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ProSci Inc.
Numéro de catalogue:
(PRSI4545P)
Fournisseur:
ProSci Inc.
Description:
IRGM peptide is used for blocking the activity of IRGM antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4549P)
Fournisseur:
ProSci Inc.
Description:
EVER1 peptide is used for blocking the activity of EVER1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4533P)
Fournisseur:
ProSci Inc.
Description:
LGI2 peptide is used for blocking the activity of LGI2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI31-087)
Fournisseur:
ProSci Inc.
Description:
CCR8 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. Its gene is located at the chemokine receptor gene cluster region.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI31-100)
Fournisseur:
ProSci Inc.
Description:
After binding acetylcholine, the ACHR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI31-095)
Fournisseur:
ProSci Inc.
Description:
CHRNB2 is a neuronal nicotinic acetylcholine receptor (nAChR) that belong to ligand-gated ion channels composed of alpha and beta subunits with specific structural, functional and pharmacological properties.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI45-489)
Fournisseur:
ProSci Inc.
Description:
Anti-DOCK1 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI91-489)
Fournisseur:
ProSci Inc.
Description:
The Human Serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. Serpin G1 is a serine protease inhibitor protein. It is the largest member among the serpin class of proteins. Remarkably, Serpin G1 has a 2-domain structure, unlike most family members. The C-terminal serpin domain is similar to other serpins, and this part of Serpin G1 provides the inhibitory activity. The N-terminal domain is not essential for Serpin G1 to inhibit proteinases and has no similarity to other proteins. The main function of Serpin G1 is the inhibition of the complement system to prevent spontaneous activation. Serpin G1 is an acute phase protein and circulates in blood at levels of around 0.25g/L, whose levels rise 2-fold during inflammation. Although named after its complement inhibitory activity, Serpin G1 also inhibits proteinases of the fibrinolytic, clotting, and kinin pathways. Most notably, Serpin G1 play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. It is also the most important physiological inhibitor of fXIIa, chymotrypsin and plasma kallikrein.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-461)
Fournisseur:
ProSci Inc.
Description:
The most prominent members of the interleukin-1 (IL-1) superfamily are IL-1alpha and IL-1beta. They lack a signal peptide and are secreted by an unconventional, endoplasmic reticulum-Golgi-independent mechanism. IL-1alpha was reported to be more widely and constitutively expressed and has intracellular functions, but also acts locally in a membrane-bound form by activating IL-1R1. Additionally, passive release of IL-1alpha upon cell death can trigger a sterile inflammatory response to dying cells. The cleavage of IL-1alpha is not mediated by caspase-1 and is not required for binding to IL-1R1. Recently it has been observed that all activators of the inflammasome NLRP3/NALP3 induce the simultaneous secretion of IL-1alpha and IL-1beta. Although most activators fully rely on the inflammasome for IL-1alpha secretion, some induce the processing and secretion of IL-1alpha in an inflammasome-independent manner.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI25-929)
Fournisseur:
ProSci Inc.
Description:
SLC15A4 is the proton oligopeptide cotransporter. It transports free histidine and certain di- and tripeptides.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI2081P)
Fournisseur:
ProSci Inc.
Description:
ARC peptide is used for blocking the activity of ARC antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI2091P)
Fournisseur:
ProSci Inc.
Description:
CIDE-A peptide is used for blocking the activity of mCIDE-B antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI46-111)
Fournisseur:
ProSci Inc.
Description:
Anti-OSBPL7 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI90-292)
Fournisseur:
ProSci Inc.
Description:
Notch signalling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signalling is also involved in cellular processes through-out adulthood. Signalling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI27-686)
Fournisseur:
ProSci Inc.
Description:
PAX6 is one of many human homologues of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA,This gene encodes paired box gene 6, one of many human homologues of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause aniridia as well as Peter's anomaly, both ocular diseases.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-290)
Fournisseur:
ProSci Inc.
Description:
Interleukin 6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, haematopoiesis, bone metabolism and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It is secreted by multiple cell types as a 22kDa-28kDa phosphorylated and variably glycosylated molecule. IL-6 induces signalling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6R) and a signal transducing subunit (gp130). IL-6 is a key factor for the growth of plasma cells.
UOM:
1 * 1 EA
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