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ProSci Inc.
Numéro de catalogue:
(PRSI91-573)
Fournisseur:
ProSci Inc.
Description:
Dickkopf-related protein 1(DKK-1), is a member of the dickkopf family. DKK1 secreted proteins with two cysteine-rich domains separated by a linker region. It antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-574)
Fournisseur:
ProSci Inc.
Description:
Tumor necrosis factor receptor superfamily member 1A (Tnfrsf1a) is a member of the tumor necrosis factor receptor superfamily. Tnfrsf1a is one of the major receptors for the tumor necrosis factor-alpha. It can activate the transcription factor NF-κB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the human genetic disorder called tumor necrosis factor associated periodic syndrome (TRAPS) or periodic fever syndrome
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI46-670)
Fournisseur:
ProSci Inc.
Description:
Anti-GRIN2D Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI46-673)
Fournisseur:
ProSci Inc.
Description:
Anti-HRASLS Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI46-648)
Fournisseur:
ProSci Inc.
Description:
Anti-CRHR1 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI46-654)
Fournisseur:
ProSci Inc.
Description:
Anti-EPB41L4B Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI48-207)
Fournisseur:
ProSci Inc.
Description:
Sphingosine kinase (SPHK) phosphorylates sphingosine to form a bioactive lipid mediate, sphingosine 1-phosphate (S1P or SPP). S1P is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival while extracellularly it is a ligand for EDG 1. Expression of SPHK1 and subsequent production of S1P promotes the G1-S transition, protects cells from apoptosis, stimulates migration and angiogenesis, and induces tumor formation in mice.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI46-677)
Fournisseur:
ProSci Inc.
Description:
Anti-ILF2 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI46-652)
Fournisseur:
ProSci Inc.
Description:
Anti-DNMT1 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI46-659)
Fournisseur:
ProSci Inc.
Description:
Anti-FNIP1 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI25-567)
Fournisseur:
ProSci Inc.
Description:
ZNF567 may be involved in transcriptional regulation.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI25-569)
Fournisseur:
ProSci Inc.
Description:
ZNF366 may be involved in transcriptional regulation.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI25-570)
Fournisseur:
ProSci Inc.
Description:
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA9 gene is part of the A cluster on chromosome 7 and the protein is a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis.In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI26-753)
Fournisseur:
ProSci Inc.
Description:
The exact functions of ATXN7L2 remain unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4991P)
Fournisseur:
ProSci Inc.
Description:
ZIP10 peptide is used for blocking the activity of ZIP10 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4999P)
Fournisseur:
ProSci Inc.
Description:
KLRA1 peptide is used for blocking the activity of KLRA1 antibody.
UOM:
1 * 50 µG
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