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ProSci Inc.
Numéro de catalogue:
(PRSI2097)
Fournisseur:
ProSci Inc.
Description:
CCR8 Antibody: CCR8 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human and murine CCR8 were cloned and designated TER1, CKR-L1, and ChemR1. The encoded seven transmembrane protein was identified as the receptor for human CC chemokine I-309 and renamed CCR8. Recently, CCR8 was found to serve as a coreceptor for diverse T-cell tropic, dual-tropic and macrophage-tropic HIV-1 strains. CCR8 mediates CC chemokine I-309 induced monocyte chemoattraction and HIV-1 envelope fusion and virus infection, which can be prevented by the CCR8 ligand I-309. CCR8 is expressed in spleen, thymus and T lymphoblastic cell lines.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI25-431)
Fournisseur:
ProSci Inc.
Description:
TEAD2 contains 1 TEA DNA-binding domain. TEAD2 is a putative transcription factor that binds to the SPH and GT-IIC enhansons (5'-GTGGAATGT-3'). It may be involved in the gene regulation of neural development.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI25-426)
Fournisseur:
ProSci Inc.
Description:
The exact function of ZNF124 remains unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI38-128)
Fournisseur:
ProSci Inc.
Description:
The MDC gene is one of several Cys-Cys (CC) cytokine genes which are clustered on the q arm of chromosome 16.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI45-736)
Fournisseur:
ProSci Inc.
Description:
Anti-HMG20A Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI91-702)
Fournisseur:
ProSci Inc.
Description:
Inositol Polyphosphate 1-Phosphatase (INPP1) is a member of the inositol monophosphatase family. INPP1 is widely expressed in tissues, with highest expression levels observed in the pancreas and kidney. INPP1 is inhibited by Li+. Removing the phosphate group at position 1 of the inositol ring from the polyphosphates inositol 1,4-bisphosphate and inositol 1,3,4-trisphophosphate. INPP1 is involved in signal transduction and phosphatidylinositol signaling pathway.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI38-113)
Fournisseur:
ProSci Inc.
Description:
Anti-CD22 Rabbit Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI29-243)
Fournisseur:
ProSci Inc.
Description:
GTPBP9 belongs to the GTP1/OBG family and the function remains unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI29-240)
Fournisseur:
ProSci Inc.
Description:
SNRP70 contains 1 RRM (RNA recognition motif) domain and mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI29-809)
Fournisseur:
ProSci Inc.
Description:
Rgs2 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. It may play a role in leukemogenesis.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI42-487)
Fournisseur:
ProSci Inc.
Description:
Anti-EXT2 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI42-482)
Fournisseur:
ProSci Inc.
Description:
Anti-UTF1 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-530)
Fournisseur:
ProSci Inc.
Description:
p53 is a nuclear protein which plays an essential role in the regulation of cell cycle specifically in the transition from G0 to G1. It is found in very low levels in normal cells however in a variety of transformed cell lines in high amounts and believed to contribute to transformation and malignancy. The open reading frame of p53 is 393 amino acids long, with the central region (consisting of amino acids from about 100 to 300) containing the DNA-binding domain. This proteolysis-resistant core is flanked by a C-terminal end mediating oligomerization and an N-terminal end containing a strong transcription activation signal. p53 binds as a tetramer to a PBS (p53-Binding Site) and activates the expression of downstream genes that inhibit growth and/or invasion. p53 binds as a tetramer to a p53-binding site (PBS) and to activate the expression of adjacent genes that inhibit growth and/or invasion. Deletion of one or both p53 alleles reduces the expression of tetramers, resulting in decreased expression of the growth inhibitory genes
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI71-096)
Fournisseur:
ProSci Inc.
Description:
Anti-SLITRK6 Rabbit Polyclonal Antibody
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI79-528)
Fournisseur:
ProSci Inc.
Description:
This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSIPM-6585-HRP)
Fournisseur:
ProSci Inc.
Description:
HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix. The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein. The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines.
UOM:
1 * 1 EA
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