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Numéro de catalogue:
(PRSI25-446)
Fournisseur:
ProSci Inc.
Description:
NAB2 is a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize withThis gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI25-428)
Fournisseur:
ProSci Inc.
Description:
ZNF157 belongs to the krueppel C2H2-type zinc-finger protein family. It contains 12 C2H2-type zinc fingers and 1 KRAB domain. ZNF157 may be involved in transcriptional regulation. This gene product is a likely zinc finger family transcription factor. It contains KRAB-A and KRAB-B domains that act as transcriptional repressors in related proteins, and multiple zinc finger DNA binding motifs and finger linking regions characteristic of the Kruppel family. This gene is part of a gene cluster on chromosome Xp11.23.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI25-425)
Fournisseur:
ProSci Inc.
Description:
ZFY is a zinc finger-containing protein that may function as a transcription factor. ZFY was once a candidate gene for the testis-determining factor (TDF) and was erroneously referred to as TDF.This gene encodes a zinc finger-containing protein that may function as a transcription factor. This gene was once a candidate gene for the testis-determining factor (TDF) and was erroneously referred to as TDF. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI26-268)
Fournisseur:
ProSci Inc.
Description:
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6843P)
Fournisseur:
ProSci Inc.
Description:
THBS4 peptide is used for blocking the activity of THBS4 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6833P)
Fournisseur:
ProSci Inc.
Description:
CLEC7A peptide is used for blocking the activity of CLEC7A antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI29-927)
Fournisseur:
ProSci Inc.
Description:
SLC43A3 belongs to the SLC43A transporter family and is a putative transporter.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI27-637)
Fournisseur:
ProSci Inc.
Description:
MKX contains 1 homeobox DNA-binding domain and belongs to the TALE/IRO homeobox family. It may act as a morphogenetic regulator of cell adhesion.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI45-379)
Fournisseur:
ProSci Inc.
Description:
Anti-CCL3L1 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI45-383)
Fournisseur:
ProSci Inc.
Description:
Anti-FCGR2B Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI27-647)
Fournisseur:
ProSci Inc.
Description:
HS1 which is hematopoietic lineage cell-specific protein 1, is a substrate of protein tyrosine kinases in lymphocytes, it binds to F-actin, and promotes Arp2/3 complex-mediated actin polymerization. However, the mechanism for the interaction between HS1 and F-actin has not yet been fully characterized. HS1 contains 3.5 tandem repeats, a coiled-coil region, and an SH3 domain at the C terminus. Unlike cortactin, which is closely related to HS1 and requires absolutely the repeat domain for F-actin binding, an HS1 mutant with deletion of the repeat domain maintains a significant F-actin binding activity. Deletion of the coiled-coil region abolished the ability of HS1 to bind to actin filaments and to activate the Arp2/3 complex for actin nucleation and actin branching.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI27-644)
Fournisseur:
ProSci Inc.
Description:
TFCP2L1 is a transcriptional suppressor. TFCP2L1 may suppress UBP1-mediated transcriptional activation. It modulates the placental expression of CYP11A1.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3409)
Fournisseur:
ProSci Inc.
Description:
XAF-1 Antibody: XAF-1 binds to XIAP, an inhibitor of caspases-3, -7, and -9, and triggers its relocation from the cytosol to the nucleus. Overexpression of XAF-1 results in the neutralization of XIAP's ability to inhibit cell death. XAF-1 is normally expressed in all adult and fetal tissues but was found to be present in very low levels in a variety of cancer cell lines. In contrast, XIAP levels have been shown to be high in a majority of cell lines. Low XAF-1 and high basal expression of XIAP may therefore play a critical role in maintaining survival of cancer cell lines. Both IFN-alpha2 and IFN-beta can induce XAF-1 mRNA in all cells examined but induction of XAF-1 protein (as observed by immunoblot analysis) was seen only in cell lines sensitive to the apoptotic effects of IFNs.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI27-496)
Fournisseur:
ProSci Inc.
Description:
PBX3 is a transcriptional activator that binds the sequence 5'-ATCAATCAA-3'.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI28-078)
Fournisseur:
ProSci Inc.
Description:
NSEP1 is a cell cycle stage-specific transcription factor important for cell proliferation. NSEP1 encodes a protein that correlates with P-glycoprotein expression in human breast carcinoma.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3871)
Fournisseur:
ProSci Inc.
Description:
BAG-1 Antibody: Bcl-2-associated athanogene 1 (BAG-1) was first identified as an anti-apoptotic bcl-2-binding protein. Later it was found to bind the molecular chaperones Hsp70 and Hsc70 through its carboxy-terminal sequence (termed the Bag domain), resulting in the inhibition of the refolding activity of these chaperones. It is thought that by binding and inhibiting these molecular chaperones, BAG-1is able to modulate the expression level of proteins requiring chaperones to fold correctly. One such group of proteins that are affected is glucocorticoid receptors. Other reports have suggested that the level of BAG-1 expression correlates with the aggressiveness of various cancers. Multiple isoforms of BAG-1 are known to exist.
UOM:
1 * 1 EA
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