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Numéro de catalogue:
(PRSI79-907)
Fournisseur:
ProSci Inc.
Description:
The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-902)
Fournisseur:
ProSci Inc.
Description:
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI25-411)
Fournisseur:
ProSci Inc.
Description:
MAZ may function as a transcription factor with dual roles in transcription initiation and termination.It binds to two sites, ME1a1 and ME1a2, within the c-myc promoter having greater affinity for the former. It also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI25-409)
Fournisseur:
ProSci Inc.
Description:
GTF2E2 belongs to the TFIIE beta subunit family.It recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6385P)
Fournisseur:
ProSci Inc.
Description:
GEMC1 peptide is used for blocking the activity of GEMC1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6399P)
Fournisseur:
ProSci Inc.
Description:
CCDC141 peptide is used for blocking the activity of CCDC141 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI25-412)
Fournisseur:
ProSci Inc.
Description:
The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage.MNDA may act as a transcriptional activator/repressor in the myeloid lineage. It plays a role in the granulocyte/monocyte cell-specific response to interferon. MNDA stimulates the DNA binding of the transcriptional repressor protein YY1.The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI45-034)
Fournisseur:
ProSci Inc.
Description:
Anti-CDX2 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI91-026)
Fournisseur:
ProSci Inc.
Description:
Interleukin-8 (IL-8) belongs to the neutrophil-specific CXC family of chemokines. It is one of the initial cytokines released from a variety of cell types, including T cells, endothelial cells and fibroblasts, in response to an inflammatory stimulus and acts by recruiting neutrophils, T-cells and basophils to the site of inflammation. Elevated Interleukin-8 levels are associated with the onset of a variety of disease states.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-031)
Fournisseur:
ProSci Inc.
Description:
Mouse Interleukin-1 (IL-1) designates two proteins, IL-1 alpha and IL-1 beta , which are the products of distinct genes, but recognize the same cell surface receptors. IL-1 alpha and IL-1 beta are structurally related polypeptides that show approximately 25% homology at the amino acid level. Both proteins are produced by a wide variety of cells in response to stimuli such as those produced by inflammatory agents, infections, or microbial endotoxins. The proteins are synthesized as 31 kDa precursors that are subsequently cleaved into proteins with molecular weights of approximately 17.5 kDa.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-021)
Fournisseur:
ProSci Inc.
Description:
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Today, IL-17 represents a family of structurally related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-286)
Fournisseur:
ProSci Inc.
Description:
As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI30-556)
Fournisseur:
ProSci Inc.
Description:
LRRC8 is a multi-pass membrane protein. It contains 13 LRR (leucine-rich) repeats. LRRC8 involved in B cell development belongs to a novel family of leucine-rich repeat proteins
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI30-552)
Fournisseur:
ProSci Inc.
Description:
TREML2 is a single-pass type I membrane protein, and it contains 1 Ig-like V-type (immunoglobulin-like) domain. TREML2 is a cell surface receptor that may play a role in the innate and adaptive immune response. TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties (Allcock et al., 2003 [PubMed 12645956]).
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI31-276)
Fournisseur:
ProSci Inc.
Description:
ZNF566 may be involved in transcriptional regulation.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI42-544)
Fournisseur:
ProSci Inc.
Description:
Anti-MECOM Goat Polyclonal Antibody
UOM:
1 * 1 EA
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