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Fournisseur:  Bioss
Description:   Component of the NALCN sodium channel complex, a cation channel activated either by neuropeptides substance P or neurotensin that controls neuronal excitability.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-5101R-CY7)

Fournisseur:  Bioss
Description:   MFAP3L is a membrane protein that is highly expressed in testis. It contains 1 Ig-like C2-type (immunoglobulin-like) domain and has three named isoforms produced by alternative splicing. Its function remains unknown.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-10050R-A350)

Fournisseur:  Bioss
Description:   Infectious bursal disease (IBD) is caused by infectious bursal disease virus (IBDV) an avian Birnavirus first described in the USA near the town of Gumboro Delaware and thus the disease is also known as Gumboro disease. There are 3 recognized pathogenic types of IBDV; classic virulent (cvIBDV), sub-clinical (scIBDV), and very virulent (vvIBDV). All three pathogenic types of IBDV cause immune suppression which leads to secondary infections and a failure to produce an immune response to vaccines. The cvIBDV typically cause a high morbidity and low mortality disease while the scIBDV cause very little morbidity and no mortality. The vvIBDV cause an acute disease in chickens characterized by high morbidity and high mortality.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-1004R-CY5.5)

Fournisseur:  Bioss
Description:   Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-10050R-CY5)

Fournisseur:  Bioss
Description:   Infectious bursal disease (IBD) is caused by infectious bursal disease virus (IBDV) an avian Birnavirus first described in the USA near the town of Gumboro Delaware and thus the disease is also known as Gumboro disease. There are 3 recognized pathogenic types of IBDV; classic virulent (cvIBDV), sub-clinical (scIBDV), and very virulent (vvIBDV). All three pathogenic types of IBDV cause immune suppression which leads to secondary infections and a failure to produce an immune response to vaccines. The cvIBDV typically cause a high morbidity and low mortality disease while the scIBDV cause very little morbidity and no mortality. The vvIBDV cause an acute disease in chickens characterized by high morbidity and high mortality.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-10050R-CY3)

Fournisseur:  Bioss
Description:   Infectious bursal disease (IBD) is caused by infectious bursal disease virus (IBDV) an avian Birnavirus first described in the USA near the town of Gumboro Delaware and thus the disease is also known as Gumboro disease. There are 3 recognized pathogenic types of IBDV; classic virulent (cvIBDV), sub-clinical (scIBDV), and very virulent (vvIBDV). All three pathogenic types of IBDV cause immune suppression which leads to secondary infections and a failure to produce an immune response to vaccines. The cvIBDV typically cause a high morbidity and low mortality disease while the scIBDV cause very little morbidity and no mortality. The vvIBDV cause an acute disease in chickens characterized by high morbidity and high mortality.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-8420R-A680)

Fournisseur:  Bioss
Description:   VAT1L.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-5048R-A488)

Fournisseur:  Bioss
Description:   Beta-oxidation of fatty acids. The highest activity concerns the C6 to C10 chain length substrate. Converts the end product of pristanic acid beta oxidation, 4,8-dimethylnonanoyl-CoA, to its corresponding carnitine ester.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-8421R-CY5.5)

Fournisseur:  Bioss
Description:   BOLA1 (BolA-like protein 1), also known as CGI-143, is a member of the BolA/yrbA family of proteins. Members of this family are homologs of the Escherichia coli protein, BolA. BolA-like proteins are evolutionarily conserved from prokaryotes to eukaryotes and are believed to play a role in cell-cycle regulation or cell proliferation possibly via some sort of transcription regulation of other genes. In addition, BolA-like proteins may contain nucleic-acid binding properties, as is suggested by a fold structure that is similar to the KH-fold, a motif known to participate in nucleic-acid binding. Characteristic of BolA-like proteins which typically consist of approximately 100 amino acids, BOLA1 is a 137 amino acid protein.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   APXL is a 1,616 amino acid protein that localizes to a variety of locations within the cell, including the cytoplasm, the cytoskeleton, the cell junction and the apical cell membrane. Containing one ASD1 domain, one ASD2 domain and one PDZ domain, APXL interacts with F-Actin and is thought to mediate endothelial cell morphology during cell spreading, possibly regulating melanosome biogenesis and inducing γ Tubulin redistribution. APXL is expressed in kidney, brain, lung, pancreas and placenta and is overexpressed in melanomas, suggesting a role in tumor transformation and metastasis. The gene encoding APXL maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-12133R-A647)

Fournisseur:  Bioss
Description:   Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family, and is found in a cluster of five alpha subunit genes on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-8421R-A647)

Fournisseur:  Bioss
Description:   BOLA1 (BolA-like protein 1), also known as CGI-143, is a member of the BolA/yrbA family of proteins. Members of this family are homologs of the Escherichia coli protein, BolA. BolA-like proteins are evolutionarily conserved from prokaryotes to eukaryotes and are believed to play a role in cell-cycle regulation or cell proliferation possibly via some sort of transcription regulation of other genes. In addition, BolA-like proteins may contain nucleic-acid binding properties, as is suggested by a fold structure that is similar to the KH-fold, a motif known to participate in nucleic-acid binding. Characteristic of BolA-like proteins which typically consist of approximately 100 amino acids, BOLA1 is a 137 amino acid protein.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-14992R-A750)

Fournisseur:  Bioss
Description:   Family with sequence similarity 3, member D
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-1499R-CY7)

Fournisseur:  Bioss
Description:   Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. May also regulate a network of genes involved in palate development.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-1056R-CY3)

Fournisseur:  Bioss
Description:   G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores. Affects neural activity, perception, cognition and mood. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. May also regulate a network of genes involved in palate development.
UOM:  1 * 100 µl
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