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ProSci Inc.
Numéro de catalogue:
(PRSI14-768)
Fournisseur:
ProSci Inc.
Description:
Anti-IFT88 Rabbit Polyclonal Antibody
UOM:
1 * 50 µl
New Product
Numéro de catalogue:
(PRSI14-795)
Fournisseur:
ProSci Inc.
Description:
Anti-MSL2 Rabbit Polyclonal Antibody
UOM:
1 * 50 µl
New Product
Numéro de catalogue:
(PRSI33-849)
Fournisseur:
ProSci Inc.
Description:
S100 belongs to the family of calcium binding proteins. S100 alpha and S100 beta proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the beta-chain (i.e. in S100A and S100B) but not on the alpha-chain of S100 (i.e. in S100A and S100A0). This antibody can be used to localize S100A and S100B in various tissue sections. S100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S100 protein.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI76-853)
Fournisseur:
ProSci Inc.
Description:
The UC10-4F10-11 monoclonal antibody specifically reacts with the mouse Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4), also known as CD152. It is a protein with a structure similar to CD28 regarding the genomic organization, amino acid sequence, and structure. CTLA-4 is expressed on activated T cells and CD25+/CD4+ Treg lymphocytes and binds the members of the B7 family, B7-1 (CD80) and B7-2 (CD86), with higher affinity than CD28. CD28 seems to provide opposing signal to T lymphocytes, while CD152 inhibits the T lymphocytes progression to an activated state and their proliferation, CD28 is a costimulator. The mouse UC10 -4F10-11 monoclonal antibody does not cross-react with the rat leukocytes.
UOM:
1 * 0,1 mg
New Product
Numéro de catalogue:
(PRSI76-846)
Fournisseur:
ProSci Inc.
Description:
The BNI3 monoclonal antibody specifically reacts with human CD152, the Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4). CTLA-4 is expressed on activated CD28+ T cells, and binds the B7 family members B7-1 (CD80) and B7-2 (CD86). The structure of CTLA-4 is similar to the structure of CD28, but the two molecules seem to have opposite roles on the T lymphocytes. CTLA-4 inhibits the progression of T cell activation, while CD28 stimulates it. This result explains the stimulating role that the immobilization of BNI3 plays on the T lymphocytes proliferation induced by CD28.
UOM:
1 * 25 Tests
New Product
Numéro de catalogue:
(PRSI33-457)
Fournisseur:
ProSci Inc.
Description:
Serum Beta-2 Microglobulin (B2M) levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin's lymphoma.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-426)
Fournisseur:
ProSci Inc.
Description:
Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. Antibody to cytokeratin is useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-450)
Fournisseur:
ProSci Inc.
Description:
Recognises a 53 kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-429)
Fournisseur:
ProSci Inc.
Description:
This mAb recognises a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI24-083)
Fournisseur:
ProSci Inc.
Description:
Anti-Fluorescein (FITC) Recombinant Antibody [Clone: 4-4-20 (enhanced)]
UOM:
1 * 0,2 mg
New Product
Numéro de catalogue:
(PRSI24-063)
Fournisseur:
ProSci Inc.
Description:
Anti-His tag Recombinant Antibody [Clone: 3D5]
UOM:
1 * 0,2 mg
New Product
Numéro de catalogue:
(PRSI24-796)
Fournisseur:
ProSci Inc.
Description:
Anti-ADRB2 Recombinant Antibody [Clone: R11/E1]
UOM:
1 * 0,2 mg
New Product
Numéro de catalogue:
(PRSI24-790)
Fournisseur:
ProSci Inc.
Description:
Anti-Ccr9 Recombinant Antibody [Clone: 9B1]
UOM:
1 * 0,2 mg
New Product
Numéro de catalogue:
(PRSI24-775)
Fournisseur:
ProSci Inc.
Description:
Anti-NCR3LG1 Recombinant Antibody [Clone: 17B1.3]
UOM:
1 * 0,2 mg
New Product
Numéro de catalogue:
(PRSI24-763)
Fournisseur:
ProSci Inc.
Description:
Anti-CD8A Recombinant Antibody [Clone: RIV11]
UOM:
1 * 0,2 mg
New Product
Numéro de catalogue:
(PRSI24-757)
Fournisseur:
ProSci Inc.
Description:
Anti-CD53 Recombinant Antibody [Clone: 161-2 (53/2)]
UOM:
1 * 0,2 mg
New Product
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