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ProSci Inc.
Numéro de catalogue:
(PRSI76-853)
Fournisseur:
ProSci Inc.
Description:
The UC10-4F10-11 monoclonal antibody specifically reacts with the mouse Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4), also known as CD152. It is a protein with a structure similar to CD28 regarding the genomic organization, amino acid sequence, and structure. CTLA-4 is expressed on activated T cells and CD25+/CD4+ Treg lymphocytes and binds the members of the B7 family, B7-1 (CD80) and B7-2 (CD86), with higher affinity than CD28. CD28 seems to provide opposing signal to T lymphocytes, while CD152 inhibits the T lymphocytes progression to an activated state and their proliferation, CD28 is a costimulator. The mouse UC10 -4F10-11 monoclonal antibody does not cross-react with the rat leukocytes.
UOM:
1 * 0,1 mg
New Product
Numéro de catalogue:
(PRSI76-846)
Fournisseur:
ProSci Inc.
Description:
The BNI3 monoclonal antibody specifically reacts with human CD152, the Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4). CTLA-4 is expressed on activated CD28+ T cells, and binds the B7 family members B7-1 (CD80) and B7-2 (CD86). The structure of CTLA-4 is similar to the structure of CD28, but the two molecules seem to have opposite roles on the T lymphocytes. CTLA-4 inhibits the progression of T cell activation, while CD28 stimulates it. This result explains the stimulating role that the immobilization of BNI3 plays on the T lymphocytes proliferation induced by CD28.
UOM:
1 * 25 Tests
New Product
Numéro de catalogue:
(PRSI60-106)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI10-890)
Fournisseur:
ProSci Inc.
Description:
Anti-JNJ-63723283 Recombinant Antibody
UOM:
1 * 0,1 mg
New Product
Numéro de catalogue:
(PRSI10-869)
Fournisseur:
ProSci Inc.
Description:
Anti-BMS-986016 Recombinant Antibody
UOM:
1 * 0,1 mg
New Product
Numéro de catalogue:
(PRSI10-916)
Fournisseur:
ProSci Inc.
Description:
Anti-BAY 1213790 Recombinant Antibody
UOM:
1 * 0,1 mg
New Product
Numéro de catalogue:
(PRSI63-533)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI58-581)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000. For FACS starting dilution is: 1:10~50.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI63-541)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI61-233)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:2000.
UOM:
1 * 200 µl
New Product
Numéro de catalogue:
(PRSI61-227)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI61-246)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000.
UOM:
1 * 200 µl
New Product
Numéro de catalogue:
(PRSI33-879)
Fournisseur:
ProSci Inc.
Description:
VEGFR1 is high affinity receptors for vascular endothelial growth factors (VEGFs). On the basis of structural similarity to VEGFR1 and 2, it has been speculated that Flt-4 might represent a third receptor for either VEGF or a VEGF-related ligand.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-885)
Fournisseur:
ProSci Inc.
Description:
AMPD3 is a member of the AMP deaminase gene family. It is a highly regulated enzyme that catalyses the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. This gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in the gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. [RefSeq].
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-849)
Fournisseur:
ProSci Inc.
Description:
S100 belongs to the family of calcium binding proteins. S100 alpha and S100 beta proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the beta-chain (i.e. in S100A and S100B) but not on the alpha-chain of S100 (i.e. in S100A and S100A0). This antibody can be used to localize S100A and S100B in various tissue sections. S100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S100 protein.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-876)
Fournisseur:
ProSci Inc.
Description:
This antibody reacts with a protein of 22 kDa, identified as beta subunit of HCG. It does not cross react with the alpha subunit. HCG is a glycoprotein which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). HCG-beta antibody detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate antibody positivity in 90% and 60% of cases respectively; 20% of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior.
UOM:
1 * 1 EA
New Product
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