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Bioss
Numéro de catalogue:
(BOSSBS-8423R-CY5)
Fournisseur:
Bioss
Description:
Members of the bactericidal/permeability-increasing protein family have antimicrobial properties and bind lipophilic substances, therefore targeting gram-negative bacteria. The bactericidal permeability increasing protein (BPI) is an antibacterial and endotoxin-neutralizing molecule that is abundant in the granules of polymorphonuclear leukocytes (neutrophil granules). Sharing structural and sequence homologies with BPI, BPIL1 (bactericidal/permeability-increasing protein-like 1) is a 458 amino acid secreted protein that contains the family’s common conserved feature of two cysteine residues that are critical for protein function. While BPIL1 is primarily expressed at low levels in tonsil tissue, it has been found to be upregulated in hypertrophic tonsils, suggesting that it may play a role in the pathogenesis of inflamed disease tissue.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1191R-A488)
Fournisseur:
Bioss
Description:
Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5050R-A555)
Fournisseur:
Bioss
Description:
The CYP39A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of steroids, cholesterol and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-4891R-A647)
Fournisseur:
Bioss
Description:
May have a specific role to play in early thymocyte development.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5050R-CY7)
Fournisseur:
Bioss
Description:
The CYP39A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of steroids, cholesterol and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5049R-A750)
Fournisseur:
Bioss
Description:
Catalyses the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3-25-hydroxylase activity.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-4011R-A555)
Fournisseur:
Bioss
Description:
Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1161R-A647)
Fournisseur:
Bioss
Description:
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1161R-CY5)
Fournisseur:
Bioss
Description:
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8118R-FITC)
Fournisseur:
Bioss
Description:
CCDC147
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-4011R-FITC)
Fournisseur:
Bioss
Description:
Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8119R-FITC)
Fournisseur:
Bioss
Description:
CCDC148 (coiled-coil domain containing 148), also known as MGC125590 or MGC125588, is a 591 amino acid protein encoded by a gene mapping to human chromosome 2. The second largest human chromosome, 2 consists of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstré°‰ syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3909R-A680)
Fournisseur:
Bioss
Description:
Acts together with cubilin to mediate HDL endocytosis (By similarity). May participate in regulation of parathyroid-hormone and para-thyroid-hormone-related protein release.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2171R-CY3)
Fournisseur:
Bioss
Description:
URG4 may be involved in cell cycle progression through the regulation of cyclin D1 expression. It may participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. URG4 may play an important role in development of gastric cancer.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13227R-HRP)
Fournisseur:
Bioss
Description:
FUNDC1 is a 155 amino acid protein belonging to the FUN14 family. The gene encoding FUNDC1 maps to human chromosome Xp11.3 and mouse chromosome X A1.2. The X and Y chromosomes are the human sex chromosomes. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. More than one copy of the X chromosome with a Y chromosome causes Klinefelter's syndrome. A single copy of X alone leads to Turner's syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2171R-A350)
Fournisseur:
Bioss
Description:
URG4 may be involved in cell cycle progression through the regulation of cyclin D1 expression. It may participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. URG4 may play an important role in development of gastric cancer.
UOM:
1 * 100 µl
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