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Antilichamen
Itemnummer:
(BOSSBS-4278R-HRP)
Leverancier:
Bioss
Omschrijving:
This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described. [provided by RefSeq].
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-11733R-A488)
Leverancier:
Bioss
Omschrijving:
Myotubularin and the myotubularin-related proteins (MTMR1-9) belong to a highly conserved family of eukaryotic phosphatases. They are protein tyrosine phosphatases that utilize inositol phospholipids, rather than phosphoproteins, as substrates. MTMR family members hydrolyze both Phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2. MTMR2 interacts with MTMR5, an inactive family member that increases the enzymatic activity of MTMR2 and dictates its subcellular localization. Mutations in MTMR2 cause autosomal recessive Charcot-Marie-Tooth type 4B1 (CMT4B1), which is characterized by reduced nerve conduction velocities, focally folded myelin sheaths and demyelination. MTMR3 and MTMR4 can either interact with each other or self associate. MTMR6 regulates the activity of the calcium-activated potassium channel 3.1. MTMR9 regulates the activity of MTMR7 and MTMR8.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-8353R-A555)
Leverancier:
Bioss
Omschrijving:
Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). The first step in the ubiquitination process requires the ATP-dependent activation of the ubiquitin C-terminus and the assembly of multi-ubiquitin chains by the E1 enzyme. The ubiquitin chain is then conjugated to the E2 enzyme to generate an intermediate ubiquitin-E2 complex. The E3 enzyme then catalyzes the transfer of ubiquitin from E2 to the appropriate protein substrate, thereby targeting that substrate for degradation. A wide range of enzymes facilitate this proteolytic ubiquitin pathway, one of which is UBE2E2 (also known as UBCH8 in human), which functions as an E2 enzyme and catalyzes the ATP-dependent covalent attachment of ubiquitin to target proteins, thereby playing an important role in protein degradation.
UOM:
1 * 100 µl
Itemnummer:
(USBIS4283-27-PE)
Leverancier:
US Biological
Omschrijving:
Anti-STK16 Rabbit Polyclonal Antibody (PE (Phycoerythrin))
UOM:
1 * 200 µl
Itemnummer:
(USBIS4283-48A-PE)
Leverancier:
US Biological
Omschrijving:
Anti-STK31 Rabbit Polyclonal Antibody (PE (Phycoerythrin))
UOM:
1 * 200 µl
Itemnummer:
(USBIS5329-03-APC)
Leverancier:
US Biological
Omschrijving:
Anti-Solute Carrier Family 3 Rabbit Polyclonal Antibody (APC (Allophycocyanin))
UOM:
1 * 200 µl
Itemnummer:
(USBIS4283-34-AP)
Leverancier:
US Biological
Omschrijving:
Anti-SRPK3 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
UOM:
1 * 200 µl
Itemnummer:
(BOSSBS-8107R-A555)
Leverancier:
Bioss
Omschrijving:
CCDC129
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-3866R-A555)
Leverancier:
Bioss
Omschrijving:
Protor-1 plays an important role in regulation of PDGF receptor expression and in modulation of PDGF signaling. It is thought that Protor-1 may act as a tumor suppressor in breast cancer.
UOM:
1 * 100 µl
Leverancier:
Biotium
Omschrijving:
Recognizes a protein of 110 kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.This MAb is superb for staining of formalin/paraffin tissues.
Itemnummer:
(USBIA2299-59F)
Leverancier:
US Biological
Omschrijving:
Anti-APOC1 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Itemnummer:
(USBI043857-HRP)
Leverancier:
US Biological
Omschrijving:
Anti-WDR82 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
UOM:
1 * 200 µl
Itemnummer:
(USBIR2031-32B)
Leverancier:
US Biological
Omschrijving:
Anti-RPS6 Rabbit Polyclonal Antibody
UOM:
1 * 10 ST
Itemnummer:
(USBIR2031-52D)
Leverancier:
US Biological
Omschrijving:
Anti-Ricin communis RCA60 Mouse Monoclonal Antibody [clone: 5E781]
UOM:
1 * 500 µG
Itemnummer:
(USBI043858-AP)
Leverancier:
US Biological
Omschrijving:
Anti-DPH7 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
UOM:
1 * 200 µl
Itemnummer:
(USBI043857-PE)
Leverancier:
US Biological
Omschrijving:
Anti-WDR82 Rabbit Polyclonal Antibody (PE (Phycoerythrin))
UOM:
1 * 200 µl
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 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
Dit product is gemarkeerd als beperkt en kan enkel gekocht worden door goedgekeurde verzendingsaccounts. Als u hulp nodig heeft gelieve dan het VWR-Regelgevend Departement te contacteren via regulatory_affairs@vwr.com.
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