STEMCELL Technologies
Numéro de catalogue:
(STMC100-1323)
Fournisseur:
STEMCELL Technologies
Description:
Mediate calcium phosphate clearance and prevent ectopic calcification with fetuin A, a plasma glycoprotein that forms soluble complexes with calcium and phosphate (Heiss <i>et al.</i>; Price and Lin). Belonging to the cystatin superfamily of cysteine protease inhibitors (Brown and Dziegielewska), fetuin A has also been shown to play a role in lipid transport, acting as a carrier (Kumbla <i>et al.</i>). In cell-based assays, it has been suggested that fetuin A protects against lethal systemic infection through the inhibition of high mobility group box 1 (HMGB1) protein accumulation and release (Li <i>et al.</i>). Fetuin A acts as a natural antagonist against specific TGF-β and BMP signaling proteins, blocking osteogenic differentiation of rat bone marrow cells (Demetriou <i>et al.</i>). This protein contains a His-residue tag at the carboxyl end of the polypeptide chain. For consistency and reproducibility across your applications, fetuin A from STEMCELL comes lyophilised with ≥94% purity, and endotoxin levels are verified to be ≤1.0 EU/μg protein.
UOM:
1 * 1 EA
New Product
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Numéro de catalogue:
(STMC100-0956)
Fournisseur:
STEMCELL Technologies
Description:
cGMP, serum-free, and xeno-free medium for the expansion of human T cells.
UOM:
1 * 500 mL
New Product
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Numéro de catalogue:
(STMC100-1636)
Fournisseur:
STEMCELL Technologies
Description:
Rat monoclonal antibody against mouse Ly-6C, PE-conjugated.
UOM:
1 * 1 EA
New Product
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Numéro de catalogue:
(STMC100-1620)
Fournisseur:
STEMCELL Technologies
Description:
Rat monoclonal antibody against mouse IL-4, APC-conjugated.
UOM:
1 * 1 EA
New Product
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Numéro de catalogue:
(STMC100-1633)
Fournisseur:
STEMCELL Technologies
Description:
Rat monoclonal antibody against mouse CD8a, unconjugated.
UOM:
1 * 1 EA
New Product
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Numéro de catalogue:
(STMC100-1628)
Fournisseur:
STEMCELL Technologies
Description:
Rat monoclonal antibody against mouse CD127, PE-conjugated.
UOM:
1 * 1 EA
New Product
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Numéro de catalogue:
(STMC100-1245)
Fournisseur:
STEMCELL Technologies
Description:
Serum-free and sex steroid-modular kit for the expansion and differentiation of human fallopian tube organoids.
UOM:
1 * 1 Kit
New Product
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Fournisseur:
STEMCELL Technologies
Description:
Monokine induced by interferon-gamma (MIG), or CXCL9, is a member of the CXC chemokine family. MIG is closely related to two other chemokines: CXCL10 and CXCL11, all of which signal through the CXCR3 receptor (Ding <i>et al.</i>). MIG is secreted by a variety of immune cells including T cells, NK cells, dendritic cells, macrophages, and eosinophils, as well as non-immune cells including hepatic stellate cells, preadipocytes, thyrocytes, endothelial cells, tumor cells, fibroblasts, and glial cells of the central nervous system. MIG has also been shown to act as a chemoattractant for activated T cells and for tumor-infiltrating leukocytes (TILs), but not for neutrophils or for monocytes. MIG has also been reported to be both a tumor suppressor and tumor promoter in various types of cancer.
Numéro de catalogue:
(STMC100-1381)
Fournisseur:
STEMCELL Technologies
Description:
Stimulating T cells with SARS-CoV-2 (Spike Protein) Delta/B.1.617.2 WT reference peptide pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. This peptide pool is a lyophilised mixture of 27 peptides from the spike glycoprotein of the wild-type SARS-CoV-2 virus. Consisting of the wild-type peptides that correspond to the mutated portions of the spike protein found in the SARS-CoV-2 Delta variant (B.1.617.2), this pool is recommended to be used as a reference for the SARS-CoV-2 (Spike Protein) Delta/B.1.617.2 Mutation Peptide Pool. Through interactions with the angiotensin-converting enzyme 2 (ACE2) receptor, the spike protein enables the virus to attach to the cell membrane, and plays a critical role in viral entry (Hoffmann <i>et al.</i>; Walls <i>et al.</i>). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.
UOM:
1 * 1 PE
New Product
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Fournisseur:
STEMCELL Technologies
Description:
Immunomagnetic positive selection of human cells with your own mouse IgG1 antibody.
Fournisseur:
STEMCELL Technologies
Description:
Immunomagnetic enrichment of untouched human hematopoietic progenitor cells.
Numéro de catalogue:
(STMC17864)
Fournisseur:
STEMCELL Technologies
Description:
Immunomagnetic positive selection of human memory B cells.
UOM:
1 * 1 Kit
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Numéro de catalogue:
(STMC17849)
Fournisseur:
STEMCELL Technologies
Description:
Immunomagnetic positive selection of human CD271+ cells.
UOM:
1 * 1 KIT
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Fournisseur:
STEMCELL Technologies
Description:
Rat monoclonal IgG2b antibody against mouse CD24, PerCP-Cy5.5-conjugated.
Fournisseur:
STEMCELL Technologies
Description:
Mouse monoclonal IgG1 antibody against human, cynomolgus nestin, Alexa Fluor® 488-conjugated.
Fournisseur:
STEMCELL Technologies
Description:
Interleukin 6 (IL-6) is a pleiotropic growth factor with the wide range of biological activities in immune regulation, hematopoiesis, and oncogenesis. IL-6 is produced by a variety of cell types including T cells, B cells, monocytes and macrophages, fibroblasts, hepatocytes, vascular endothelial cells, and various tumor cell lines. On its own or in combination with other factors such as IL-2 and interferon-γ, IL-6 stimulates the proliferation of B cells, T cells, and hybridoma cells (Hirano <i>et al.</i>; Mihara <i>et al.</i>; Tanaka et al). In combination with cytokines such as IL-3, GM-CSF and SCF, IL-6 has been shown to promote hematopoietic progenitor cell proliferation and differentiation in vitro. IL-6 signals through a cell surface type I cytokine receptor complex consisting of the ligand-binding IL-6α (CD126) and the signal-transducing gp130 subunits. The binding of IL-6 to its receptor system includes activation of JAK/STAT signaling pathway (Mihara <i>et al.</i>; Peters <i>et al.</i>; Tanaka <i>et al.</i>).
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