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Antilichamen
Itemnummer:
(BOSSBS-9212R)
Leverancier:
Bioss
Omschrijving:
The serine proteinase inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, including the control of blood coagulation, complement activation, programmed cell death and development. Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. SerpinB11 (serpin peptidase inhibitor, clade B (ovalbumin), member 11), also known as EPIPIN or SERPIN11, is a 392 amino acid cytoplasmic protein that belongs to the Ov-serpin subfamily and serpin family. Like other members of the serpin family, SerpinB11 has been identified as a noninhibitory intracellular protein. The gene encoding SerpinB11 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-9209R)
Leverancier:
Bioss
Omschrijving:
ZPI, also known as SERPINA10 (serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10) or PZI, is a 444 amino acid secreted protein that functions as a Protein Z-dependent protease inhibitor. Expressed by the liver, ZPI is secreted into the plasma where, in the presence of calcium, Protein Z and phospholipids, it inhibits the activated pro-coagulation factors X and XI (Factor X and Factor XI). This inhibition helps properly regulate intravenous blood clotting. ZPI, a member of the serpin protein family, contains five potential N-linked glycosylation sites and a tyrosine at position 387 which, when disrupted, renders ZPI inactive. Defects in the gene encoding ZPI may increase susceptibility to venous thrombosis, the formation of blood clots within a vein.
UOM:
1 * 100 µl
Leverancier:
Biotium
Omschrijving:
This antibody reacts with the TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with this MAb is completely blocked by the peptide used for raising this antibody. TGF alpha (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
Itemnummer:
(ABGEAP20542C)
Leverancier:
Abgent
Omschrijving:
Anti-NDUFA9 Rabbit Polyclonal Antibody
UOM:
1 * 400 µl
Itemnummer:
(ABGEAP3781K)
Leverancier:
Abgent
Omschrijving:
Anti-ERBB2 Rabbit Polyclonal Antibody
UOM:
1 * 400 µl
Itemnummer:
(ABGEAP3781M)
Leverancier:
Abgent
Omschrijving:
Anti-ERBB2 Rabbit Polyclonal Antibody
UOM:
1 * 400 µl
Itemnummer:
(ABGEAP3120A)
Leverancier:
Abgent
Omschrijving:
Anti-ERBB2 Rabbit Polyclonal Antibody
UOM:
1 * 400 µl
Itemnummer:
(ABGEAP3094A)
Leverancier:
Abgent
Omschrijving:
Anti-ERBB2 Rabbit Polyclonal Antibody
UOM:
1 * 400 µl
Itemnummer:
(ABGEAP3781B)
Leverancier:
Abgent
Omschrijving:
Anti-ERBB2 Rabbit Polyclonal Antibody
UOM:
1 * 400 µl
Itemnummer:
(USBIB2553-10A-FITC)
Leverancier:
US Biological
Omschrijving:
Anti-BMP3 Rabbit Polyclonal Antibody (FITC (Fluorescein))
UOM:
1 * 200 µl
Itemnummer:
(USBIB2553-09-APC)
Leverancier:
US Biological
Omschrijving:
Anti-BMP2K Rabbit Polyclonal Antibody (APC (Allophycocyanin))
UOM:
1 * 200 µl
Itemnummer:
(USBIB2553-09-HRP)
Leverancier:
US Biological
Omschrijving:
Anti-BMP2K Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
UOM:
1 * 200 µl
Itemnummer:
(USBIC2085-54D)
Leverancier:
US Biological
Omschrijving:
Anti-CSNK1D Sheep Polyclonal Antibody
UOM:
1 * 1 EA
Itemnummer:
(USBIC2099-93L)
Leverancier:
US Biological
Omschrijving:
Anti-CCR4 Rabbit Polyclonal Antibody
UOM:
1 * 50 µl
Itemnummer:
(USBIA2275-85L-PE)
Leverancier:
US Biological
Omschrijving:
Anti-APP Rabbit Polyclonal Antibody (PE (Phycoerythrin))
UOM:
1 * 200 µl
Leverancier:
Biotium
Omschrijving:
This antibody recognizes an antigen associated with the nuclear membrane expressed in human cells. It can be used to stain the nuclear membrane in cell or tissue preparations and can be used as a marker of the nuclear membrane in subcellular fractions. It produces a ring pattern around the nucleus of cells of normal and malignant cells and may be used to stain the nuclear membrane of cells in fixed or frozen tissue sections. ,The nuclear envelope (also known as the perinuclear envelope, nuclear membrane, nucleolemma or karyotheca) is the double membrane of the nucleus that encloses genetic material in eukaryotic cells. It separates the contents of the nucleus (DNA in particular) from the cytosol (cytoplasm). Numerous nuclear pores are present on the nuclear envelope to facilitate and regulate the exchange of materials (for example, proteins and RNA) between the nucleus and the cytoplasm. The space between the two membranes that make up the nuclear envelope is called the perinuclear space (also called the perinuclear cisterna), and is usually about 20 - 40 nm wide. Each of the two membranes is composed of a lipid bilayer. The outer membrane is continuous with the rough endoplasmic reticulum. The inner membrane is erected upon the nuclear lamina, a network of intermediate filaments made of lamin, that plays a role in mitosis and meiosis. The type of lamins present are A, B1, B2, and C. The nuclear envelope may also play a role in the disposition of chromatin inside the nucleus. The lamina acts as a site of attachment for chromosomes. It also acts like a shield for the nucleus. During prophase in mitosis, the chromatids begin condensing to form chromosomes, and the nuclear envelope begins to disintegrate. During metaphase, the nuclear envelope is completely disintegrated, and the chromosomes can be pulled apart as chromatids by the spindle fibers.
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 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
Dit product is gemarkeerd als beperkt en kan enkel gekocht worden door goedgekeurde verzendingsaccounts. Als u hulp nodig heeft gelieve dan het VWR-Regelgevend Departement te contacteren via regulatory_affairs@vwr.com.
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