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Antilichamen
Itemnummer:
(BOSSBS-15544R-A750)
Leverancier:
Bioss
Omschrijving:
IER2.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-15544R-A680)
Leverancier:
Bioss
Omschrijving:
IER2.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-8154R-A350)
Leverancier:
Bioss
Omschrijving:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008].
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-3899R-CY5.5)
Leverancier:
Bioss
Omschrijving:
Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D(3)) and calcitriol (1-alpha,25-dihydroxyvitamin D(3)). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23-hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-13503R-CY5)
Leverancier:
Bioss
Omschrijving:
Vascular wall-linked protein, or Vasculin, is primarily expressed in the arterial wall and in plasma. It is also differentially expressed in human atherogenesis. Alternative splicing of exon 3 of the Vasculin gene produces three variants. Vasculin binds to and activates the minimal self-sufficient promoter element (MSPE) of the mouse Ada gene promoter and binds to and partially suppresses the GC-rich promoter of the nonhomologous human TOP2A gene promoter. It acts as a nuclear factor that can form complexes with TATA-binding proteins, transcription factors TFIIB and TFIIF, RNA polymerase II and p300. The regulated expression of Vasculin in plaques suggests that it may be involved in atherogenesis, and its presence in plasma may implicate Vasculin as a marker for atherosclerosis.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-6119R-A750)
Leverancier:
Bioss
Omschrijving:
May be involved in the regulation of cellular proliferation and/or differentiation.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-6120R-CY3)
Leverancier:
Bioss
Omschrijving:
ZNF431 belongs to the krueppel C2H2-type zinc-finger protein family and is probably involved in transcriptional regulation.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-0814R-A488)
Leverancier:
Bioss
Omschrijving:
Primary component of whey, it binds retinol and is probably involved in the transport of that molecule.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-2362R-A555)
Leverancier:
Bioss
Omschrijving:
Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-13460R-A680)
Leverancier:
Bioss
Omschrijving:
GMPPA is a GDP-mannose pyrophosphorylase which catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose, in the production of N-linked oligosaccharides.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-7093R-HRP)
Leverancier:
Bioss
Omschrijving:
ZNHIT1, Zinc finger HIT domain containing protein 1, appears to play a role in p53-mediated apoptosis induction.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-11188R-FITC)
Leverancier:
Bioss
Omschrijving:
Transcription factor that binds to the enhancer element PRE-I (positive regulatory element-I) of the IL-4 gene. Might change the DNA-binding specificity of other transcription factors and recruit them to unusual DNA sites.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-7094R-A750)
Leverancier:
Bioss
Omschrijving:
This gene is specifically expressed in the thymus, and encodes a protein that is localised to the mitochondrion. The expression of this gene is inducible by p53, and it is thought to play an important role in mediating p53-dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-3418R-A555)
Leverancier:
Bioss
Omschrijving:
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-11972R-CY5)
Leverancier:
Bioss
Omschrijving:
Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner. Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) and GPER1 to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-6229R-CY3)
Leverancier:
Bioss
Omschrijving:
ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID-3 inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. May inhibit other transcription factors.
UOM:
1 * 100 µl
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 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
Dit product is gemarkeerd als beperkt en kan enkel gekocht worden door goedgekeurde verzendingsaccounts. Als u hulp nodig heeft gelieve dan het VWR-Regelgevend Departement te contacteren via regulatory_affairs@vwr.com.
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