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Bioss
Numéro de catalogue:
(BOSSBS-15544R-A555)
Fournisseur:
Bioss
Description:
IER2.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-15315R-A647)
Fournisseur:
Bioss
Description:
C9orf142 (chromosome 9 open reading frame 142) is a 204 amino acid protein that exists as two alternatively spliced isoforms. The gene encoding C9orf142 maps to human chromosome 9q34.3. Chromosome 9 consists of about 145 million bases, represents 4% of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterised by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3428R-A555)
Fournisseur:
Bioss
Description:
Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7612R-A555)
Fournisseur:
Bioss
Description:
HIPK4
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7612R-A647)
Fournisseur:
Bioss
Description:
HIPK4
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2602R-A350)
Fournisseur:
Bioss
Description:
Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2602R-CY7)
Fournisseur:
Bioss
Description:
Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2602R-HRP)
Fournisseur:
Bioss
Description:
Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6533R-A350)
Fournisseur:
Bioss
Description:
Estrogen-induced gene 121 protein may play a role as a marker of hyperestrogenic state and estrogen-related type I endometrial carcinoma. It belongs to the UPF0577 family.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2602R-A680)
Fournisseur:
Bioss
Description:
Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6531R-HRP)
Fournisseur:
Bioss
Description:
SKALP
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1208R-A750)
Fournisseur:
Bioss
Description:
Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. Has angiogenic inhibitor activity (By similarity). Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8571R-A647)
Fournisseur:
Bioss
Description:
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-4816R-CY7)
Fournisseur:
Bioss
Description:
The CD3 complex mediates signal transduction.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8056R-CY5)
Fournisseur:
Bioss
Description:
KLHL14 is a member of the KLHL family. The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown for one member that it is related to Galactose Oxidase for which a structure has been solved. Two isoforms of this protein exist - 70kDa and 43kDa.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8054R-A680)
Fournisseur:
Bioss
Description:
May be a substrate-specific adapter of a CUL3-based E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins during spermatogenesis.
UOM:
1 * 100 µl
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