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ProSci Inc.
Numéro de catalogue:
(PRSI30-291)
Fournisseur:
ProSci Inc.
Description:
The function remains unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI30-275)
Fournisseur:
ProSci Inc.
Description:
GCNT4 is a glycosyltransferase that mediates core 2 O-glycan branching, an important step in mucin-type biosynthesis. It does not have core 4 O-glycan or I-branching enzyme activity.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI30-287)
Fournisseur:
ProSci Inc.
Description:
SERPINE1 acts as 'bait' for tissue plasminogen activator, urokinase, and protein C. Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI45-340)
Fournisseur:
ProSci Inc.
Description:
Anti-BRDT Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI45-336)
Fournisseur:
ProSci Inc.
Description:
Anti-BOLL Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI30-270)
Fournisseur:
ProSci Inc.
Description:
ERGIC3 plays a possible role in transport between endoplasmic reticulum and Golgi.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-509)
Fournisseur:
ProSci Inc.
Description:
Low-Density Lipoprotein (LDL) Receptor is also known as LDLR, FH, FHC, LDLCQ2, and is a mosaic protein of ~840 amino acids (after removal of signal peptide) that mediates the endocytosis of cholesterol-rich LDL. It is a cell-surface receptor that recognizes the apoprotein B100 which is embedded in the phospholipid outer layer of LDL particles. The receptor also recognizes the apoE protein found in chylomicron remnants and VLDL remnants (IDL). It belongs to the Low density lipoprotein receptor gene family. LDL receptor complexes are present in clathrin-coated pits (or buds) on the cell surface, which when bound to LDL-cholesterol via adaptin, are pinched off to form clathrin-coated vesicles inside the cell. This allows LDL-cholesterol to be bound and internalized in a process known as endocytosis and prevents the LDL just diffusing around the membrane surface. This occurs in all nucleated cells (not erythrocytes), but mainly in the liver which removes ~70% of LDL from the circulation. Synthesis of receptors in the cell is regulated by the level of free intracellular cholesterol; if it is in excess for the needs of the cell then the transcription of the receptor gene will be inhibited. LDL receptors are translated by ribosomes on the endoplasmic reticulum and are modified by the Golgi apparatus before travelling in vesicles to the cell surface. LDL is directly involved in the development of atherosclerosis, due to accumulation of LDL-cholesterol in the blood. Atherosclerosis is the process responsible for the majority of cardiovascular diseases.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI28-021)
Fournisseur:
ProSci Inc.
Description:
TRIM26 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI28-033)
Fournisseur:
ProSci Inc.
Description:
DXYS155E is a gene found in the pseudoautosomal region of the distal short arms of the X and Y chromosomes, and appears to be ubiquitously expressed.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI28-026)
Fournisseur:
ProSci Inc.
Description:
COPS2 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP. COPS2 is also innvolved in early stage of neuronal differentiation via its interaction with NIF3L1.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI35-377)
Fournisseur:
ProSci Inc.
Description:
Anti-Streptococcus Rabbit Polyclonal Antibody
UOM:
1 * 1 mL
Numéro de catalogue:
(PRSI28-022)
Fournisseur:
ProSci Inc.
Description:
The CSRP3 gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in CSRP3 are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3819P)
Fournisseur:
ProSci Inc.
Description:
Bik peptide is used for blocking the activity of Bik antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3809P)
Fournisseur:
ProSci Inc.
Description:
TIM-1 peptide is used for blocking activity of TIM-1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI28-750)
Fournisseur:
ProSci Inc.
Description:
NR1I3 mediates the induction of transcription of cytochrome P450 (CYP) genes by phenobarbital (PB) and PB-type inducers. NR1I3 activation induces hepatic expression of detoxification enzymes and transporters and increases liver size. NR1I3 can also regulate both liver homeostasis and tumorigenesis in response to xenobiotic stresses.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI28-765)
Fournisseur:
ProSci Inc.
Description:
RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. RFX is a nuclear protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX.A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS; MIM 209920). At least 4 complementation groups have been identified in B-cell lines established from patients with BLS. The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX.A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS; MIM 209920). At least 4 complementation groups have been identified in B-cell lines established from patients with BLS. The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX, a nuclear protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX (Steimle et al., 1995). RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. Multiple alternatively spliced transcript variants have been found but the full-length natures of only two have been determined.
UOM:
1 * 1 EA
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