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Antilichamen
Itemnummer:
(BOSSBS-7772R)
Leverancier:
Bioss
Omschrijving:
Anti-SEPT14 Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-8510R)
Leverancier:
Bioss
Omschrijving:
Anti-XRCC4 Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-8067R)
Leverancier:
Bioss
Omschrijving:
Anti-SRRM2 Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-7982R)
Leverancier:
Bioss
Omschrijving:
Anti-HOXC9 Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Itemnummer:
(EVBIEB12525)
Leverancier:
Everest Biotech
Omschrijving:
Anti-CXCR1 Goat Polyclonal Antibody
UOM:
1 * 0,1 mg
Itemnummer:
(BOSSBS-2389R-CY7)
Leverancier:
Bioss
Omschrijving:
Component of the epithelial apical junction complex that may function as an homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with AMICA1/JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, AMICA1 induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-5807R-CY3)
Leverancier:
Bioss
Omschrijving:
ELMO1 is involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. ELMO1 acts in association with DOCK1 and CRK and was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. It is belived to enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-0605R-CY5)
Leverancier:
Bioss
Omschrijving:
Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-13565R-A488)
Leverancier:
Bioss
Omschrijving:
ZBTB12
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-2646R-A555)
Leverancier:
Bioss
Omschrijving:
Lymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG-3 to CD4.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-2706R-CY3)
Leverancier:
Bioss
Omschrijving:
SIGLEC10 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It preferentially binds to alpha2,3- or 2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. SIGLEC10 interacts with PTPN6/SHP-1 upon phosphorylation. The protein is expressed by peripheral blood leukocytes (eosinophils, monocytes and a natural killer cell subpopulation).
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-2636R-CY3)
Leverancier:
Bioss
Omschrijving:
Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-2565R-HRP)
Leverancier:
Bioss
Omschrijving:
Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-6431R-A647)
Leverancier:
Bioss
Omschrijving:
Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-6431R-A488)
Leverancier:
Bioss
Omschrijving:
Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-15043R-A680)
Leverancier:
Bioss
Omschrijving:
Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf182 gene product has been provisionally designated C1orf182 pending further characterization.
UOM:
1 * 100 µl
Bel voor prijs
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
Dit product is gemarkeerd als beperkt en kan enkel gekocht worden door goedgekeurde verzendingsaccounts. Als u hulp nodig heeft gelieve dan het VWR-Regelgevend Departement te contacteren via regulatory_affairs@vwr.com.
Bijkomende documentatie kan noodzakelijk zijn voor dit item. Een VWR-verantwoordelijke zal contact opnemen met u indien nodig.
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