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ProSci Inc.
Numéro de catalogue:
(PRSI14-662)
Fournisseur:
ProSci Inc.
Description:
Anti-STYXL1 Rabbit Polyclonal Antibody
UOM:
1 * 50 µl
New Product
Numéro de catalogue:
(PRSI33-874)
Fournisseur:
ProSci Inc.
Description:
This antibody recognises a 67 kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. antibody to CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. CD5 antibody detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. CD5 antibody is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, antibody to CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). CD5 antibody does not react with granulocytes or monocytes.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI60-098)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI60-095)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI33-427)
Fournisseur:
ProSci Inc.
Description:
It recognises an intermediate filament protein (IFP) of 55 kDa, which is identified as cytokeratin 7. This mAb is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. This mAb is highly useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-461)
Fournisseur:
ProSci Inc.
Description:
Recognises a 12-14 kDa doublet of Calgranulin A/B (also known as S100A8/A9 or MRP-8/14); expressed by granulocytes, monocytes and by tissue macrophages. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. Altered expression of this protein is associated with the disease cystic fibrosis. This mAb reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia and has been shown as an important marker for identifying macrophages in tissue sections.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-440)
Fournisseur:
ProSci Inc.
Description:
Recognises a sialoglycoprotein of 27 to 32 kDa, identified as CD99, or MIC2 gene product, or E2 antigen. MIC2 gene is located in the pseudo-autosomal region of the human X and Y chromosome. MIC2 gene encodes two distinct proteins, which are produced by alternative splicing of the CD99 gene transcript and are identified as bands of 30 and 32 kDa (p30/32). Although its function is not fully understood, CD99 is implicated in various cellular processes including homotypic aggregation of T cells, upregulation of T cell receptor and MHS molecules, apoptosis of immature thymocytes and leukocyte diapedesis. CD99 is expressed on the cell membrane of some lymphocytes, cortical thymocytes, and granulosa cells of the ovary. Most pancreatic islet cells, Sertoli cells of the testis, and some endothelial cells express this antigen. Mature granulocytes express very little or no CD99. It is strongly expressed on Ewing s sarcoma cells and primitive peripheral neuroectodermal tumors.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-443)
Fournisseur:
ProSci Inc.
Description:
This mAb recognises full-length MUC1/Mucin-1/Epithelial Marker Antigen/EMA in a glycosylation-independent manner and can bind to the fully glycosylated protein. The dominant epitope of this mAb is APDTR in the VNTR region. It reacts with the core peptide of the MUC1 protein, which is a member of a family of mucin glycoproteins that are characterised by high carbohydrate content, O-linked oligosaccharides, high molecular weight (>200 kDa) and an amino acid composition rich in serine, threonine, proline and glycine. The core protein contains a domain of 20 amino-acid tandem repeats that functions as multiple epitopes for the mAb. Incomplete glycosylation of some tumor-associated mucins may lead to variable unmasking of the multiple peptide epitopes leading to the observed differences in staining intensity between normal and malignant tissues. This mAb reacts with both normal and malignant epithelia of various tissues including breast and colon.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-445)
Fournisseur:
ProSci Inc.
Description:
It recognises a protein of HMW, identified as mucin 3 glycoprotein (MUC3). This mAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC2. The Mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) encoded by 60 base pairs (Mucin 1), 69 base pairs (Mucin 2) and 51 base pairs (Mucin 3). The number of repeats is highly polymorphic and varies among different alleles. Mucin 1 proteins are expressed as type I membrane proteins in addition to secreted forms. Mucin 1 is aberrantly expressed in epithelial tumors including breast carcinomas. Mucin 2 coats the epithelia of the intestines and airways and is associated with colonic tumors. Mucin 3 is a major component of various mucus gels and is broadly expressed in normal and tumor cells.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-468)
Fournisseur:
ProSci Inc.
Description:
This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. TGFa is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI24-082)
Fournisseur:
ProSci Inc.
Description:
Anti-Fluorescein (FITC) Recombinant Antibody [Clone: 4-4-20 (enhanced)]
UOM:
1 * 0,2 mg
New Product
Numéro de catalogue:
(PRSI24-055)
Fournisseur:
ProSci Inc.
Description:
Anti-His tag Recombinant Antibody [Clone: 3D5]
UOM:
1 * 0,2 mg
New Product
Numéro de catalogue:
(PRSI24-754)
Fournisseur:
ProSci Inc.
Description:
Anti-CD37 Recombinant Antibody [Clone: IPO-24 (ZC37-24)]
UOM:
1 * 0,2 mg
New Product
Numéro de catalogue:
(PRSI24-770)
Fournisseur:
ProSci Inc.
Description:
Anti-CD4 Recombinant Antibody [Clone: EDU-2 (B486)]
UOM:
1 * 0,2 mg
New Product
Numéro de catalogue:
(PRSI24-760)
Fournisseur:
ProSci Inc.
Description:
Anti-CD59 Recombinant Antibody [Clone: 193-27]
UOM:
1 * 0,2 mg
New Product
Numéro de catalogue:
(PRSI24-774)
Fournisseur:
ProSci Inc.
Description:
Anti-Cd79b Recombinant Antibody [Clone: HM79-16]
UOM:
1 * 0,2 mg
New Product
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