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ProSci Inc.
Numéro de catalogue:
(PRSI35-675)
Fournisseur:
ProSci Inc.
Description:
Anti-Verotoxins Mouse Monoclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI91-565)
Fournisseur:
ProSci Inc.
Description:
Secretagogin (SCGN) is a secreted calcium-binding protein that is found in the cytoplasm; a small proportion is associated with secretory granules and membrane fractions. SCGN contains six EF-hand domains, related to calbindin D-28K and calretinin. SCGN is thought to be involved in KCL-stimulated calcium flux and cell proliferation SCGN can be detected in human serum after ischemic neuronal damage. SCGN may function to negatively control growth and differentiation rates and, thus, indirectly inhibit cell replication.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI45-605)
Fournisseur:
ProSci Inc.
Description:
Anti-FOXC2 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI45-602)
Fournisseur:
ProSci Inc.
Description:
Anti-FOXB1 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI45-603)
Fournisseur:
ProSci Inc.
Description:
Anti-FOXC1 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI91-573)
Fournisseur:
ProSci Inc.
Description:
Dickkopf-related protein 1(DKK-1), is a member of the dickkopf family. DKK1 secreted proteins with two cysteine-rich domains separated by a linker region. It antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-574)
Fournisseur:
ProSci Inc.
Description:
Tumor necrosis factor receptor superfamily member 1A (Tnfrsf1a) is a member of the tumor necrosis factor receptor superfamily. Tnfrsf1a is one of the major receptors for the tumor necrosis factor-alpha. It can activate the transcription factor NF-κB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the human genetic disorder called tumor necrosis factor associated periodic syndrome (TRAPS) or periodic fever syndrome
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI51-562)
Fournisseur:
ProSci Inc.
Description:
Anti-CD79a Mouse Monoclonal Antibody
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI71-375)
Fournisseur:
ProSci Inc.
Description:
Anti-GPR34 Rabbit Polyclonal Antibody
UOM:
1 * 50 µl
Numéro de catalogue:
(PRSI79-109)
Fournisseur:
ProSci Inc.
Description:
NF-κ-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-κ-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-κ-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-κ-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-κ-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-κ-B complex which translocates to the nucleus. NF-κ-B heterodimeric p65-p50 and p65-c-Rel complexes are transcriptional activators. The NF-κ-B p65-p65 complex appears to be involved in invasin-mediated activation of IL-8 expression. The inhibitory effect of I-kappa-B upon NF-κ-B the cytoplasm is exerted primarily through the interaction with p65. p65 shows a weak DNA-binding site which could contribute directly to DNA binding in the NF-κ-B complex.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-117)
Fournisseur:
ProSci Inc.
Description:
Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI71-392)
Fournisseur:
ProSci Inc.
Description:
Anti-GALNT7 Rabbit Polyclonal Antibody
UOM:
1 * 50 µl
Numéro de catalogue:
(PRSI42-345)
Fournisseur:
ProSci Inc.
Description:
Anti-BTBD7 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI42-342)
Fournisseur:
ProSci Inc.
Description:
Anti-HTR1A Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSIXP-5147)
Fournisseur:
ProSci Inc.
Description:
Anti-CXCL1 Rabbit Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSIXP-5152)
Fournisseur:
ProSci Inc.
Description:
Anti-CCL1 Rabbit Polyclonal Antibody
UOM:
1 * 1 EA
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