Supplier >
ProSci Inc.
Imprimer
Votre recherche pour:
38 900 les résultats ont été trouvés
ProSci Inc.
Numéro de catalogue:
(PRSI33-311)
Fournisseur:
ProSci Inc.
Description:
This mAb recognises a 21 kDa protein, identified as the p21WAF1 tumor suppressor protein. This mAb is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdk s and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-341)
Fournisseur:
ProSci Inc.
Description:
This mAb recognises granulocyte-colony stimulating factor (G-CSF) in the cytoplasm of mature granulocytes. It shows no reactivity with any other cell types. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. It reacts with early precursor and mature forms of myeloid cells. It is useful for the detection of myeloid leukemias and granulocytic sarcomas. It can be used as a marker of granulocytes in normal tissues or inflammatory processes.G-CSF is a pleiotropic cytokine that influences differentiation, proliferation and activation of the neutrophilic granulocyte lineage. The human G-CSF cDNA encodes a 207 amino acid precursor containing a 29 amino acid signal peptide that is proteolytically cleaved to form a 178 amino acid residue mature protein. Two G-CSFs, which are identical except for a three amino acid deletion in the amino-terminus of one form of the protein have been isolated from human cells. Murine and human G-CSF s share 73% sequence identity at the amino acid level.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI10-723)
Fournisseur:
ProSci Inc.
Description:
Anti-REGN-1033 Recombinant Antibody
UOM:
1 * 0,1 mg
New Product
Numéro de catalogue:
(PRSI10-741)
Fournisseur:
ProSci Inc.
Description:
Anti-REGN-2176 Recombinant Antibody
UOM:
1 * 0,1 mg
New Product
Numéro de catalogue:
(PRSI62-986)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:10~50.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI56-742)
Fournisseur:
ProSci Inc.
Description:
ZNF429 may be involved in transcriptional regulation.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI56-762)
Fournisseur:
ProSci Inc.
Description:
This gene encodes a protein which is part of the ubiquinol-cytochrome c oxidoreductase complex which contains ten nuclear-encoded and one mitochondrial-encoded subunits. The encoded protein binds ubiquinone and participates in the transfer of electrons when ubiquinone is bound. Mutations in this gene are associated with mitochondrial complex III deficiency. A pseudogene has been described on the X chromosome.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI61-689)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI56-748)
Fournisseur:
ProSci Inc.
Description:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq].
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI33-933)
Fournisseur:
ProSci Inc.
Description:
The small ubiquitin-related modifier (SUMO) proteins, which include SUMO1, 2 and 3, belong to the ubiquitin-like protein family. SUMO proteins are synthesised as precursors that undergo processing before conjugation to target proteins. Sumoylation targets for a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. SUMO2/3 contribute to a greater percentage of protein modification than does SUMO1 and they can form polymeric chains. In addition, SUMO3 regulates beta-Amyloid generation and may be critical in the onset or progression of Alzheimer’s disease.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-947)
Fournisseur:
ProSci Inc.
Description:
Moesin (for membrane-organizing extension spike protein) is a member of the ERM protein family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. [Wiki].
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-910)
Fournisseur:
ProSci Inc.
Description:
Estrogen receptor (ER) is an important regulator of growth and differentiation in the mammary gland. ER presence in breast tumors indicates an increased likelihood of response to anti-estrogen therapy.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-934)
Fournisseur:
ProSci Inc.
Description:
Mucosa associated lymphoid tissue lymphoma translocation gene 1 is found in extranodal low-grade B cell lymphomas. It encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of the MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-903)
Fournisseur:
ProSci Inc.
Description:
The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, 2 and 3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesised as precursor proteins that undergo processing before conjugation to target proteins. Sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1, 2 and 3 proteins localize to the nuclear membrane, nuclear bodies and cytoplasm, respectively. SUMO-2 and 3 contribute to a greater percentage of protein modification than does SUMO-1 and unlike SUMO-1, they can form polymeric chains.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI59-368)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI59-359)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000.
UOM:
1 * 400 µl
New Product
Appel de prix
Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'
 est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'
est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
Ces articles ne peuvent être ajoutés au Panier. Veuillez contacter votre service client ou envoyer un e-mail à vwr.be@vwr.com
Une documentation supplémentaire peut être nécessaire pour l'achat de cet article. Un représentant de VWR vous contactera si nécessaire.
Ce produit a été bloqué par votre organisation. Contacter votre service d'achat pour plus d'informations.
Le produit original n'est plus disponible. Le remplacement représenté est disponible
Les produits marqués de ce symbole ne seront bientôt plus disponibles - vente jusqu'à épuisement de stock. Des alternatives peuvent être disponibles en recherchant le code article VWR indiqué ci-dessus. Si vous avez besoin d'une assistance supplémentaire, veuillez contacter notre Service Clientèle au 016 385 011.
|
|||||||||
Vue liste
