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MP Biomedicals


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Fournisseur:  MP Biomedicals
Description:   Preparation Method: MP Intrinsic Factor is produced from the pylorus mucous membrane of the pig, of which only a small part is used. Only the part which, according to histological examinations has proved to have a high content of Intrinsic Factor, is used.
Applications: Intrinsic Factor is used in the treatment not only of classical pernicious anaemia, but also in the treatment of other macrocytic anaemias, where it replaces the Intrinsic Factor which may be lacking in the patient's own gastric juice. In this way Intrinsic Factor is recommended against anaemias that appear 6 to 12 months after serious gastric operations, and against anaemias that are secondary effects of the treatment with certain medicines, e.g. against epilepsy. However, the dietetic use in multi-vitamin preparations is of the greatest importance. In older people there has been observed a degeneration of the gastric mucous membrane, whose secretion of Intrinsic Factor is insufficient to ensure the resorption of the necessary quantity of B-12 from their diet. In order to delay this development it is useful to prescribe a small quantity of Intrinsic Factor with B-12 and other vitamins to these patients.
Product Description: Intrinsic factor is a glucoprotein extracted from the pylorus part of the gastric mucous membrane. Its presence is considered necessary for the absorption of Vitamin B-12.
Unit Definition: The activity is normally indicated in Coli units, the number of which are proportional to the binding power of the substance to Vitamin B-12.

Application Areas: Absorption of vitamin B12
Product Type: Proteins, Enzymes & Peptides
Presentation: Tan Powder
Foreign activity: Salmonella=Negative, E. coli=Negative
NOTES: Standard Plate Count <1000/g
Solubility: Slightly soluble in toluene; practically insoluble in water.
Storage & Handling: -20°C
Fournisseur:  MP Biomedicals
Description:   β-Sitosterol has recently been shown to induce G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways.
Numéro de catalogue: (ICNA0215671225)

Fournisseur:  MP Biomedicals
Description:   Sulphamethoxypyridazine, en poudre
UOM:  1 * 25 g
Fournisseur:  MP Biomedicals
Description:   Sesame oil is a potent antioxidant, which can inhibit DNA damage and lipid peroxidation by 4-Nitroquinoline N-oxide in rats.
Fournisseur:  MP Biomedicals
Description:   D-myo-INOSITOL (i-Inositol; myo-Inositol; meso-Inositol) A lipotropic agent.
Fournisseur:  MP Biomedicals
Description:   Soluble in water (357 mg/ml at 25 °C; 384 mg/ml at 100 °C), glycerol (100 mg/ml); very slightly soluble in ethanol. Solubility in water is decreased by HCl; almost insoluble in concentrated HCl. Aqueous solutions are at a neutral pH (6,7 to 7,3). Aqueous solutions of sodium chloride are stable at room temperature.
Numéro de catalogue: (ICNA08681001)

Fournisseur:  MP Biomedicals
Description:   Anti-Human Prothrombin Goat Polyclonal Antibody
UOM:  1 * 2 mL
Numéro de catalogue: (ICNA08980641)

Fournisseur:  MP Biomedicals
Description:   This antibody diluent is compatible with common stabilising compounds at pH 7,3.
UOM:  1 * 125 mL
Fournisseur:  MP Biomedicals
Description:   Pokeweed mitogen is extracted from pokeweed roots. This protein has hemagglutinating, leukoagglutinating, and mitogenic properties. It is not blood group specific, but has affinity for N-acetyl-β-D-glucosamine oligomers.
Fournisseur:  MP Biomedicals
Description:   3,3',5,5'-Tetramethylbenzidine (TMB) for ELISA-based applications. Molecular weight: 240,3 g/mol.
Numéro de catalogue: (ICNA08823234)

Fournisseur:  MP Biomedicals
Description:   Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood.
UOM:  1 * 5 g
Fournisseur:  MP Biomedicals
Description:   Digitonin is a mild nonionic detergent. It permeabilizes plasma membranes of eukaryotic cells by complexing with membrane cholesterol and other unconjugated β-hydroxysterols.
Fournisseur:  MP Biomedicals
Description:   Ketoconazole is an antifungal agent; Cytochrome P450 inhibitor and demonstrates anti-psoriatic activity. A liver cytochrome responsible for the metabolism of many drug substrates in humans.
Fournisseur:  MP Biomedicals
Description:   Chloroquine Diphosphate salt is member of quinolone family, Chloroquine is a lysosomotropic agent (accumulate inside the acidic parts of the cell), this accumulation leads to inhibition of lysosomal enzymes that require an acidic pH, and prevents fusion of endosomes and lysosomes.
Standard anti-malarial drug. Substrate for MRP in multidrug resistant cell line and inhibits photoaffinity labeling of MRP by quinoline-based photoactive drug IAAQ (N-[4-[1-hydroxy-2-(dibutylamino)ethyl]quinolin-8-yl]-4-azidosalicylamide).
Numéro de catalogue: (ICNA0290141901)

Fournisseur:  MP Biomedicals
Description:   Soluble in 400 mg plus 4 ml of chloroform - clear, faint yellow to yellow-green.
UOM:  1 * 0,45 kg
Fournisseur:  MP Biomedicals
Description:   Sucrose is a simple carbohydrate, a disaccharide composed of glucose and fructose. It is hydrolyzed to glucose and fructose by dilute acids and by invertase, a yeast enzyme.
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