Antilichamen
Itemnummer:
(BOSSBS-8140R-A647)
Leverancier:
Bioss
Omschrijving:
CCDC87
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-8140R-CY5)
Leverancier:
Bioss
Omschrijving:
CCDC87
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-15487R-CY7)
Leverancier:
Bioss
Omschrijving:
HIF Prolyl Hydroxylases.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-7922R-HRP)
Leverancier:
Bioss
Omschrijving:
This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit. This protein is a specific target of S6 kinase 1 and regulates cell growth. Two transcript variants that encode different protein isoforms have been identified. [provided by RefSeq, Jul 2008].
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-11362R-A555)
Leverancier:
Bioss
Omschrijving:
Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-3989R-A750)
Leverancier:
Bioss
Omschrijving:
Glycogen synthase catalyses the rate-limiting step in glycogen synthesis. Its activity is regulated by a complex phosphorylation-dephosphorylation mechanism and by allosteric stimulators and inhibitors. Two isozymes of synthase, a skeletal muscle type (Glycogen synthase 1 - GYS1) and a liver type (Glycogen synthase 2 - GYS2), have been identified.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-11362R-CY5)
Leverancier:
Bioss
Omschrijving:
Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-3989R-A680)
Leverancier:
Bioss
Omschrijving:
Glycogen synthase catalyses the rate-limiting step in glycogen synthesis. Its activity is regulated by a complex phosphorylation-dephosphorylation mechanism and by allosteric stimulators and inhibitors. Two isozymes of synthase, a skeletal muscle type (Glycogen synthase 1 - GYS1) and a liver type (Glycogen synthase 2 - GYS2), have been identified.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-7814R-CY7)
Leverancier:
Bioss
Omschrijving:
The protein encoded by this gene is a serine/threoninekinase involved in cell cycle regulation. The encoded protein isfound in a centrosomal complex with FEZ1, a neuronal protein thatplays a role in axonal development. Defects in this gene are acause of polycystic kidney disease (PKD). Several transcriptvariants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2010].
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-7922R-A750)
Leverancier:
Bioss
Omschrijving:
This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit. This protein is a specific target of S6 kinase 1 and regulates cell growth. Two transcript variants that encode different protein isoforms have been identified.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-11596R-A647)
Leverancier:
Bioss
Omschrijving:
Transcription factors, OTX1 and OTX2, are two murine homologs of the Drosophila orthodenticle (OTD), show a limited amino acid sequence divergence. OTX1 and OTX2 play an important role during early and later events required for proper brain development in that they are involved in the processes of induction, specification and regionalization of the brain. OTX1 is involved in corticogenesis, sensory organ development and pituitary functions, while OTX2 is necessary earlier in development, for the correct anterior neural plate specification and organization of the primitive streak. OTX2 is also required in the early specification of the neuroectoderm, which is destined to become the fore-midbrain, and both OTX1 and OTX2 co-operate in patterning the developing brain through a dosage-dependent mechanism. A molecular mechanism depending on a precise threshold of OTX proteins is necessary for the correct positioning of the isthmic region and for anterior brain patterning. The genes which encode OTX1 and OTX2 map to human chromosomes 2p15 and 14q21-q22, respectively.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-11596R-FITC)
Leverancier:
Bioss
Omschrijving:
Transcription factors, OTX1 and OTX2, are two murine homologs of the Drosophila orthodenticle (OTD), show a limited amino acid sequence divergence. OTX1 and OTX2 play an important role during early and later events required for proper brain development in that they are involved in the processes of induction, specification and regionalization of the brain. OTX1 is involved in corticogenesis, sensory organ development and pituitary functions, while OTX2 is necessary earlier in development, for the correct anterior neural plate specification and organization of the primitive streak. OTX2 is also required in the early specification of the neuroectoderm, which is destined to become the fore-midbrain, and both OTX1 and OTX2 co-operate in patterning the developing brain through a dosage-dependent mechanism. A molecular mechanism depending on a precise threshold of OTX proteins is necessary for the correct positioning of the isthmic region and for anterior brain patterning. The genes which encode OTX1 and OTX2 map to human chromosomes 2p15 and 14q21-q22, respectively.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-11596R-CY3)
Leverancier:
Bioss
Omschrijving:
Transcription factors, OTX1 and OTX2, are two murine homologs of the Drosophila orthodenticle (OTD), show a limited amino acid sequence divergence. OTX1 and OTX2 play an important role during early and later events required for proper brain development in that they are involved in the processes of induction, specification and regionalization of the brain. OTX1 is involved in corticogenesis, sensory organ development and pituitary functions, while OTX2 is necessary earlier in development, for the correct anterior neural plate specification and organization of the primitive streak. OTX2 is also required in the early specification of the neuroectoderm, which is destined to become the fore-midbrain, and both OTX1 and OTX2 co-operate in patterning the developing brain through a dosage-dependent mechanism. A molecular mechanism depending on a precise threshold of OTX proteins is necessary for the correct positioning of the isthmic region and for anterior brain patterning. The genes which encode OTX1 and OTX2 map to human chromosomes 2p15 and 14q21-q22, respectively.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-8228R-CY5.5)
Leverancier:
Bioss
Omschrijving:
The FAH family contains two highly homologous 314 amino acid proteins, designated FAHD2A (fumarylacetoacetate hydrolase domain-containing protein 2A) and FAHD2B (fumarylacetoacetate hydrolase domain-containing protein 2A). FAHD2A and B utilize calcium and magnesium as cofactors, and may possess hydrolase activity. The genes encoding FAHD2A/B map to human chromosome 2, the second largest human chromosome, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstré°‰ syndrome, is also associated with mutations to chromosome 2.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-4117R-CY3)
Leverancier:
Bioss
Omschrijving:
Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Appears be required for postnatal control of vascular regression in the eye. Required for posterior patterning of the epiblast during gastrulation.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-11597R-CY3)
Leverancier:
Bioss
Omschrijving:
Transcription factors, OTX1 and OTX2, are two murine homologs of the Drosophila orthodenticle (OTD), show a limited amino acid sequence divergence. OTX1 and OTX2 play an important role during early and later events required for proper brain development in that they are involved in the processes of induction, specification and regionalization of the brain. OTX1 is involved in corticogenesis, sensory organ development and pituitary functions, while OTX2 is necessary earlier in development, for the correct anterior neural plate specification and organization of the primitive streak. OTX2 is also required in the early specification of the neuroectoderm, which is destined to become the fore-midbrain, and both OTX1 and OTX2 co-operate in patterning the developing brain through a dosage-dependent mechanism. A molecular mechanism depending on a precise threshold of OTX proteins is necessary for the correct positioning of the isthmic region and for anterior brain patterning. The genes which encode OTX1 and OTX2 map to human chromosomes 2p13 and 14q21-q22, respectively.
UOM:
1 * 100 µl
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De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
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