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ProSci Inc.
Numéro de catalogue:
(PRSI79-802)
Fournisseur:
ProSci Inc.
Description:
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI28-596)
Fournisseur:
ProSci Inc.
Description:
Stat1 is a member of the STAT family. It can form homodimers to modulate the transcriptional repression of PPARgamma2 in adipocytes
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI28-597)
Fournisseur:
ProSci Inc.
Description:
TFAM a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this protein is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns Sayre syndrome was produced when expression of the gene was eliminated by targeted disruption in heart and muscle cells.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI29-179)
Fournisseur:
ProSci Inc.
Description:
ZSCAN2 contains several copies of zinc finger motif, which is commonly found in transcriptional regulatory proteins. Studies in mice show that ZSCAN2 is expressed during embryonic development, and specifically in the testis in adult mice, suggesting that it may play a role in regulating genes in germ cells.The protein encoded by this gene contains several copies of zinc finger motif, which is commonly found in transcriptional regulatory proteins. Studies in mice show that this gene is expressed during embryonic development, and specifically in the testis in adult mice, suggesting that it may play a role in regulating genes in germ cells. Alternative splicing of this gene results in several transcript variants encoding different isoforms.The protein encoded by this gene contains several copies of zinc finger motif, which is commonly found in transcriptional regulatory proteins. Studies in mice show that this gene is expressed during embryonic development, and specifically in the testis in adult mice, suggesting that it may play a role in regulating genes in germ cells. Alternative splicing of this gene results in several transcript variants encoding different isoforms.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6931)
Fournisseur:
ProSci Inc.
Description:
COH1 Antibody: COH1 (Cohen syndrome protein 1), also known as VPS13B (vacuolar protein sorting-associated protein 13B) or CHS1, belongs to the VPS13 family and may function in vesicle-mediated transport and sorting of proteins within the cell. COH1 is widely expressed and multiple alternatively spliced transcript variants have been observed. Mutations in this gene have been associated with Cohen syndrome. COH1 is a Golgi-localized peripheral membrane protein and plays a critical role in Golgi (re)assembly.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI6909)
Fournisseur:
ProSci Inc.
Description:
BMP15 Antibody: BMP15, or GDF9B is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily that are involved in embryonic development and adult tissue homeostasis. BMP15 is expressed exclusively in the oocyte. It is an oocyte-specific growth/differentiation factor that may be involved in oocyte maturation and follicular development. Defects in BMP15 are the cause of ovarian dysgenesis type 2. BMP15 could be used as an oogenesis marker to track human amniotic fluid stem cells differentiation into the oocyte-like cells.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI7291P)
Fournisseur:
ProSci Inc.
Description:
15 amino acids near the carboxy terminus of human TMEM135.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7285P)
Fournisseur:
ProSci Inc.
Description:
18 amino acids near the amino terminus of human MTERFD3.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7305P)
Fournisseur:
ProSci Inc.
Description:
16 amino acids near the amino terminus of human TIAF.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSIXP-5284)
Fournisseur:
ProSci Inc.
Description:
Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide stimulated macrophages, and causes tumor necrosis when injected into tumour bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSIXP-5286BT)
Fournisseur:
ProSci Inc.
Description:
Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide stimulated macrophages, and causes tumor necrosis when injected into tumour bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-546)
Fournisseur:
ProSci Inc.
Description:
Ephrin type-A receptor 4(EPHA4) belongs to the protein kinase superfamily and Ephrin receptor subfamily. EPHA4 contains 1 Eph LBD domain, 2 fibronectin type-III domains, 1 protein kinase domain and 1 SAM domain. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI28-990)
Fournisseur:
ProSci Inc.
Description:
MAFF is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. MAFF can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. MAFF may also be involved in the cellular stress response.The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Two transcript variants encoding the same protein have been found for this gene.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI28-998)
Fournisseur:
ProSci Inc.
Description:
CNOT7 binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs.The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI29-004)
Fournisseur:
ProSci Inc.
Description:
CBX6 is involved in maintaining the transcriptionally repressive state of genes. It modifies chromatin, rendering it heritably changed in its expressibility.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI42-911)
Fournisseur:
ProSci Inc.
Description:
Anti-HP Goat Polyclonal Antibody
UOM:
1 * 1 EA
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