
Fournisseur:
ProSci Inc.
Description:
The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific recognition of phosphatidylserine (PtdSer), exposed on the surface of apoptotic cells. Tim-3, a type I transmembrane protein, contains an immunoglobulin and a mucin-like domain in its extracellular portion and a tyrosine phosphorylation motif in its cytoplasmic portion. TIM-3 is preferentially expressed on Th1 and Tc1 cells, and generates an inhibitory signal resulting in apoptosis of Th1 and Tc1 cells. TIM-3 is also expressed on some dendritic cells and can mediate phagocytosis of apoptotic cells and cross-presentation of antigen. Tim-3 functions to inhibit aggressive Th1-mediated auto- and alloimmune responses. Tim-3 pathway blockade by administration of Tim-3:Fc fusion protein accelerated diabetes in nonobese diabetic mice, caused hyperproliferation of Th1 cells and Th1 cytokine release in an experimental autoimmune encephalomyelitis (EAE) model and prevented acquisition of transplantation tolerance induced by costimulation blockade.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI90-552)
Fournisseur:
ProSci Inc.
Description:
Mouse T cell immunoglobulin and mucin domain-containing protein 4, also known as T cell membrane protein 4, TIMD4 and TIM4 is a single-pass type I membrane protein which belongs to the immunoglobulin superfamily and TIM family. TIM4 contains one Ig-like V-type (immunoglobulin-like) domain. It is expressed on dendritic cells and macrophages. TIM4 plays an important role in the proliferation of T helper type 2 (Th2) cells. TIM4 is involved in regulating T cell proliferation and lymphotoxin signalling. It is a ligand for HAVCR1 / TIMD1. The expression of TIM4 in fibroblasts enhanced their ability to engulf apoptotic cells. TIM4 and TIM1 are phosphatidylserine receptors for the engulfment of apoptotic cells and may also be involved in intercellular signalling in which exosomes are involved. Modulation of TIM4 production in dendritic cells (DCs) represents a novel therapeutic approach for the treatment of peanut allergy.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5521P)
Fournisseur:
ProSci Inc.
Description:
TMEM38A peptide is used for blocking the activity of TMEM38A antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-427)
Fournisseur:
ProSci Inc.
Description:
Interleukin 1 receptor-like 1 (IL1RL1) is also known as ST2, DER4, FIT-1, IL33R, ST2L, ST2V, which belongs to the interleukin-1 receptor family. IL1RL1 contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RL1 is receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL1RL1 possibly involved in helper T-cell function. IL1RL1 can interact with MYD88, IRAK1, IRAK4, and TRAF6.
UOM:
1 * 200 µG
Numéro de catalogue:
(PRSI5647P)
Fournisseur:
ProSci Inc.
Description:
Slc37A2 peptide is used for blocking the activity of Slc37A2 antibody.
UOM:
1 * 50 µG
Fournisseur:
SEQENS
Description:
SEQENS IVD manufactures Bovine Serum Albumin (BSA) derived from plasma, collected from healthy animals of French origin. This product is obtained by 'Heat Shock' method, which ensures higher purity and preserves BSA intrinsic properties.
Numéro de catalogue:
(PRSI96-705)
Fournisseur:
ProSci Inc.
Description:
Stathmin (STMN1), a member of the stathmin family, is also known as Leukemia-associated phosphoprotein p18, Oncoprotein 18 (Op18), Phosphoprotein p19 (pp19), Protein Pr22 and pp17, which contains one SLD (stathmin-like) domain. The function of STMN1 as an important regulatory protein of microtubule dynamics has been well-characterized. Stathmin (STMN1) interacts with two molecules of dimeric α,β-tubulin to form a tight ternary complex called the T2S complex.One mole of STMN1 binds to two moles of tubulin dimers through the stathmin-like domain (SLD).When STMN1 sequesters tubulin into the T2S complex, tubulin becomes non-polymerizable. Without tubulin polymerisation, there is no microtubule assembly.STMN1 also promotes microtubule disassembly by acting directly on the microtubule ends.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI96-691)
Fournisseur:
ProSci Inc.
Description:
Sialic acid-binding Ig-like lectin 5 (SIGLEC5) is also known as CD33 antigen-like 2 (CD33L2), Obesity-binding protein 2 (OB-BP2), CD antigen CD170, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. SIGLEC5 / CD170 is expressed by monocytic / myeloid lineage cells. SIGLEC-5 / CD33-L2 binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI1170P)
Fournisseur:
ProSci Inc.
Description:
Bonzo peptide is used for blocking the activity of Bonzo antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI1161P)
Fournisseur:
ProSci Inc.
Description:
FLIP peptide is used for blocking the activity of FLIP antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI1166P)
Fournisseur:
ProSci Inc.
Description:
DR3 peptide is used for blocking the activity of DR3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7199P)
Fournisseur:
ProSci Inc.
Description:
19 amino acids near the carboxy terminus of human PDGF-B.
UOM:
1 * 50 µG
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