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ProSci Inc.
Numéro de catalogue:
(PRSI31-120)
Fournisseur:
ProSci Inc.
Description:
The 'SNARE hypothesis' is a model explaining the process of docking and fusion of vesicles to their target membranes. According to this model, membrane proteins from the vesicle (v-SNAREs) and proteins from the target membrane (t-SNAREs) govern the specificity of vesicle targeting and docking through mutual recognition. Once the 2 classes of SNAREs bind to each other, they form a complex that recruits the general elements of the fusion apparatus, namely NSF (N-ethylmaleimide-sensitive factor) and SNAPs (soluble NSF-attachment proteins), to the site of membrane fusion, thereby forming the 20S fusion complex. Alpha- and gamma-SNAP are found in a wide range of tissues and act synergistically in intra-Golgi transport. The sequence of the predicted 295-amino acid human protein encoded by NAPA shares 37%, 60%, and 67% identity with the sequences of yeast, Drosophila, and squid alpha-SNAP, respectively.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI31-122)
Fournisseur:
ProSci Inc.
Description:
MCH may act as a neurotransmitter or neuromodulator in a broad array of neuronal functions directed toward the regulation of goal-directed behavior, such as food intake, and general arousal. May also have a role in spermatocyte differentiation.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI90-467)
Fournisseur:
ProSci Inc.
Description:
Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells, and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils, and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important hemeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI46-911)
Fournisseur:
ProSci Inc.
Description:
Anti-TRAF3IP1 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI46-927)
Fournisseur:
ProSci Inc.
Description:
Anti-HAX1 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI26-189)
Fournisseur:
ProSci Inc.
Description:
ABI3BP contains 2 fibronectin type-III domains. The loss of ABI3BP expression could play a functional role in thyroid tumorigenesis. It also presumably represents a trigger gene for evoking cellular senescence, which has also been suggested to be involved in the prevention of tumorigenesis.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI26-183)
Fournisseur:
ProSci Inc.
Description:
P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu (2+) or Cd (2+). Another subfamily transports non-heavy metal ions, such as H (+), Na (+), K (+), or Ca (+). A third subfamily transports amphipaths, such as phosphatidylserine.P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu (2+) or Cd (2+). Another subfamily transports non-heavy metal ions, such as H (+), Na (+), K (+), or Ca (+). A third subfamily transports amphipaths, such as phosphatidylserine.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6705P)
Fournisseur:
ProSci Inc.
Description:
IRF2BP2 peptide is used for blocking the activity of IRF2BP2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6737P)
Fournisseur:
ProSci Inc.
Description:
ANGPT2 peptide is used for blocking the activity of ANGPT2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI46-269)
Fournisseur:
ProSci Inc.
Description:
Anti-RASAL Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI46-906)
Fournisseur:
ProSci Inc.
Description:
Anti-TFEB Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI51-266)
Fournisseur:
ProSci Inc.
Description:
Anti-C5AR1 Rabbit Polyclonal Antibody
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI51-257)
Fournisseur:
ProSci Inc.
Description:
Anti-NR1D2 Rabbit Polyclonal Antibody
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI28-768)
Fournisseur:
ProSci Inc.
Description:
BACH1 is a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. Some exons of this gene overlap with some exons from the C21orf41 gene, which is transcribed in an opposite orientation to this gene but does not seem to encode a protein.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI25-893)
Fournisseur:
ProSci Inc.
Description:
SLC10A7 belongs to the sodium: bile acid symporter family. It is a multi-pass membrane protein. The function of SLC10A7 remains unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI26-771)
Fournisseur:
ProSci Inc.
Description:
Members of the F-box protein family, such as FBXO36, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.Members of the F-box protein family, such as FBXO36, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
UOM:
1 * 50 µG
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