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Antilichamen
Itemnummer:
(BOSSBS-15279R-A555)
Leverancier:
Bioss
Omschrijving:
Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterised by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia. The C7orf64 gene product has been provisionally designated C7orf64 pending further characterisation.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-6884R-A350)
Leverancier:
Bioss
Omschrijving:
Plays a role in regulating placenta growth. May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids (By similarity).
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-15278R-CY3)
Leverancier:
Bioss
Omschrijving:
C7orf63.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-1011R-A750)
Leverancier:
Bioss
Omschrijving:
Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodelling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 X4 isolates and as a primary receptor for some HIV-2 isolates. Promotes Env-mediated fusion of the virus. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-10182R-CY7)
Leverancier:
Bioss
Omschrijving:
FUT5
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-6558R-HRP)
Leverancier:
Bioss
Omschrijving:
May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-13584R-A350)
Leverancier:
Bioss
Omschrijving:
ZBTB8A
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-6560R-CY3)
Leverancier:
Bioss
Omschrijving:
The Oxysterol-binding protein (OSBP) family of proteins consist of OSBP (OSBP1) and OSBP2 (ORP-4), which share a high overall similarity. OSBPs are involved in lipid metabolism and signal transduction, as well as vesicle transport, and can translocate to the periphery of Golgi membranes when they are bound to oxysterols. The OSBP protein transports sterols from lysosomes to the nucleus, where sterols downregulate the genes for HMG synthetase, HMG-CoA reductase and the low density lipoprotein receptor (LDLR). OSBP localizes to the cytosol and is widely expressed, while OSBP2 is mainly detected in testis, retina and fetal liver. The extracellular signal-regulated kinase (ERK) signaling pathway is controlled by OSBP via its cholesterol-binding properties. OSBP binds with a high affinity to 25-hydroxy-cholesterol (25-HC), a suppressor of cholesterol synthesis gene transcription in cultured cells.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-10122R-A555)
Leverancier:
Bioss
Omschrijving:
CD130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-10122R-A350)
Leverancier:
Bioss
Omschrijving:
CD130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-2740R-A680)
Leverancier:
Bioss
Omschrijving:
p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalises to the presumptive sites of damage, p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalises to the presumptive sites of damage, specifically, double strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-11650R-FITC)
Leverancier:
Bioss
Omschrijving:
ALS2CR3 may regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-1559R-A555)
Leverancier:
Bioss
Omschrijving:
This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-11650R-CY3)
Leverancier:
Bioss
Omschrijving:
ALS2CR3 may regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-11650R-A647)
Leverancier:
Bioss
Omschrijving:
ALS2CR3 may regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-8175R-CY3)
Leverancier:
Bioss
Omschrijving:
Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.
UOM:
1 * 100 µl
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 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
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